Antidepressants (SSRIs, SNRIs, MAOs, TCAs, TeCAs)

Discussion in 'Treatments' started by Pat, May 10, 2012.

    1. attheedgeofscience
      No Mood

      attheedgeofscience Member Podcast Patron Mighty Benefactor Hall of Fame

      Location:
      Denmark
      Tinnitus Since:
      Resolved since 2016
      Cause of Tinnitus:
      Unknown (medication, head injury)
      If I were you, I would insist on a proper (visual) inspection of your ears and eustachian tube when seeing your new ENT. You never know what you might find in there - even if the ENTs thinks everything is fine (I speak from experience). Do you feel equal pressure in your ears when doing the valsalva maneuver?

      About your anxiety, I assume it is relatively mild given you are well functioning otherwise (and working in the health care industry). For mild anxiety, I can recommend hypnosis - with a good hypnotist, it will take it away more or less instantly (medication is crap). Again, I speak from experience.

      Don't expect much from the psychiatrist. In fact, I (personally) wouldn't even bother. If you need meds, get them from your ENT next week.

      Best of luck.
       
    2. Bhavin

      Bhavin Member

      Tinnitus Since:
      6 weeks
      HI,.. i had taken GROFENAC retard diclofenac sodium 100 mg ...and cortancyl 5 mg and Laroxyl Comprime..and after two days ..My T started.....i m thinking that because of above medications i got T...
       
    3. Lulubug69
      Artistic

      Lulubug69 Member

      Tinnitus Since:
      9/2013
      I was such a mess when the ringing started. I actually went off my Welbutrin, anti depressant.
      I am sensitive to these types of drugs to begin with, that I was not willing to try another or continue on the only one I could take. I had decided for myself that the anxiety about it was to my detriment. I couldn't stop focusing on it. That's why I went with an herb. I chose (with the help of my Nurse Practitioner) passionflower. It works like the drug valium. It helped me to calm during the day and get a restful sleep at night. I think the anxiety about this condition starts to consume us if we don't address it. I'd advise a conversation with doctor first about anxiety, then maybe an anti depressant next. I think taking meds right away can make it worse in some people. Adapting to these drugs can be awful.That's why I think anyone that gets diagnosed with T, sees a Tinnitus specialist first.
       
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    4. demi
      No Mood

      demi Member Benefactor

      Tinnitus Since:
      12/2012
      I was prescribed Paxil/Paroxetine for my anxiety, but fear it may make tinnitus worse?
       
    5. gary
      Transparent

      gary Member Benefactor

      Location:
      Macomb, MI. USA
      Tinnitus Since:
      07/2012
      Cause of Tinnitus:
      Who Knows
      Hi Demi, I just googled Paxil and tinnitus, several sites came up. you might want to google it...
       
    6. demi
      No Mood

      demi Member Benefactor

      Tinnitus Since:
      12/2012
      I am just confused because I have read that -

      "While antidepressant medications like Zoloft, Paxil, and Xanax may cause tinnitus symptoms, they are sometimes effective at treating tinnitus symptoms, as well."
       
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    7. gary
      Transparent

      gary Member Benefactor

      Location:
      Macomb, MI. USA
      Tinnitus Since:
      07/2012
      Cause of Tinnitus:
      Who Knows
      Demi, I understand. I take Valium and it helps me chill out, it does not bring on T for me or make it worse. My wife takes Paxil & has no tinnitus, but Paxil does help her with anxiety. Truth is, you won't know until is you try it. I am sure your Dr. has told you Paxil may take three weeks or so before you feel a change in anxiety, but I would imagine it would not take long at all, for it to affect your T.

      With T it is a hit or miss thing with foods & meds. Some say caffeine bothers or triggers their T, I can have all the caffeine I want and it does not affect my T level at all...
       
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    8. amm12

      amm12 Member

      Location:
      Fort Worth, Texas
      Tinnitus Since:
      01/2014
      Ahh sorry for another post, I'll delete it if I have to. But I just got prescribed Lexapro for my anxiety, and Trazodone for my insomnia. I'm trying to be very careful about what to take as not to make the tinnitus worse. Are these drugs safe? Or known to have negative effects on tinnitus? Is there a list somewhere of ones to avoid? Thanks!
       
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    9. Lynnette
      Blah

      Lynnette Member Benefactor

      Tinnitus Since:
      Aug 2013
      Hey Amm, I started lexapro 3 month ago for anxiety and depression (and I used klonopin to help me get through the first month of sleeplessness). I really think these medications (antid's) are a toss up if they make T worse or better with people. For me, it hasn't made my T unbearable but it has increased it a bit. It was already pretty loud to begin with. From what I've heard it may decrease in volume over time once my brain settles from the anxiety and depression, but who knows. I've heard of a few people that antid's have really helped them to cope and tune out the T easier as well. I've also heard that upon discontinuing the med the volume may reduce again...I guess I'll see about this in a year or so. I definitely think something to help you sleep is a must right now...lack of sleep is tough on the T and mental state. Everyone is different...my anxiety and depression being reduced to a level that I can cope and live my life is more important to me than my T right now but hopefully I can live without medication in the future!
       
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    10. Magpie
      Sporty

      Magpie Member

      Tinnitus Since:
      04/15/1999
      Here's a list but the Physicians Desk Reference(PDR) is much more accurate:
      http://www.tinnitus-audiology.com/drugs.html
      http://www.pdr.net/

      Remember though it's horses for course and people may respond differently to specific medications. It's important if you feel something is wrong that you contact your doctor
       
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    11. amm12

      amm12 Member

      Location:
      Fort Worth, Texas
      Tinnitus Since:
      01/2014
      Ahh thank you guys, I'll try to read up more about it. Tinnitus is just so unbelievable, especially because all of the information about it is incredibly inconsistent. I'm just baffled, it's like a unbreakable curse.
       
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    12. carol kane
      Wishful

      carol kane Member

      Location:
      Lincolnshire united kingdom
      Tinnitus Since:
      11/13
      I personally would avoid the whole damn lot, NO drugs for me and my T ... au naturel for me is the only way, as most drugs are ototoxic ( so i'm told ) i just can't risk it!!! God help me if and when i need an Antibiotic, because i just won't take it!!! and as for pain killers ... well i suppose it depends on the level of the pain, again, i'll pass on those too!!
       
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    13. amm12

      amm12 Member

      Location:
      Fort Worth, Texas
      Tinnitus Since:
      01/2014
      Man, yeah I wish I could do that. I have major panic and anxiety disorders though, so I gotta find something. As for pain killers, yeah, ever since the tinnitus, I'm just gonna skip out on those and endure it because the ringing demolishes me more than the physical pain :(
       
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    14. LadyDi
      Busy

      LadyDi Member Benefactor

      Location:
      Florida, USA
      Tinnitus Since:
      06/2013
      Cause of Tinnitus:
      Barotrauma/airplane
      Hey Carol; while I respect your right to choose and advocate natural remedies, is not true that "most drugs are ototoxic." The lists you see circulating online usually any medication where anyone, ever, has reported ringing of the ears while taking it. First, there is no way to verify the ringing is connected to the drug, And second, these reports can come from a fraction (as in far, far less than one percent) of those taking the prescription.

      Yes, some meds cause or exacerbate tinnitus. But most do not. And anyone with major panic or anxiety disorders should not be afraid to look at appropriate short term meds (administered by a psychiatrist, not a general practitioner) for help.
       
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    15. thenightman

      thenightman Member

      Tinnitus Since:
      04/2009
      hey guys, so whats the general consensus with Amitriptyline? My ENT prescribed it yesterday and said it would likely reduce the volume of my T. But after skimming this thread it seems like it can also make T worse. What would you guys recommend?
       
    16. Golly
      Bookworm

      Golly Member Benefactor

      Location:
      New York City
      Tinnitus Since:
      01/2011
      @thenightman;

      I have generally heard positive things about Amitriptyline. Indeed, I took it myself in low doses (10mg) as a sleep aid years ago. I have discussed it with my doctor as a route to dealing with tinnitus, and he said that he would prescribe. However, his advice, which I have heeded, is that I am better off with Mirtazapine. These are similar drugs in many respects, except that Mirtazapine has fewer negative side effects. One similarity is that they both promote sleep: always a plus when you have tinnitus!

      No one knows for sure, but my guess is that any aggravation to your tinnitus that might be caused by Amitriptyline will vanish upon cessation of the drug.

      -Golly
       
    17. thenightman

      thenightman Member

      Tinnitus Since:
      04/2009
      thanks for the response. I started it last night, I'll let you guys know how it goes.
       
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    18. kenji

      kenji Member

      Tinnitus Since:
      2013
      well i don't feel so bad after all ., i currently take abilify , lithium , nuronton , keeps me treading on ...meds work good . at least my T went down to a little t and then a littler +
       
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    19. I just read this entire thread, some really good info here. I am searching for an AD, as my depression, H and T is getting worse. Anyways thought I would post here that today at the docs I got a prescription for flexril, or cyclobenzaprine, a muscle relaxant. I am currently tapering off clonazepam and hoping this drug will be better for my tmj muscle spasms and ear spasms from H..anywho,, did a google search to check for T and this drug and stumbled upon several studies of where peoples T was significantly reduced while using this med...thought I would share and will let you know..and also read the other day, how T may be caused by muscle impinging facial nerves. Or something like that...maybe thats why, however I think alot of people know T can also stem from the scm muscle in the neck too, trigger points...anyways I hope it works..clonaz works only o.k and wears off quickly..not great for longterm imo...
       
    20. Also, I am not 100% that clonazepam didn't help contribute to my eye and ear issues, after having tmj for ten years, I find it odd that after being on clonazepam for 3 mths, all these symptoms appeared..H, T worsened and crazy eye spasms, and floaters..though I will never really know...but I will be happy to be off it..and I have read other accounts of people getting H and t from this drug..so anyone thinking of taking it should know..just my personal experience and what I have read, I am tapering in hopes my symptoms will get better somewhat..one can only hope :)
       
    21. Jeff M.
      Breezy

      Jeff M. Member Benefactor

      Location:
      La Jolla, CA
      Tinnitus Since:
      Oct. 2012
      Cause of Tinnitus:
      Idiopathic
      my experience with amitriptyline was a nightmare. Weird nighttime awake/sleep episodes. did not help my T. Just my experience nightman....
       
    22. Dr. Ancill

      Dr. Ancill Member Clinician

      Tinnitus Since:
      09/2013
      None of these medications treats tinnitus. They are used to treat the secondary consequences such as anxiety, depression and insomnia which themselves will 'amplify' the tinnitus. These antidepressants will often reduce anxiety, improve depression and increase sleep - so they seem to help the tinnitus but they only treat the secondary elements. Sometimes, especially with the serotonin medications, anxiety will increase - thus increasing the perceived level of tiinitus and that medication will be accused of causing or worsening the tinnitus, This is not what is happening - again, the tinnitus is percieved as worse because of a secondary effect. Amitriptyline in low doses is sedating so it will improve sleep but some patients do not tolerate it (see responses above). Flexoril will likely do very little as TMJ spasms are not major cause of tinnitus although increasing muscles tension will make the tinnitus louder, probably by altering blood through to the inner ear. Different individuals will do better on individual treatments but what works for one will not work for all.
       
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    23. Dr. Ancill

      Dr. Ancill Member Clinician

      Tinnitus Since:
      09/2013
      Also, it does not work. There is a medical axiom that says -a drug with no side effects is a drug with no front effects either.
       
    24. George Brady
      Crappy

      George Brady Member

      Tinnitus Since:
      1985
      Cause of Tinnitus:
      bad meds
      O
      I. Been on it for a year or so. Works for me takes a month or so to kick in so give time.
       
    25. marco bugeja

      marco bugeja Member

      Location:
      Zurrieq
      Tinnitus Since:
      01/2014
      Before I had T I got vertigo for about a month and I had mwrtazapin for anxiety . 2-3 weeks later balance was coming OK but T kicks in . can the anti anxiety pills be the cause for T ?
       
    26. Golly
      Bookworm

      Golly Member Benefactor

      Location:
      New York City
      Tinnitus Since:
      01/2011
      @marco bugeja:

      I assume you are referring to the antidepressant, Mirtazapine (often called Remeron). If so, know that as far as antidepressants go, this drug appears to have a low side-effect profile and is generally not thought to aggravate tinnitus. Of course it is impossible to be sure, but I expect that the onset of your tinnitus is independent of the Mirtazapine.

      -Golly
       
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    27. areilly91

      areilly91 Member

      Location:
      New york
      Tinnitus Since:
      08/2113
      Hello everyone, I had my first intake appt with a psychiatrist two weeks ago. On Wednesday I will be going in to discuss the best course of treatment for my depression/ anxiety. I have always had problems but since my T kicked in full force in August I am really suffering. I do take klonopin to help keep my panic at bay. I tried doxepin and elavil for depression but it immediately affected my ears. My sleep is terrible, always has been. What do you guys suggest I inquire about as far as a med that will alleviate my anxiety/depression without aggravating my ears? I trust your opinions, thank you!
       
    28. kevin b
      Fine

      kevin b Member

      Location:
      Hope well junction, NY
      Tinnitus Since:
      1/2014
      Has anyone had experience starting up on an SSRI and having it increase your ringing but have it go back to normal after a few days or week?
       

    29. http://www.karger.com/Article/FullText/335657

      Tinnitus, the phantom perception of sounds, is a highly prevalent disorder. Although a wide variety of drugs have been investigated off label for the treatment of tinnitus, there is no approved pharmacotherapy. We report an open-label exploratory pilot study to assess the effect of muscle relaxants acting on the central nervous system on tinnitus patients. Cyclobenzaprine at high (30 mg) and low doses (10 mg), orphenadrine (100 mg), tizanidine (24 mg) and eperisone (50 mg) were administered to a maximum of 20 patients per group over a 12-week period. High-dose cyclobenzaprine resulted in a significant reduction in the Tinnitus Handicap Inventory (THI) score between baseline and week 12 in the intention-to-treat sample. On the other hand, other treatments were not effective. These results were confirmed in an explorative analysis where baseline corrected THI and Clinical Global Impression scores at week 12 were compared between groups. The present open trial presents a new promising pharmacotherapy for tinnitus that should be validated in placebo-controlled double-blind trials.

      A thread I found as well....https://www.tinnitustalk.com/threads/cyclobenzaprine-flexeril.525/
       
    30. Grace
      No Mood

      Grace Member

      Tinnitus Since:
      11/14/2013
      I was prescribed 10 mg lexapro two years ago way before my t started ( on top of klonopin when needed) and its been a life saver! Ive always had severe panic and anxiety pre T and it helped me and is still helping me with the T. Lexapro made me more calm and happy but it did take about 3 or 4 monthes before i felt the full effect so i tell even my friends who get on it for anixety and depression to give it some months to actually notice a change :) and it has way less side effects beside any other anti depressant out there is what my doc said and i had none so i reccomend it!
       
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