FGG's Recent Activity

  1. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They are still recruiting. The extra time isn't just for data compiling.

    Aug 15, 2020 at 1:40 PM
  2. FGG liked GlennS's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    This is what I've been saying in response to those here who can really get angry ranting about a lack of R&D money. Money does not directly...

    Aug 15, 2020 at 1:39 PM
  3. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Thankfully, biological problems are in general a lot more solvable than nuclear fusion but people clamor for funding for step 4 without realizing...

    Aug 15, 2020 at 1:39 PM
  4. FGG liked Selah1281's post in the thread Aldosterone and Hearing.

    https://www.usf.edu/news/2019/hearing-loss-may-be-preventable-with-development-new-drug.aspx “The first ever medication to treat age-related...

    Aug 15, 2020 at 1:33 PM
  5. FGG rated serendipity1996's post Agree in the thread 2020 US Presidential Election.

    Jastreboff would probably label us 'flag-wavers' smh.

    Aug 15, 2020 at 3:06 AM
  6. FGG liked Zugzug's post in the thread 2020 US Presidential Election.

    [ATTACH]

    4binuo (1).jpg Aug 15, 2020 at 3:05 AM
  7. FGG rated Zugzug's post Agree in the thread 2020 US Presidential Election.

    To be fair, the "He's not Trump" would be high no matter who the candidate was. Voting out an authoritarian is a pretty motivating thing.

    Aug 15, 2020 at 2:21 AM
  8. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Something to consider along with this is that even if Frequency had been funded by Jeff Bezos, they couldn't have developed FX-322 until Jeff Karp...

    Aug 15, 2020 at 2:19 AM
  9. FGG rated Thuan's post Agree in the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    I believe they are treating hearing loss, or rather as FGG puts it as hearing interference, resulting from Meniere's except this hearing loss...

    Aug 15, 2020 at 2:06 AM
  10. FGG replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    This treatment was originally tested for Meniere's which has an inflammatory component to it. Meniere's is associated with fluctuating hearing...

    Aug 15, 2020 at 2:05 AM
  11. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Will be released 2nd quarter of 2021 (delayed due to COVID-19).

    Aug 14, 2020 at 11:56 PM
  12. FGG rated aot's post Funny in the thread 2020 US Presidential Election.

    "I was on the computer the other day. Beautiful computer, the computer. Beautiul. And I came upon the website called Tinnitus Talk. And Tinnitus...

    Aug 14, 2020 at 11:17 PM
  13. FGG liked aot's post in the thread 2020 US Presidential Election.

    I mean, he didn't exactly "lay off" his other brother during his struggles with the alcoholism and depression that led him to suicide. What makes...

    Aug 14, 2020 at 11:17 PM
  14. FGG rated Zugzug's post Good Question in the thread 2020 US Presidential Election.

    To put it mildly. In a completely unrelated note, do you think Jastreboff (and other TRT professionals) read these threads?

    Aug 14, 2020 at 11:05 PM
  15. FGG replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    It helps with inflammation, which is a factor in Meniere's and acute noise induced hearing loss.

    Aug 14, 2020 at 8:29 PM
  16. FGG rated tommyd87's post Agree in the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    Musk does best when he has science supporting his claims and also when he has an option which can disrupt the mainstream market. I predict that...

    Aug 14, 2020 at 7:47 PM
  17. FGG replied to the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    I would put much more stock in this if he had a chief scientific officer specializing in artificial neural interfacing that could at least speak...

    Aug 14, 2020 at 7:47 PM
  18. FGG replied to the thread 2020 US Presidential Election.

    If he was grieving the illness of his brother and i saw him in person, I would refrain from voicing my distaste for him, but I seriously doubt...

    Aug 14, 2020 at 7:43 PM
  19. FGG rated all to gain's post Agree in the thread 2020 US Presidential Election.

    To add, I would say that it isn't democracy either.

    Aug 14, 2020 at 6:41 PM
  20. FGG liked GlennS's post in the thread 2020 US Presidential Election.

    People tend to gravitate towards dualistic thinking. Good/bad. Black hat/white hat. This is a childish oversimplification of how the world...

    Aug 14, 2020 at 6:40 PM
  21. FGG liked serendipity1996's post in the thread Suicidal.

    There is no good excuse for audiologists to ignore EHF testing. This article from 2017, 'Benefits of Extended High-Frequency Audiometry for...

    Aug 14, 2020 at 6:10 PM
  22. FGG liked Diesel's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It's good to see Frequency is presenting how FX-322 will benefit ENT and Audiologist practices in the future. When FX-322 is commercialized, there...

    Y4T7bqA.png Aug 14, 2020 at 5:52 PM
  23. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    From what i understand (correct me if I'm wrong), a "cochlear dead region" is defined as missing significant IHCs, thus hearing aids won't help...

    Aug 14, 2020 at 4:56 PM
  24. FGG liked WillBeNimble's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They announced a delay till 2021 for data because of difficulty getting candidates due to COVID-19. You might still get a shot at being in the...

    Aug 14, 2020 at 4:54 PM
  25. FGG replied to the thread Aldosterone and Hearing.

    Aldosterone decreases as we age and some people think this is why older people are more susceptible (I will look for the link I read on this) to...

    Aug 14, 2020 at 4:06 PM
  26. FGG liked Billy_Shears's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I attempted to enroll but my NIHL and audiogram is from only three months ago. They want six months that defines 'stable'. I was told all else...

    Aug 14, 2020 at 3:40 PM
  27. FGG replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    Because it doesn't cause any hearing structures to regenerate. Otherwise you would have to say drugs like Prednisone were "hearing regeneration...

    Aug 14, 2020 at 3:38 PM
  28. FGG liked Thuan's post in the thread Aldosterone and Hearing.

    Okay, thank you. I'll try to find a good food source for potassium.

    Aug 14, 2020 at 12:28 AM
  29. FGG liked WillBeNimble's post in the thread My Posting Place.

    Yeah, evolution isn't perfect. It can be clever, but it's generally a process of "good enough". For example, the laryngeal nerve. It goes under...

    Aug 14, 2020 at 12:11 AM
  30. FGG rated tommyd87's post Agree in the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    To me this has actually got the submarine rescue written all over it again. Musk makes a claim contending that he can come up with an advanced...

    Aug 14, 2020 at 12:05 AM
  31. FGG replied to the thread Aldosterone and Hearing.

    Aminoglycosides (like Neomycin) are not toxic to the strial Na/K channels. I doubt this would help you but it could slow down the progression of...

    Aug 14, 2020 at 12:03 AM
  32. FGG replied to the thread Aldosterone and Hearing.

    I'm not taking it for any reason other than Azithrimycin is completely unique in targeting the Na/K channels of the stria vascularis (among other...

    Aug 13, 2020 at 11:36 PM
  33. FGG rated serendipity1996's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Yeah, I get you although I think it's useful to distinguish between failures and 'scams.' Failure is an inevitable risk when developing new drugs...

    Aug 13, 2020 at 11:34 PM
  34. FGG rated aot's post Friendly in the thread 2020 US Presidential Election.

    Lol. Sorry, I misread your post. :dohanimation:

    Aug 13, 2020 at 8:37 PM
  35. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Next to none considering I applied and was not asked about it and it is not on their exclusion list.

    Aug 13, 2020 at 8:31 PM
  36. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Their exclusion criteria has listed over 70 dB as an exclusion from the start (it is on their clinicaltrials.gov page). I'm not sure why that...

    Aug 13, 2020 at 8:29 PM
  37. FGG rated Jurger's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Yup, I remember we discussed this sometime ago. I always counted on a delay given that they have to follow patients 210 days and are still enrolling.

    Aug 13, 2020 at 8:25 PM
  38. FGG replied to the thread Aldosterone and Hearing.

    He's a general practitioner that the compounding pharmacy in Canada informed me is familiar with the drug and its use. He does telehealth. It's...

    Aug 13, 2020 at 8:25 PM
  39. FGG liked Christiaan's post in the thread 2020 US Presidential Election.

    This clip explains how that can be done, like creating a proportional vote system [MEDIA]

    Aug 13, 2020 at 6:27 PM
  40. FGG liked Zugzug's post in the thread 2020 US Presidential Election.

    Question: How do more parties solve the polarization problem? Doesn't it just make it worse? i.e. instead of two poles with a fair amount of...

    Aug 13, 2020 at 6:27 PM
  41. FGG rated WillBeNimble's post Agree in the thread 2020 US Presidential Election.

    If there's more parties, there's greater maneuverability between opinion blocs. So, you'd be more willing to hear arguments from those who are...

    Aug 13, 2020 at 6:27 PM
  42. FGG rated Emgee's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It’s possible that they could’ve conducted the trial with fewer people, but this would almost certainly mean that an additional phase would be...

    Aug 13, 2020 at 5:21 PM
  43. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    The ceiling effect is intuitive, if you already have near perfect word scores, it is hard to get an improvement. @Piney, are you sure they...

    Aug 13, 2020 at 5:02 PM
  44. FGG rated WillBeNimble's post Agree in the thread 2020 US Presidential Election.

    More parties are needed because it will allow us to focus on actual policies. The major issue I see is that we currently are stuck with two...

    Aug 13, 2020 at 4:07 PM
  45. FGG liked WillBeNimble's post in the thread 2020 US Presidential Election.

    I think they don't want to because it's guaranteed to cause a major fight about democratic cities vrs republican cities in the middle of a thread...

    Aug 13, 2020 at 2:43 PM
  46. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They said in their Fireside that they had a temporary pause in their enrollment but were still dosing and following already enrolled participants....

    Aug 13, 2020 at 2:40 PM
  47. FGG rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    According to the August presentation, there is "Significant enthusiasm amongst <Otolaryngology> community." So, I'm sure there is some...

    Aug 13, 2020 at 2:37 PM
  48. FGG rated Jurger's post Agree in the thread Pipeline Therapeutics.

    Better treatment capabilities will likely raise the demand for better diagnostics. Right now, being able to tell what kind of damage your cochlea...

    Aug 13, 2020 at 2:35 PM
  49. FGG replied to the thread Aldosterone and Hearing.

    If his low frequency problem was causes by hydrops, he could absolutely see that kind of dramatic improvement in low frequency hearing. Mine...

    Aug 13, 2020 at 2:19 PM
  50. FGG replied to the thread Pipeline Therapeutics.

    This is how I understand it. Tinnitus is the response of the brain to decreased auditory input (or input that is interfered with in some way) at...

    Aug 13, 2020 at 2:02 PM