FGG's Recent Activity

  1. FGG replied to the thread Challenging the Current Terminology of Hyperacusis.

    My very (apparently furiously anti leaf) neighbor just bought a super high powered leaf blower last year and she was out there with it daily. I...

    Feb 25, 2021 at 6:29 PM
  2. FGG rated Diesel's post Informative in the thread Challenging the Current Terminology of Hyperacusis.

    We've had tinnitus about the same length of time. My initial pain symptoms were similar and I noticed improvements in about the same timeframe - a...

    Feb 25, 2021 at 6:26 PM
  3. FGG rated Orions Pain's post Informative in the thread Challenging the Current Terminology of Hyperacusis.

    @FGG, I had that prickly sensation on my ear cartilage at some point. I always felt like it was a feather from my pillow poking me but when I'd...

    Feb 25, 2021 at 6:24 PM
  4. FGG rated Ed209's post Hug in the thread Coronavirus (SARS-CoV-2 / COVID-19) and Tinnitus.

    Still in hospital at the moment, Daniel.

    Feb 25, 2021 at 6:13 PM
  5. FGG rated Keith Handy's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I have skills and talents I want to use, and people I want to collaborate with, but concentrating on anything now is like walking face first into...

    Feb 25, 2021 at 5:17 PM
  6. FGG liked serendipity1996's post in the thread Challenging the Current Terminology of Hyperacusis.

    I can't pinpoint an exact moment and it was more of an intermittent thing but I would say gradually over the course of 7-8 months maybe? It tended...

    Feb 25, 2021 at 3:12 PM
  7. FGG rated Jrblovsky's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    The people who think that way are absolute imbeciles. I think of everything as a mechanical issue. Look at a car. If you have a bad sensor it goes...

    Feb 25, 2021 at 2:42 PM
  8. FGG rated Matchbox's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    If FX-322 works for hearing loss, tinnitus & hyperacusis... This is Nobel Prize or whatever the equivalent is for Applied Sciences.

    Feb 25, 2021 at 2:41 PM
  9. FGG rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    The fact of the matter is: "Working beyond a reasonable doubt" is displayed by statistical significant and clinically meaningful improvements in...

    Feb 25, 2021 at 2:41 PM
  10. FGG rated Zugzug's post Hug in the thread Challenging the Current Terminology of Hyperacusis.

    @Aaron91 and @serendipity1996: I want to say that I think you two are very bright and good-hearted people. I don't regret what I wrote, but I...

    Feb 25, 2021 at 2:38 PM
  11. FGG replied to the thread Challenging the Current Terminology of Hyperacusis.

    Are you talking about my initial pain symptoms 2 years ago or what I have now? How long before you noticed improvements?

    Feb 25, 2021 at 2:37 PM
  12. FGG liked Zugzug's post in the thread Challenging the Current Terminology of Hyperacusis.

    That was quite the write up, but I almost completely disagree. In fact, after reading this, I am actually more convinced that the pathologies are...

    Feb 25, 2021 at 2:33 PM
  13. FGG liked Zugzug's post in the thread Challenging the Current Terminology of Hyperacusis.

    It's not actually vague. I also don't think it's hard to picture a pencil falling off the table being as loud as a hammer and making one super...

    Feb 25, 2021 at 2:33 PM
  14. FGG liked Prestigeknows's post in the thread Ringing in Ears After Whiplash Caused by Sneezing.

    Just an update: My hearing has returned 90%. Thank you to everyone that helped me along this stressful week. I’m soon to have it all back!

    Feb 25, 2021 at 5:40 AM
  15. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I wish you could pop up with this anecdote anytime people try to say tinnitus is brain damage/stuck in the brain and fixing the underlying cause...

    Feb 25, 2021 at 4:47 AM
  16. FGG liked Jrblovsky's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Restore hearing. Tinnitus goes away. I'm living proof. When my thresholds recovered the tinnitus went to almost non existent. Thresholds went...

    Feb 25, 2021 at 3:32 AM
  17. FGG liked Orions Pain's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It’s okay for people to engage in conversation and ask questions! This entire thread is what if’s with some facts sprinkled in lol.

    Feb 25, 2021 at 3:11 AM
  18. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Probably not necessary. It's an anti seizure drug (so crosses BBB easily) and a small molecule. It probably crosses the blood cochlear barrier...

    Feb 25, 2021 at 3:07 AM
  19. FGG liked serendipity1996's post in the thread Challenging the Current Terminology of Hyperacusis.

    We've mulled this over quite a lot and I think it's a very worthy topic of discussion. On the one hand, I do think it is instructive to stratify...

    Feb 25, 2021 at 2:58 AM
  20. FGG replied to the thread Challenging the Current Terminology of Hyperacusis.

    How long did it take to go away?

    Feb 25, 2021 at 2:58 AM
  21. FGG liked serendipity1996's post in the thread Challenging the Current Terminology of Hyperacusis.

    Just to add, I also used to experience the needle prick feelings on the outside of my ears, like around the cartilage and pinna. I also used to...

    Feb 25, 2021 at 2:57 AM
  22. FGG replied to the thread Challenging the Current Terminology of Hyperacusis.

    I think it would depend on your noise exposure, no? I had a small phone speaker held up to my left ear. It wasn't very loud on my right.

    Feb 25, 2021 at 2:50 AM
  23. FGG liked Gb3's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It all depends what the data tells us. What if, what if, what if. Why don't we just wait and see.

    Feb 25, 2021 at 2:48 AM
  24. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I guess they could restart a Phase 2 trial and recruit for tinnitus specifically but that won't be necessary. If it doesn't work for hearing, it's...

    Feb 25, 2021 at 2:48 AM
  25. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    So you are thinking because of the VPA and timing the injections a week apart you won't see much of anything lower than 8 kHz? If that ends up...

    Feb 25, 2021 at 2:45 AM
  26. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Absolutely none imo. They have already shown it improves word scores and clarity regardless of audiogram. That's a way more objective metric than...

    Feb 25, 2021 at 2:33 AM
  27. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    If a doctor is willing to do it off label for you, sure.

    Feb 25, 2021 at 2:32 AM
  28. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Why would that be most likely? I truly do not believe they'd start a multi dose trial just to show it doesn't make a difference. There was...

    Feb 25, 2021 at 2:30 AM
  29. FGG rated AfroSnowman's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It will be interesting to see what this does in the extended audiograms. Just because it showed 5-10 dB at 8 kHz, which was its apparent limit in...

    Feb 25, 2021 at 2:18 AM
  30. FGG liked Diesel's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They have a patent-pending for using their PCA approach to restore hair follicle cells. According to Langer, they have "10 other" opportunities...

    Feb 25, 2021 at 1:24 AM
  31. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Probably. That's how it's done with Luxturna.

    Feb 25, 2021 at 1:24 AM
  32. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They mentioned cartilage before, too. Once they get a blockbuster drug approved, they can fund multiple studies simultaneously. Look at Sarepta,...

    Feb 25, 2021 at 1:14 AM
  33. FGG rated Steph1710's post Informative in the thread Be Honest. Do You Still Enjoy Life?.

    I had an X-ray done last year, when it first happened, but they didn’t find anything. I’m beginning to think it may be heart related. Everyone on...

    Feb 25, 2021 at 12:03 AM
  34. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It only suggests it may not put people in the cochlear implant range at normal hearing. It doesn't at all mean the cap is at 5-10 dB.

    Feb 24, 2021 at 11:57 PM
  35. FGG rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Yep. Only improvements were at 8 kHz with a single dose. And it was by 4 patients that received FX-322. With multiple doses, patients may see...

    Feb 24, 2021 at 11:55 PM
  36. FGG liked Jrblovsky's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    This would be just another reason for more low cost options to come into play. With deregulation occurring for over the counter hearing aids the...

    Feb 24, 2021 at 11:54 PM
  37. FGG liked Keith Handy's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Basically the exact opposite of a snake oil salesman, which is exactly what we want to see/hear.

    Feb 24, 2021 at 11:46 PM
  38. FGG liked serendipity1996's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I also reckon that he probably necessarily has to be quite cautious in these sorts of interviews anyway e.g. not hyping up timelines too much etc....

    Feb 24, 2021 at 11:28 PM
  39. FGG liked Matchbox's post in the thread Tinnitus Down to 1/10 — Eating 8 Bananas a Day.

    Just had 3 bananas, will have 3 later. Either this breaks my tinnitus or my toilet.

    Feb 24, 2021 at 11:22 PM
  40. FGG replied to the thread Is the Cause of Your Tinnitus UNRELATED to Hearing Loss or Acoustic Trauma?.

    Mine is from hearing loss due to high dose Macrolide antibiotics.

    Feb 24, 2021 at 11:09 PM
  41. FGG replied to the thread Is the Cause of Your Tinnitus UNRELATED to Hearing Loss or Acoustic Trauma?.

    Have they ruled out perilymph fistula in your case?

    Feb 24, 2021 at 11:08 PM
  42. FGG liked Jrblovsky's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Regardless you still have a device to purchase and maintain. The power level doesn't really matter. It will still break and cost hundreds of...

    Feb 24, 2021 at 10:58 PM
  43. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Thanks. A lot of people probably read the comments and don't go back and listen or read the interview on their own.

    Feb 24, 2021 at 10:58 PM
  44. FGG liked Jcmc's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    “We don't see FX 322 eliminating hearing aids. We actually see it... it could potentially be used in combination. You might have a subject that...

    Feb 24, 2021 at 10:57 PM
  45. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    If, as suggested in the interview @serendipity1996 posted, FX-322 could put some CI candidates in the hearing aid range (and potentially get rid...

    Feb 24, 2021 at 10:39 PM
  46. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    If you listen to the interview, he was talking about people close to the cochlear implant range. Most people aren't in that range and the ones...

    Feb 24, 2021 at 10:01 PM
  47. FGG liked kingsfan's status.

    Out of bananas brb

    Feb 24, 2021 at 9:50 PM
  48. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    He was talking about the cochlear implant population. He said people in the "hearing aid range" could potentially be normal / hearing aid free but...

    Feb 24, 2021 at 9:46 PM
  49. FGG replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Agree. Without tone matching tinnitus frequencies first, it's definitely not going to be universally effective.

    Feb 24, 2021 at 9:33 PM
  50. FGG rated Keith Handy's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I'm betting that the extended audiogram will be the star performer in this round of trials. Tinnitus might be hit and miss, especially if people's...

    Feb 24, 2021 at 9:33 PM