Nick47's Recent Activity

  1. Nick47 rated EDDTEKK's post Useful in the thread Tinnitology and Dr. Abraham Shulman.

    Hi once I do wonder why dr shullmann didn’t mention the Gabapentin...

    Aug 16, 2022 at 10:43 PM
  2. Nick47 replied to the thread Abraham Shulman Tinnitus Protocol (Clonazepam Plus Gabapentin).

    The worst thing about Shulman's protocol is he doesn't mention an exit strategy.

    Aug 16, 2022 at 10:39 PM
  3. Nick47 rated Padraigh Griffin's post Informative in the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    Not sure if this was posted before, but here is a chart summarising Phase 1 Results that is easy to digest. I guess the ‘hope’ is that steep...

    upload_2022-8-16_21-34-44.jpeg Aug 16, 2022 at 10:16 PM
  4. Nick47 replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    Was it 30% response rate or 30% reduction in symptoms? I thought the former was indicated.

    Aug 16, 2022 at 10:15 PM
  5. Nick47 replied to the thread Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator.

    I will have a listen. From what I gather there is frustration as there have been no updates in the last 2 years.

    Aug 16, 2022 at 10:13 PM
  6. Nick47 replied to the thread Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator.

    Yes I saw that, but I took it as a pacifying type throwaway comment.

    Aug 16, 2022 at 10:02 PM
  7. Nick47 replied to the thread Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator.

    Thanks for the detailed reply. Is this reformulated version being specifically done with the aim of having a tinnitus treatment available at the...

    Aug 16, 2022 at 9:42 PM
  8. Nick47 rated Padraigh Griffin's post Informative in the thread Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator.

    That is exactly the hope, however, I don’t agree with you as regards Clinical Trials. First Target equals primary efficacy of Focal Epilepsy and...

    Aug 16, 2022 at 9:40 PM
  9. Nick47 replied to the thread Xenon Pharmaceuticals' XEN1101 — Kv7 Potassium Channel Modulator.

    Just so I'm clear on this, is the XEN1101 trial being followed optimistically due to its similar chemical action to Trobalt and therefore people...

    Aug 16, 2022 at 8:35 PM
  10. Nick47 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    @RingingBrother, again it's only my understanding and correct me if I'm wrong, but both target inner hair cells. The difference between them is...

    Aug 16, 2022 at 8:58 AM
  11. Nick47 rated BrysonKingMe's post Funny in the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    200 dB. They blast the tinnitus out of you.

    Aug 16, 2022 at 8:54 AM
  12. Nick47 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    From what I understood of the animal models, it was inner hair cells. We all know this is going to fail, why do we get our hopes up every time?

    Aug 15, 2022 at 9:28 PM
  13. Nick47 replied to the thread Stapes Hypermobility as a Possible Cause of Hyperacusis.

    So I went for balance tests. At some point they used a vibrating device pushed into the ear. They then made the comment.

    Aug 15, 2022 at 8:05 PM
  14. Nick47 replied to the thread Stapes Hypermobility as a Possible Cause of Hyperacusis.

    I have just been diagnosed with middle ear hypermobility today. I also have reactive tinnitus and hyperacusis.

    Aug 15, 2022 at 6:54 PM
  15. Nick47 replied to the thread Cognitive Behavioral Therapy.

    Seems in Britain CBT is not widely available on the NHS and is something you now need to spend thousands on privately. The silence and blank looks...

    Aug 15, 2022 at 5:30 PM
  16. Nick47 rated Josh59's post Good Question in the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    Hello, Does anyone here know the volume (decibel) of the earbud during treatment? I ask because I have somatosensory modulated tinnitus that I...

    Aug 15, 2022 at 11:09 AM
  17. Nick47 rated LAnative's post Optimistic in the thread Otonomy OTO-313 — Treatment of Tinnitus.

    I put most of my stock in OTO-413. I look at it very simply: Shotgun bang, nerves fried, tinnitus starts. Heal nerves, tinnitus ends. Looking...

    Aug 14, 2022 at 12:15 PM
  18. Nick47 replied to the thread Suppressive Effects of Goshajinkigan on Tinnitus.

    Any results from people, good or bad?

    Aug 14, 2022 at 10:06 AM
  19. Nick47 replied to the thread Centrophenoxine (Meclofenoxate) for Tinnitus?.

    Thanks for letting us know. Too many people do not report what does not work. Appreciated.

    Aug 13, 2022 at 3:49 PM
  20. Nick47 replied to the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    @Padraigh Griffin, call me negative but I think that is a bad sign! Small groups can give better results. What happened to the other 300? Was it...

    Aug 11, 2022 at 4:57 PM
  21. Nick47 replied to the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    So it's completed, however we don't know the results. Good surveillance though! They enrolled 100 people, for some reason I had 400 people in my...

    Aug 11, 2022 at 4:01 PM
  22. Nick47 rated InNeedOfHelp's post Winner in the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    We can speculate if we want because... Study completed! There are some people walking around on Mother Earth that perhaps now have the knowledge...

    Aug 11, 2022 at 3:59 PM
  23. Nick47 replied to the thread New University of Michigan Tinnitus Discovery — Signal Timing.

    Impossible to answer. How can we speculate without Phase 2 trial data?

    Aug 11, 2022 at 1:36 PM
  24. Nick47 rated EkkoMusic's post Good Question in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    But did we ever get evidence that extended high frequency thresholds actually improved via an EHF audiogram? Or is this just affecting synapses in...

    Aug 10, 2022
  25. Nick47 replied to the thread The 'Love Hormone' (Oxytocin) May Quiet Tinnitus.

    It's certainly odd. Why change the parameters that made Phase 1 successful?

    Aug 10, 2022
  26. Nick47 replied to the thread Please Don't Say There's No Cure for Tinnitus.

    What symptoms did you get? When did you get infected?

    Aug 10, 2022
  27. Nick47 rated DimLeb's post Agree in the thread Hough Ear Institute's Hair Cell Regeneration Project.

    I don't really understand how this is big news. Maybe I read it wrong, but are they just starting out to find therapies for hearing loss? I get...

    Aug 10, 2022
  28. Nick47 replied to the thread Otonomy OTO-413 — Treatment of Hidden Hearing Loss.

    Only highly significant Phase 2 results for OTO-413, published on time, will save Otonomy. Once burned, investors will take a lot to return.

    Aug 10, 2022