Tinnex (Caroverine)

Discussion in 'Treatments' started by Markku, Mar 11, 2011.

    1. Mentos

      Mentos Member Benefactor

      Location:
      Cracow, Poland
      Tinnitus Since:
      03/2015
      Cause of Tinnitus:
      Noise induced, loud rock concert
      Calmaspray contains caroverine, you can give it a try. I know a guy from Polish tinnitus forum who claims it soften his T.
       
      • Like Like x 1
    2. Niel S.
      Badass

      Niel S. Member

      Location:
      Belgium
      Tinnitus Since:
      Jan 2018
      Cause of Tinnitus:
      Unknown
      How does he know his t softened because of the caroverine. Sometimes t gets less loud over time.
       
      • Good Question Good Question x 1
    3. Quiet please
      Balanced

      Quiet please Member Benefactor

      Location:
      Westchester County, NY
      Tinnitus Since:
      May 2008
      Cause of Tinnitus:
      Cochlear Endolymphatic Hydrops/Hearing loss
      I’ve just recently heard about the drug Caroverine. It's been around a long time apparently. Has anyone heard of it and or used it in the USA? It’s primarily used in India (known as Tinnex) & a few European countries. It comes in pill and injection form.

      Like all of us, I’ve seen so many doctors in the US and not ONE has ever even mentioned this medicine. Any thoughts?
       
      • Good Question Good Question x 1
    4. Pleasure_Paulie

      Pleasure_Paulie Member

      Location:
      Australia
      Tinnitus Since:
      06/2016
      Cause of Tinnitus:
      Noise or maybe... unicorns!
      Read the rest of the thread, it’s only 6 pages.

      People have tried it with no success. If it was a viable treatment we would certainly know about it thus doctors don’t know about it.
       
    5. Quiet please
      Balanced

      Quiet please Member Benefactor

      Location:
      Westchester County, NY
      Tinnitus Since:
      May 2008
      Cause of Tinnitus:
      Cochlear Endolymphatic Hydrops/Hearing loss
      @Pleasure_Paulie,
      My recent post was merged into this thread. I hadn’t seen it previously. I’ve read it now.
      I guess I’ll ask my doctor about it. Thank you.
       
    6. Frédéric

      Frédéric Member Podcast Patron Benefactor Advocate

      Location:
      Marseille, France
      Tinnitus Since:
      11/19/2012
      Cause of Tinnitus:
      acoustic trauma
      Randomised Controlled Clinical Study of Injection Caroverine and Ginkgo Biloba Extract in Cochlear Synaptic Tinnitus

      Abstract

      Tinnitus, also known as phantom auditory perception, is an annoying symptom and 13–17% of population reports bothersome tinnitus. Cochlear synaptic tinnitus is the most common type. Many treatments have been tried but none is yet considered to be well established. To evaluate effect of Inj.Caroverine and Ginkgo Biloba extract in cochlear synaptic tinnitus in terms of improving tinnitus grading, tinnitus matching and quality of life of patient. It is Randomised controlled study, conducted in department of ENT, on 86 patients, who met inclusion criteria, divided into 4 groups. Gr1—Inj Caroverin, Gr2—Inj Placebo, Gr3—Ginkgo Biloba extract, Gr4—Placebo as extract. A single dose infusion of caroverine immediately improves tinnitus grading and matching and provides immediate relief in reducing severity of tinnitus in 54.54% cases but improvement was not sustained in caroverine group at 3 month and 6 month follow-up after infusion. Ginkgo biloba also is effective in improving tinnitus grading and matching in 31.8% cases and improvement was sustained in ginkgo biloba group even after 3 month of cessation of treatment i.e. at 6 month follow-up. It is suggested that Inj.Caroverine as intravenous infusion should be given in severe cases of tinnitus to reduce its severity immediately and then patient should be put on Tab.Ginkgo biloba for a period of 3 months to provide sustained and long lasting relief. Thus combination therapy of Inj.Caroverin and Tab.Ginkgo Biloba, appropriately tailored to the need of patient will provide better results in greater majority of patients.

      Source: https://link.springer.com/article/10.1007/s12070-019-01655-5
       
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    7. Backpacker

      Backpacker Member

      Tinnitus Since:
      2018
      Cause of Tinnitus:
      SSHL
      @Sironketchup
      You said in another thread you were in Bad Arolsen. One doctor told me they gave Caroverine there but I don't know if it's true. So I wanted to ask you. Do they give Caroverine infusions there? I know many people say it does not help, some say it maybe helps a little bit, so I'm curious.
       
    8. Frédéric

      Frédéric Member Podcast Patron Benefactor Advocate

      Location:
      Marseille, France
      Tinnitus Since:
      11/19/2012
      Cause of Tinnitus:
      acoustic trauma
      Well, no information about duration of tinnitus, no specific test like TFI or THI.

      I wonder what a tinnitus matching improvement is.

      P-values are > and not <.

      Finally there is no reference (n°21 missing) about the study led in Austria by Ehrenberg, whereas an Austrian clinic told me that its clinical study of caroverine had been withdrawn.

      CLINICAL STUDY OF EFFECTS OF INJ. CAROVERINE AND GINKGO BILOBA EXTRACT IN COCHLEAR SYNAPTIC TINNITUS
       

      Attached Files:

    9. Cbush

      Cbush Member

      Tinnitus Since:
      2018
      Cause of Tinnitus:
      Age loud noise
      The above report seems to say CAROVERINE AND GINKGO BILOBA are effective. Or did I read it wrong?
       

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