Frequency Therapeutics — Hearing Loss Regeneration

Discussion in 'Research News' started by RB2014, Dec 8, 2016.

    1. Flamingo1

      Flamingo1 Member Benefactor

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      Biotechs are incredibly risky. They can shoot up or down 300-400% overnight! Very volatile. With that being said, I still plan to pick up more shares of Frequency Therapeutics before they announce their phase 2 results. Been following them for a long time and trust their leadership.
       
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    2. Flamingo1

      Flamingo1 Member Benefactor

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      Whatever DID happen to that guy? Maybe he got bitten by the sea anemone he was trying to shove down his ears. LOL.
       
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    3. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      It was probably another user on this site with an alt just being silly.
       
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    4. Bartoli

      Bartoli Member

      Tinnitus Since:
      2009,worsened 2019
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      16 kHz is pretty impressive. I'm only 33 and my good ear tops out at 14 kHz. The bad at 12 kHz.

      No hearing loss. Good speech in noise recognition. Don't think about your tinnitus too much. Learn to live with it.

      What a joke.
       
    5. Ctw
      Tired

      Ctw Member

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      Great beard BTW!!
       
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    6. dustyoffski

      dustyoffski Member

      Tinnitus Since:
      2014
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      Let's hope it pans out, and it actually can help people. It's nice to see slightly promising results, but this isn't the first drug for hearing loss or tinnitus that's made it to phase 2. Statistically speaking this is still almost definitely going to fail.
       
    7. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

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      Hi,
      Could you please give an example of a small molecule drug trialed in the past that failed.
      Also, any drug for “hearing loss” be it stem cells or not a small molecule drug... anything.

      Thanks.
       
    8. Jukka

      Jukka Member Podcast Patron Benefactor

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      Or any drug trialed which have had FDA fast tracking status...
       
    9. ajc

      ajc Member Hall of Fame

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      AM-101 (Keyzilen) was given Fast Track status, and it failed.

      There's actually loads of drugs that have been given Fast Track Status and they failed, many Alzheimer's drugs too.
       
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    10. Lucifer

      Lucifer Member Podcast Patron Benefactor Hall of Fame

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      FX-322 seems like the real deal. There’s also Audion/Regain as well.
       
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    11. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

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      Hearing regeneration ajc, not drugs in general.
      If you know of examples of failed drugs for hearing regeneration, please educate me.
      Tnx.
       
    12. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

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      No , not any drug which have had “ FDAfast tracking status”, your words.

      any drug concerning “ hearing regeneration”

      specifically hearing regeneration, be it small molecule or “ any drug” including stem cells for “ hearing regeneration “

      that’s clear, yes?
      Thanks in advance
       
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    13. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

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      I'm not going to let the cynics and negativity mongers shit on this thread and this technology.

      Go FX-322, kick ass and grow some hairs in phase 2.
      Fingers crossed.

      Your devoted fan and groupie,
      Daniel
       
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    14. John Queen

      John Queen Member

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      No, it didn't fail. They just narrowed (or changed) the indications and are continuing the approval process. This is a quite recent video that the company posted.

      Auris Medical Keyzilen® (AM-101) Testimonial
       
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    15. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      I don't take orders from beta-males.
       
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    16. ajc

      ajc Member Hall of Fame

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      Wrong. It REALLY failed TWICE in phase 3 trials, and they always continued by changing the outcome endpoints.

      Basically they are on life support, trying to make the phase 3 work a THIRD time.
       
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    17. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      LOL this is making some investment bankers really pissed off. MUH INVESTMENTS
       
    18. Bartoli

      Bartoli Member

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      Qué? I meant that was the advice I was given once I got my hearing tested.
       
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    19. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      Oops, my apologies. I thought you were saying I was a joke.
       
    20. Bartoli

      Bartoli Member

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      You're not a joke @JohnAdams, you just have long toes is all.
       
    21. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      Yeah my toes look like fingers.
       
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    22. antonio77

      antonio77 Member

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      Tinnitus occurs due to the hyperactivity of neurons, right? Now the question is: does only damage to hair cells produce hyperactivity in neurons?
       
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    23. Mathieulh
      No Mood

      Mathieulh Member Benefactor

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      I just watched the video, this is 100% a paid professional actor.
       
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    24. ChrisBoyMonkey

      ChrisBoyMonkey Member

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      There's research that just loud sounds with little to no hearing loss alone might be enough to trigger it. Dr. Shore looks into this in her research.
       
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    25. JohnAdams
      Festive

      JohnAdams Member Benefactor Hall of Fame

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      Right, people go to college to learn how to talk like this in front of cameras. I know because when I was in grad school I paid my tuition by working in the college's TV Film Radio degree program.
       
    26. Rb86

      Rb86 Member

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      That's possible. It's also possible it's not. You don't know.

      Honestly, the fact that it all went away in a year's time essentially doesn't say too much for the drug... but it's refreshing to see someone claim actual real result.s
       
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    27. ChrisBoyMonkey

      ChrisBoyMonkey Member

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      Scripted, yes. Paid actor, I don't think so.
       
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    28. Mathieulh
      No Mood

      Mathieulh Member Benefactor

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      Cause of Tinnitus:
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      Actually, I do know, I recognize a professional actor when I see one, too many choreographed moves, no hesitation in the talking pattern, over exaggerated, unnatural emotions...

      This is 100% an actor and 100% scripted, and likely 100% not genuine.
       
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    29. Flamingo1

      Flamingo1 Member Benefactor

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      Just look at the 5 year price history of the Auris Medical stock, EARS, and it will be clear that they have not succeeded yet!

      https://finance.yahoo.com/quote/ears
       
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    30. Rb86

      Rb86 Member

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      I can see her read, and I can see how she emphasizes what she's saying emotionally, but that doesn't mean an actor. They could've taken someone who wanted to share their story and worked with them to do that. That could've been take 25.

      You don't know unless you have proof. Just like we don't know if the drug truly works until evidence from real trials comes out.
       
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