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Sorry but that sounds like total bollocks. "Flupirtine exhibits efficacy on all four subunits, Kv7.2, Kv7.3, Kv7.4 and Kv7.5, with an apparent...
Very informative podcast! My only concern was how far away OTO-6XX seems to be, but I've recently started wondering if hair cells have been over...
Interesting, thanks for sharing! So if my audiogram shows I have a hearing loss in some of the high frequencies, it's likely that it's mainly my...
I truly believe this is what actually causes the majority of issues. It isn't our resolution, it's our bandwidth that's screwed and, if...
I believe there is a test audiologists use called an Auditory Brainstem Response, which can test retro-cochlear and brainstem involvement in...
I don't have trouble with pure tone just complex sound. There is certain kind of KV 3 potassium ion channel involved in sound layering, esp...
That's a really good point. I have completely symmetric bilateral tinnitus. Both of my two different tones are in both ears at the same volume....
So why does too much noise exposure lead to a setback in hyperacusis sufferers?
Nobody knows for sure if it will work for hyperacusis. Because we truly don`t know what the root cause of hyperacusis is at this time. But there...
@weab00 I'll move this to this thread where it's more relevant. As per the research and the models arising out of it I assume noise is causing a...
I've read this several times. I understand it bit better every time so I'll see I I can break it down a bit. Unmyelinated type II afferent...
Great post, @100Hz. I've read this several times now over the last few days and I'm still trying to gather my own thoughts, but thought I'd share...
For those who are concerned by this specific subtype of tinnitus : clocking tinnitus and migraine. Clocking tinnitus: An audiology symptom of...
Reduced sound-evoked and resting-state BOLD fMRI connectivity in tinnitus Benedikt Hofmeier, Stephan Wolpert, Ebrahim Saad Aldamer, Moritz Walter,...
http://www.sensorion-pharma.com/images/press-release/20181221-PR-SENS401-OtoNeuroJournal.pdf The Sensorion pre-clinical team tested the efficacy...
I agree @Vinnitus, I've done a lot of research on this - as I believe many of us do - and believe the most likely scenario for me is nerve damage....
You seem smart and relatively interested in my case, so I'll upload other tests I've had for you to look at. I had an OAE (Otoacoustic Emissions...
All this is blowing my mind. Proof again post hearing loss, the touch nerves go hyper, regrow, and actually gain some form of auditory input. But...
Yeah, always better when I wake up. Thought maybe it was the brain still not fully activ, but I also think you are on to something. Found this: A...
more details: https://www.academia.edu/421675/Contributions_of_Kv3_Channels_to_Neuronal_Excitability
I found this- Pharmacological modulation of Kv3.1 potassium currents Maile R. Brown1, Charles H. Large2, Giuseppe Alvaro2, Leonard K. Kaczmarek1...
Hi, I do want this thread to continue and to inject fuel into it. I have consulted two doctors who claim to have treated thousands of tinnitus...
They got back to me and said this "We will investigate. I forwarded the info to one of our partnering researchers who does animal studies which is...
Except the ringing is caused by the middle ear, it is not an actual phantom sound. I have both subjective and objective tinnitus. The subjective...
Hi Rog sorry Im late responding to your message but Kimbo pretty much hit the nail on the head with his response.Its been well established that...
I looked through some of the channels. KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating. Solé...
Jazz...this is an incredible article! Sort of the "go to" for a comprehensive, technical, "how does it all work" for hearing and it's relationship...
guys i think this worth reading http://medicalxpress.com/news/2015-07-gene-therapy-deaf-mice.html Using gene therapy, researchers at Boston...
@chronicburn @Sjtof @Sound Wave @just1morething This is one of the most comprehensive articles about Tinnitus I have come across, and I want...
@benryu - did you mean this article? (I dont see K channels). I did see mention on Katp channel involved in another article you linked - are...
Nope I meant this one : http://www.sciencedirect.com/science/article/pii/S1359644605035427 But didn't you find what you were looking for in other...
I can relate to this so well. Its like you are describing my own symptoms in a very detailed manner. I stated in a post @Sjtof that my big toes...
