Search Results for Query: sensori

Key takeaways: Currently working towards an IND submission in Q1 2025. Following a successful submission, clinical testing can begin in 2025....

Another company: Bsense Announces the Clinical Candidate Nomination of BSEN760, a Novel Dual Kv7.2/3 and TRPV1 Modulator, to Unlock a New...

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I'm excited about this because, if true, it's the only time any therapy has been able to target hair cells. If they establish a working vehicle,...

"OHC vesicle exocytosis is triggered by the influx of Ca2+ through class-D L-type Ca2+ channels (CaV1.3) clustered at each active zone." Calcium...

Hey, in layman’s terms, what does this mean?

I have a bottle of Natural Factors NAC that arrived a couple of days ago but I wonder if I should take it. I've seen reports of it causing...

I don't know where else to post this but here's another paper that came out this month, that says anterior cingulate cortex plays a big role in...

Animal study on electrical activation of the cortex after hearing loss induced tinnitus. → Cortical Surface Plasticity Promotes Map Remodeling...

@Pinhead, I'm sorry for your suffering and the bad progression of your symptoms. Regarding reactivity, I think the DCN somatic "miswiring" goes...

Possibly relevant to this discussion: → Sensory gating functions of the auditory thalamus: adaptation and modulations through noise-exposure and...

On the German version of Wikipedia the following is written: Of particular note is the ototoxicity (damage to the inner ear) of locally and...

I have not commented on this thread much recently but if all goes well, I estimate approval will be before July 2024. What we don't know is if...

This already tells me you are just moaning without actually having read or researched the matter at all. University of Michigan has made a...

Check this out: In Pursuit of Hair Cell Regeneration Through Collaboration Hearing Health Foundation’s Hearing Restoration Project (HRP) is the...

Have any studies or research been carried out into a possible link between increased Glutamate levels via sensory pathways other than sound...

My tinnitus officially began in 1980, I remember the day: I was shopping in JCPenney's with my mom and began to hear this high-pitched whine. It...

They did matching level when I went through clinical trials years ago. It's then matching level - sensory level to estimate the volume. Some of...

I attached two papers. The first one covers the inferior colliculus, saying that the Kv7 channels (2 and 3) are present there and can be modulated...

Hmmm, perhaps this could also help people with tinnitus? Dr. De Ridder believes that (neuropathic) pain and tinnitus share similar...

Michigan Medicine: Study shows promising treatment for tinnitus “This study paves the way for the use of personalized, bi-sensory stimulation as...

I like the sound of that timeline. I wonder what makes you think approval will take place in July 2024?

There are no NaV1.8 blockers on the market at this moment as I am aware. I'm no scientist but the pain/tinnitus comparison is from...

A study comparing EEG recordings of 3 distinct groups shows commonalities and differences in various brain regions between tinnitus and pain...

@InNeedOfHelp, it sounds crazy. Like where is the proof of concept or scientific findings to support this?

Thank you for sharing! Wow, encouraging to know that even though you had multiple tones that oscillated, you still saw/heard notable decrease and...

Not diagnosed but I have strongly suspected for a long time that I’m somewhere on the autism spectrum. I also have severe mental illness (general...

Multi tone, most annoying is oscillatory stuff that's predominately left but also centralized and in the 12 kHz range. For me reactivity is a...

Yes, more specifically sensory gating.

There is no mystery as to why not all noise-induced hearing loss leads to tinnitus. First of all, let's think about noise. Noise exposure has...

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically AudioCure Pharma...

Hello, all. Long time occasional lurker, first time poster, going to jump right into it. (My apologies in advance if I break any implicit...

When I describe that the ringing has faded, it means that I do not experience any emotional reaction to the tinnitus I experience. I believe this...

This might go some way in explaining - both cannabis and nicotine are shown to affect the sensory gating process: Alterations of auditory...

Pretty much sums up everything I have and feel on a daily basis. Trying to get any sort of help for it has been a waste of time. Pills or CBT,...

I'm glad you're habituating. I dislike when people describe that the ringing is gone and that isn't actually the case though. It's important to...

Yeah. I feel like my other symptoms just make dealing with severe tinnitus worse. Funnily enough, I did some researching a while back and found...

I understand where you're coming from, and I truly empathize with that. However, I would still say that the ringing is out of my perception about...

I guess we will never know but this is the conclusion from one of the head neurologists at the London Neurological Hospital. His view is the...

I noted the same thing with the control group. Just a superficial glance at the scatter chart doesn't seem to indicate a trend of worsening with...

Prof. McNaughton gave a recent interview to an online audiologist. He summarised tinnitus to chronic neuropathic pain, saying that tinnitus is...

Has the Guanfacine affected your tinnitus at all so far? I'm thinking about trying it myself.

This lines up with FREQ's age-related hearing loss trial, they did not see a robust response in that trial which also suggests age-related hearing...

Kv 7.4 cells are present in the ear so Kv 7.4 targeted medicine can directly attach to the desired location. That's why it can be done with local...

@ECP, perhaps try the Sukie Baxter meditation for chronic pain on YouTube: [MEDIA] There is a little eye movement exercise at some point. I...

Ha, indeed! Just shows that sometimes we can't help or save ourselves. It is one of those things that maybe requires constant reinforcement....

Thanks, I have done all the Sukie Baxter videos before. She is very good, but her methods alone have not been entirely effective for me. White...