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They don't. No. They are much better at low frequency sound - e.g., airplane engines.

I would change "detect" to "infer". There is a fairly standard approach used to attempt to infer tinnitus, but what isn't clear how good that...

I would have loved to see them live. Wrong continent and a little too young though... Would also love to know what their next album would have...

I believe the reduction during treatment was more like 8 dB (assuming we are talking about the 2018 paper and not something more recent - I...

@SecretDoubleCat My apologizes for all of the off-topic posts. I feel like I owe you a direct response. I went back and read your original post...

Not sure how to quote a quote so this will have to do. Even if it is MEEI, there is no link to the study. (I'm guessing it is...

No, in fact I said and In the present context, the point was that I think there are good reasons that this is not evidence that IGF-1 is "very...

I'm not sure why you are so defensive about this. I am in academia so I am well aware (painfully in fact) of peer review. My papers are subject...

I should have been clearer. The null here is that there is no difference between IGF and Dex though as I said, I think things are stacked a bit...

Pure tone audiometry is not "inaccurate". It accurately measures thresholds at a specific set of frequencies though there is a +- 5 dB test/retest...

I'm not aware of any studies showing that anything is "very effective" for SSHL. Even the evidence for steroids is mixed. Thanks for posting the...

Here is a link to the paper: Ultra-open acoustic metamaterial silencer based on Fano-like interference Here is the press release: Researchers...

In neither picture do they show the nozzle in the nose. what they are showing is the direction. You don't have to "force" it - you don't want to...

I'm not sure what the confusion is. Look at the picture that shows the "CORRECT spray angle on the right side about 1/3 of the way down the page....

https://www.fauquierent.net/etd2.htm

Yawn. Hyped headline. No new information. Phase 1 was successful, recruiting for phase 2.

This isn't something someone can just go to: "Cowen conferences are open to our institutional, venture capital, and corporate clients."...

Thanks. Well, not quite sure what distinction you have in mind. Perhaps contact during the growth period isn't necessary once growth has started...

It's also worth pointing out that, while we don't have the next paper, there's a new paper out of Albert Edge's lab that is continues work on...

I've been reading the last bit of this thread. It's remarkable how much is based on wishful thinking. You would think FX-322 is about to be...

Nothing on clinicaltrials.gov and the pdf looks a bit amateurish; nonetheless:...

Not sure why the link or paper would not 'remain published'. The journal is called "Clinical Trials" and deals with trial design and...

Med El is a manufacturer of CIs. It's like everything else - people are different, and some people improve with a CI, some experience no change,...

Go to https://www.dizziness-and-balance.com/disorders/bilat/ototoxins.html and scroll down to the section on antibiotics.

Earlier in this thread I posted about a video of a talk that Will McLean gave. The video was a bit hard to find, but it is now on YouTube: [MEDIA]

There's also good information here: https://www.dizziness-and-balance.com/disorders/bilat/ototoxic_drops.htm along with a bunch of references.

The information is given in the clinicaltrials.gov entry: The University of Arkansas.

Excellent question. You look at data from clinical trials where one group received the drug and the other the placebo and then see if the symptom...

They did a Phase 1 trial three years ago and haven't started Phase 2 so I don't think there's any reason to be particularly optimistic at the...

Some context is important here. From the comments and questions, you would think they had posted results of a large, successful Phase 2 study....

Here's an interesting talk that Will McLean gave on March 20 at a conference hosted by Sartorius. Mclean was a finalist for “The Sartorius &...

I think this is right. Presumably they have been talking to the FDA, and this is something FDA has signed off on. I also hope that they consider...

It is - is test re-test variability is +- 5dB so this is at that edge. I have seen people say that 10 dB shows a significance difference, and I...

Interesting talk/interview with David Lucchino (Frequency CEO) from the Alliance for Regenerative Medicine Conference: [MEDIA] Two interesting...

Already posted: https://www.tinnitustalk.com/threads/frequency-therapeutics-—-hearing-loss-regeneration.18889/page-40#post-326265 Since his title...

In this...

No, it's not. It seems to be about a hypothesis test that you have in mind but haven't been clear about. As far as I can tell, you have in mind a...

The number of hair cells has nothing to do with frequency range. Mice have fewer hair cells: https://link.springer.com/article/10.1007/BF00611249...

The same issues have been pointed out multiple times. If you don't understand by now, there's really no point in explaining it again. This isn't...

Regarding Frequency, all that is new is the information in slides 79-80. We already knew informally that there was some hearing recovery; we now...

So? Still not useful.

A well-designed survey would be one way to find out. A poll on this site is not a well-designed survey and won't provide any useful information.

There is no new information as far as I know. Not sure why you think that. I would think that it would be in there interest to terminate a...

Sensorion will be presenting some preclinical results at the American Neurotology Spring meetings:...

I Am not sure what this means, but phase 2 hasn't even started yet.

They haven't "switched to" diabetes. They have expanded to other areas including diabetes, muscle regeneration, and ""demyelinating diseases,...

Some news from Frequency with a (new?) chief medical officer: http://www.frequencytx.com/news-events/news-events-press-release-04-13-2018.php

It hasn't started yet so there will be no results this year. There is no information yet on how long the trial will last so we don't know when to...

No control group so we don't learn anything about how effective the treatment was.

This was already posted:...

This is basic scientific research done with extracted cochlea (i.e., it was not done in living mice). No plans are given in the paper, but...

Interesting paper with a new twist on delivering drugs to the inner ear - particularly to repair synapses and preserve spiral ganglion neurons:...

Not that I am aware of. AFAIK, Edge is no longer involved with Audion. From June 26, 2016, (Gill works for Audion) "SYNAPSE: Does the...

The statement is that individuals with 'profound' hearing loss are unlikely to have supporting cells. The threshold for profound hearing loss is...

If you guys want to talk about your specific HL profiles, could you please start a thread in support so that this thread can stay focused on...

Not that I know of. Of course, but we simply won't know any of the details until a paper is published (or until more details show up someplace else).

Very interesting talk by Jeff Karp. He talks about his lab's early research on the intestines which ends up explaining the connection to...

I posted about the actual study when it was first published:...