Alzheimer's Drug (Aducanumab) Study Gives 'Tantalising' Results

Discussion in 'Health Talk' started by Candy, Aug 31, 2016.

tinnitus forum
    1. Candy

      Candy Member Benefactor Team Awareness

      Tinnitus Since:
      06/2016
      Cause of Tinnitus:
      Unidentified
    2. undecided
      Fine

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      I imagine someone on some Alzheimer's forum reads this, gets super excited, parties, goes to bed, same shit in the morning can't remember anything about any drug, goes back to the forum, reads about the drug, gets super excit....

      Sorry, bad joke, worth posting though.
       
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    3. Sebastians

      Sebastians Member

      Tinnitus Since:
      13/10/2015
      Cause of Tinnitus:
      Guitars, loud girls and guns
      I vaguely remember reading about this stuff ;-)
      Maybe if i get alzheimer's i forget about having T!
       
    4. Vinnitus
      Bookworm

      Vinnitus Member Benefactor

      Location:
      Amsterdam
      Tinnitus Since:
      28/04/2016
      Cause of Tinnitus:
      Acoustic Trauma
      http://www.webmd.com/healthy-aging/news/20110214/hearing-loss-may-be-linked-to-alzheimers

      You might be on to something! :p

      I often see talk about habituation here where people don't notice their tinnitus for months or years on end. I guess it's explained now; it's early onset Alzheimer's. They just forgot they have it (among other things).

      I'm not so sure I want to habituate now...
       
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    5. Kane Moffat
      Badass

      Kane Moffat Member

      Location:
      Glasgow, Scotland
      Tinnitus Since:
      06/2015
      Memory problems are not really that funny to be honest, if you have some kindof hearing loss you know your memory will eventually be effected? It wont be funny then.
       
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    6. undecided
      Fine

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      I wrote a small disclaimer in the end for the sensitive ones.
      Sorry you were, uh, offended.
       
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    7. Vinnitus
      Bookworm

      Vinnitus Member Benefactor

      Location:
      Amsterdam
      Tinnitus Since:
      28/04/2016
      Cause of Tinnitus:
      Acoustic Trauma
      Going from here and the hypothesized link between hearing loss and Alzheimer's development
      It would be interesting to see the trend regarding prevalence through the ages. As far as I know, the Alzheimer prevalence is steadily increasing.
      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026476/

      Our society has become increasingly noisier the last few centuries and people on average reach a higher age, meaning they accumulate more hearing loss throughout their lifetime. Maybe this could (partly) explain the increase in Alzheimer's prevalence as a cause of death when it is indeed linked to hearing loss.

      Maybe Tinnitus in turn is some kind of chronic brain inflammation which causes our neurons to become hyperactive (inflammatory reaction) leading to earlier cell death. Cell death in turn releases free-radicals which attack other healthy cells (upon which they become hyper-excited) and may cause an ongoing chain reaction which might last for decades. This might potentially explain the worsening of Tinnitus as the inflammatory response spreads in time.

      We know noise-exposure leads to cell damage or death in the inner ear, upon which a free-radical (glutamate) is released. Maybe that's where it all starts...

      It's just me speculating of course, but it kind of makes sense to me.
       

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