Breakthrough in Human Cell Transformation Could Revolutionise Regenerative Medicine

www.bristol.ac.uk/news/2016/january/human-cell-transformation.html

Interesting times.

 

Here's some context and background from someone not involved in the project http://blog.cirm.ca.gov/2016/01/21/...ntists-morph-one-cells-identity-into-another/

If you want to start working on auditory uses, here is the website http://www.mogrify.net/

 

How many breakthroughs since à cure?

 

Wait I don't understand. So it allows you to figure out which stem cells are needed for the disease or damage you have to your body?

 

From what I understand, it is a computational model that aims to predict which biomolecular pathways need to be activated in order to get the desired cell type. Neat stuff but I'm affraid the tinnitus research community might not pick up on that just yet.

 

What do you mean? Can you explain more about what you mean about the tinnitus research community not picking up on it just yet?

 

The word "breakthrough" seems to be used a lot. (unfortunately "might" or "could help" is also used a lot in the same articles). Nevertheless I don't want to underestimate the importance of all the discoveries and work that is done.

If manipulating cells can be done with a higher level of predictability and made easier with computer software this should/could (you see: "should, could") help with regenerative medicine.
This is another discovery. http://www.medicalnewstoday.com/releases/305443.php?tw

 

If I had a nickle every time I heard the word breakthrough in the science article, I'd be well over my head in nickles.

 

Wish I was being born today, so when I'm 85, these breakthroughs might yield a few cures? (That's being optimistic!)

 

I found my personal breakthrough yesterday. I " broke through" a case of beer. That's my current cure.

 

Breakthrough in nickel accumulation!

 

Las Vegas here we come!

 

When you see studpid stuff like sound therapy getting funded kind of makes you cynical about all tinnitus research related things.

Now sound therapy is less popular then it was 10 years ago. People seem to be dicking around with ion channel modulators now.

 

I love breakthroughs....

 

Well half the people who have tinnitus have no idea what's actually causing it and when you have a little discovery like the ion channels, making it sound like that's the real reason why we having ringing in our ears, why we feel so down from it, and getting some results from clinical trials, then people are going to want to get in on that. I don't agree at all that it's the ion channels. My opinion is Nt-3 synapse re-connections would work much better in suppressing the sound of tinnitus in people's hearing. There are some companies working with that.

 

I agree with you. I think chronic tinnitus will only be cured by a regenerative medecine approach.

 

Can you tell me one at least ?

 

Decibel Therapeutics led by Charlie Liberman are doing some work with neurotrophins.
http://www.xconomy.com/boston/2015/...ibel-to-battle-hearing-loss/?single_page=true

There's a thread about it too:
https://www.tinnitustalk.com/thread...st-received-52m-in-funding.11595/#post-142856