Perampanel

Discussion in 'Treatments' started by Danny Boy, Jul 12, 2015.

    1. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      I'm hoping people will try it...You can get it in Spain. I'm trying to get it in the UK, going to see a neurologist soon.
       
    2. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      It's available in Greece as well, however at the current price (170 euros for 28 10mg pills) it's just too expensive.
       
    3. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      You do realise it's one pill a day? And trobalt would cost over 200 euros for a months supply. Let's see..
      170 Euro equals
      119.81 British Pound

      Nortriptyline costs £146.13 for a months supply.

      146.13 British Pound equals
      207.34 Euro

      Trobalt costs £159.60 for a months supply of 400mg
      159.60 British Pound equals
      226.45 Euro

      So in reality, it's cheap.
       
    4. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      I don't know if it's one pill per day.
      We just suppose it's one pill per day.
      Maybe we need the 12mg pills, those are even more expensive.
      At least I know that Trobalt does something for me, so I am willing to spend some cash.
      Perampanel on the other hand...
       
    5. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Well, it is one pill a day. I don't see why you would rather be on trobalt as it's dangerous. If perampanel works it'll be safe to use for as long as you want.
       
    6. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      I like living dangerously I suppose.
       
      • Funny Funny x 1
    7. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Why don't you just buy a months worth and try it? You'd be the first to try it for tinnitus and well, you can give us hope if it all works. Or you could buy some for me and I'll pay you and send to me. I'll of course give you something extra for your time.
       
    8. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      Well I could ask around I guess, but considering the capital controls imposed on Greece, most pharmacies are stockpiling common drugs and ignoring the more obscure ones.
      I usually buy Sabril (vigabatrin, a benzo equivalent - well, short of - and potentiator, also quite effective for tinnitus) but cant find it anywhere nowadays.
      I'll keep u posted.
       
    9. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Thank you much appreciated.
       
    10. 1MW
      No Mood

      1MW Member

      Tinnitus Since:
      2008 but cured and relapsed from benzos
      Cause of Tinnitus:
      ssnhl/benzos/unknown
      Works or not?
      Trobalt works partially.
      Methylprednisolone works 100% to me is ultra cheap but has severe side effects.
       
    11. undecided
      Breezy

      undecided Member

      Location:
      Greece
      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      Unknown.
      Well I did ask around but no pharmacist had ever heard of it (no surprise there), however they could find it on their online system and order it for me (after I make a large deposit).
      So it's a no go for me, I'm happy being a guinea pig using just retigabine.
       
    12. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Lucky! Wish I could go in and get a drug without a prescription.
       
    13. 1MW
      No Mood

      1MW Member

      Tinnitus Since:
      2008 but cured and relapsed from benzos
      Cause of Tinnitus:
      ssnhl/benzos/unknown
      In greece all drugs except of narcotics like benzos,opiods,barbiturates etc are given atypal without prescription if you pay them.
      The question is if it works
       
    14. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Well, we won't know until someone tries it. It's quite safe, so don't understand why people would rather take a dangerous drug over a safe one?
       
    15. Albertus
      Killer

      Albertus Member

      Hello , I took my first dose of Fycompa , it gave me a lot of drowsiness with what I've slept well . I'll take it for a month to see what effect it has on T. 'll report , greetings.
       
      • Like Like x 7
    16. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Awesome! Can't wait to hear if it works or not. Good luck!
       
      • Agree Agree x 1
    17. Albertus
      Killer

      Albertus Member

      Well, after 5 days of test I have not noticed absolutely no positive effect on my T. To me this does not work, I'll leave to poison the body. The only effect I have noticed is a terrible sleepiness not let you out of bed . Trobalt worked the second day feeling its effects. Antiepileptic Fycompa be very good but T is useless .
       
    18. snow86
      Surrender

      snow86 Member Benefactor

      Location:
      Germany
      Tinnitus Since:
      2006 - Extreme T since 12/2013
      Cause of Tinnitus:
      see "information" on profile page. Crippled by extreme T
      dosage?
       
    19. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      I think he's on 2mg to 4mg...The highest dose is 12mg.
       
      • Informative Informative x 1
    20. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
      I think 5 days is far too short to pass judgement. Because trobalt worked quickly doesn't mean this drug should behave the same.
       
      • Like Like x 1
    21. snow86
      Surrender

      snow86 Member Benefactor

      Location:
      Germany
      Tinnitus Since:
      2006 - Extreme T since 12/2013
      Cause of Tinnitus:
      see "information" on profile page. Crippled by extreme T
      Okay, then we both know thats too early to count it out...
      Trobalt is useless on 100mg too...400mg on other hand, does the trick sometimes. Gets you high everytime. (Just talking bout the effect)

      @Albertus
      Since you´re the only pioneer of perampanel-T-Trial, do us a favour and see what happens to your T on 10-12mg ;)

      We, the T-mankind thank you.

      But it is still hard to judge the effects of Perampanel since your system and T is/was already heavily influenced by trobalt (3x300mg, 2 out of 10 Tinnitus, what I gather from your Trobalt Posts)
       
    22. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Well, I believe he'd need to be on a higher dose...As you said trobalt is useless until you get to 400mg.
       
    23. Albertus
      Killer

      Albertus Member

      True, it may be little time and a low dose. But I've noticed that not only had no positive effect on my T , otherwise I think that alters and my peaks are frequent . Moreover drowsiness with 2mg is terrible. At work I walk through the corners dead sleep. I can not go on because my T I can not drink coffee. No ... I imagine would be a authentic zombie on 12mg. Abandonment treatment. If any of you want to try it I await your results. I have tried and have not convinced me at all.
       
      • Winner Winner x 1
    24. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Sorry to hear that. So basically it made you sleepy all the time? Trobalt did the same for me. Guess it's good for sleep?
       
    25. LetyO

      LetyO Member

      Location:
      Santa Ynez, California
      Tinnitus Since:
      12/2014
      Cause of Tinnitus:
      Anxiety/depression/medications
      I guess I'm not in the know. The last I read about your progress with Troblalt your T was 1/10. Has it returned since you have discontinued?
       
    26. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      It's never retuned to baseline ever. I'd say a 2-3 when off trobalt, on trobalt a 1-2.
       
    27. preslys

      preslys Member

      Location:
      Switzerland
      Tinnitus Since:
      05/2014
      Cause of Tinnitus:
      unknown
      same case as me
       
    28. Albertus
      Killer

      Albertus Member

      Sorry, if you want me to cut my hair and scratch me a barcode tattooed and would be a perfect guinea pig . 12mg is the maximum dose for a dangerous drug as an anti-epileptic . I invite you to try your curiosity the 12mg and 24mg too also try to see what are the effects on T ;). It is easy invite to take drugs and wait the result scared to try them yourself. Sorry but no.
       
    29. AUTHOR
      AUTHOR
      Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection

      Fycompa (perampanel) is a non-competitive AMPA receptor antagonist, which belongs to a new class of drugs to treat drug-resistant partial-onset seizures, used to treat partial onset seizures in patients with epilepsy ages 12 years and older. Side effects of Fycompa include dizziness, sleepiness, drowsiness, tiredness, fatigue, irritability, nausea, weight gain, joint pain, back pain, and problems maintaining balance. Contact your doctor if you experience serious psychiatric and behavioral side effects of Fycompa including aggression, hostility, irritability, anger, and homicidal ideation and threats. Patients should be monitored for such reactions, as well as changes in mood, behaviors,

      Starting dose of Fycompa is 2 mg taken once daily at bedtime. Patients taking anti-eleptic drugs (AEDs) should start on 4 mg of Fycompa. Dosage may be increased based on how well patients tolerate Fycompa. The maximum recommended dose is 12 mg taken once daily. Fycompa is not recommended for patients with decreased liver or kidney function, or patients on dialysis. Fycompa may decrease the effectiveness of hormonal contraceptives. Tegretol (carbamazepine), Carbatrol (carbamazepine), Equetro (carbamazepine), Trileptal (oxcarbazepine), Oxtellar XR (oxcarbazepine), Phenobarbital, and Mysoline (primidone), enzyme-inducing AEDs (phenobarbital and primidone), Rifadin (rifampin), Rifamate (rifampin and isoniazid), Rifater (rifampin, isoniazid and pyrazinamide), and St. John's Wort may interact with Fycompa. Fycompa is not recommended for use during pregnancy. It may cause fetal harm. It is not known if Fycompa passes into breast milk. Nursing mothers and their doctors should decide if the patient will take Fycompa or breastfeed. Patients should not do both. If a patient withdraws from Fycompa, there may be an increase in the frequency of seizures.


      That's nothing really compared to trobalt really. Did you take it in the day? Because it says to take it before bedtime.
       
    30. Albertus
      Killer

      Albertus Member

      I take this always at night, just before go to sleep. If with 2mg fatigue and sleepiness is terrible... i dont imagine in 12mg.
       

Share This Page