Pycnogenol May Relieve Some Types of Tinnitus

Discussion in 'Alternative Treatments and Research' started by erik, Jul 11, 2012.

tinnitus forum
    1. erik
      Breezy

      erik Manager Staff Benefactor

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012
      Cause of Tinnitus:
      Most likely hearing loss
      http://www.iherb.com/Healthy-Origins-Pycnogenol-100-mg-120-Veggie-Caps/48745

      Pycnogenol, an antioxidant plant extract derived from the bark of the French maritime pine tree, was effective in relieving tinnitus symptoms by improving blood flow in the inner ear in a recent study published in Panminerva Medica.

      In a study conducted by the Chieti-Pescara University in Italy, 82 patients between the ages of 35 and 55 with mild-to-moderate tinnitus in only one ear, while the other remains unaffected, were studied throughout a four-week period. Tinnitus in all subjects was a result of restricted blood supply to the inner ear, as measured by high resolution ultrasonography imaging of their cochlear blood flow.

      Patients were assigned to one of three groups: A, B and control. Group A consisted of 24 patients who were administered 150 mg/day of Pycnogenol®, group B consisted of 34 patients who were administered 100 mg/day of Pycnogenol®, and the control group consisted of 24 patients who received no Pycnogenol®. None of the patients had previously used medication for their tinnitus symptoms.

      At the beginning of the study, patients’ average initial systolic and diastolic blood flow velocities were 14.3 and 4.22 cm/sec in the low-dose Pycnogenol® group and 13.2 and 3.2 cm/sec in the high-dose Pycnogenol® group, indicative of insufficient blood perfusion of the ear in both groups. The study found after four weeks of treatment with Pycnogenol®, inner ear systolic and diastolic blood flow velocities in the affected ear rose to an average of 21.2 and 8.23 cm/sec in the low dose group and to 24.3 and 12.5 cm/sec in the high dose group. Not only are these results significant for the improvement of inner ear blood micro-circulation and, consequently reduction of tinnitus symptoms, but they also indicate the potentially dose-related effect of Pycnogenol® on the condition.

      The study also examined in detail the effects of Pycnogenol® on the symptoms of tinnitus. Using a Subjective Tinnitus Scale (STS) at the inception of the study, subjects were instructed to rate their symptoms from “zero" (low intensity of symptoms) to 15 (constant and severe symptoms). The initial STS average value was approximately 8.8 among patients in the Pycnogenol® group and 7.9 in the control group. After four weeks, STS scores reduced to 5.2 in the low-dose group and 3.3 in the high-dose group, demonstrating a reduction of the disturbing background noise in the effected ear. There were no significant changes within the control group.

      “The study clearly indicates Pycnogenol®’s ability to improve vascular function and restore cochlear blood perfusion, which in turn relieves the severity of tinnitus symptoms" said Gianni Belcaro, a lead researcher on the study along with his team from Irvine3 Vascular labs, Chieti-Pescara University. “The results provide further evidence of the supplement’s natural efficacy for a variety of vascular health symptoms."

      More than 50 million Americans will experience some degree of tinnitus in their lifetime, according to the American Tinnitus Association. Tinnitus is a hearing condition that causes the constant misperception of sound, including hissing, ringing and rushing noises.

      “Impaired blood flow to the ear is a common cause for tinnitus, a disturbing and very debilitating condition that can considerably impact overall health and quality of life," Belcaro said. “With few options available for treatment, this study gave us the opportunity to explore a natural solution to tinnitus symptoms and its causes."

      Pycnogenol® is distributed in North America by Natural Health Science Inc. (NHS).
       
      • Informative Informative x 1
    2. mock turtle

      mock turtle Member

      Location:
      puget sound
      Tinnitus Since:
      07/26/1992...habituated after 2 years; 11/04/11 new outbreak
      erik...thanks for the information

      very interesting study

      i wonder if pycnogenol is like niacin without all the side effects (itching skin and massive face flush etc)
       
    3. calin
      Inspired

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      hmmm... nice find erik!
       
    4. erik
      Breezy

      erik Manager Staff Benefactor

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012
      Cause of Tinnitus:
      Most likely hearing loss
      Hi Calin, it is interesting. I would like to at least try it but I need to find out if I am allergic to the pine bark it is made from. I am allergic to Juniper/cedar trees and not sure if that would also make me allergic to pine trees and pine bark. I hope not.
       
    5. DebInAustralia

      DebInAustralia Member Benefactor Team Research

      Location:
      Geelong, Victoria
      Tinnitus Since:
      30/12/13
      hey guys,

      I wanted to know if anyone actually tried taking this supplement??
       
    6. attheedgeofscience
      Uninvolved

      attheedgeofscience Member Hall of Fame

      Location:
      Denmark
      Tinnitus Since:
      Childhood
      Cause of Tinnitus:
      Head Injury
      Sure. I have used it for years - as an antioxidant, and to help my eczema. Pycnogenol is one of the most potent antioxidants available. However, since my various therapies, I no longer have eczema. And as it happens, I stopped taking Pycnogenol shortly after developing tinnitus - for other reasons. I still have piles of it at home (from PharmaNord). I can give it another go, if you want. But, it is unlikely to be of help in chronic tinnitus. I can see how it might be of help in people with vascular diseases/conditions - and perhaps preventing tinnitus from occuring in the first place. Instead, I will be discussing vitamin B12 injections in the week ahead with the doctors overseeing my treatment plan.
       
    7. nogood
      Torn

      nogood Member Benefactor

      Tinnitus Since:
      04/2014
      Cause of Tinnitus:
      ototoxicity/infection
      @attheedgeofscience i already had a shot of b12 this week.... what is the protocol for b12 injections.... current ENT doctor offered me b12 on last visit and next visit will be on 20th ..
      already taking lot of supplements as of now...
      coq10
      serratiopeptidase for sinusitis and thin the mucus
      Gingko Biloba 60 Mg+Piracetam 800 Mg+Vinpocetine 5 tablet
      fish oil
      and i have been taking b12 ( methylcobalamin) tablets on and off....
      drop me a PM or put up some information regarding the b12 injections.. thanks in advance...
       
    8. MattK

      MattK Member

      Tinnitus Since:
      2/13/2014
      Thanks for all that info, Erik. I fully believe that every possible lead is worth looking into. Taking Pycnogenol, if for no other reason, would be beneficial as it is a potent antioxidant.

      I'm glad that there are some positive reports about supplementation, as I think supplements often get a bad wrap. I think part of the problem is that people are naturally more skeptical to supplements than they are to conventional medicine. And in my opinion, a better case can be presented for natural methods (diet, exercise, nutrition, and supplements) than they can be made for conventional medicines in a lot of areas of health. And when supplements do appear to work, they often aren't given credit, and usually the person says, "I don't know for sure, but I think x supplement helped my condition"... I understand the skepticism, but then again, if I take Tylenol for a headache, and if that headache goes away, I can't necessarily prove that the Tylenol got rid of the headache rather than it is just coincidental. Furthermore, there have been times when I've had a headache when it seemed like doubling the dose of Tylenol didn't do squat... but I didn't suddenly come to the conclusion that Tylenol is no different than a placebo.

      Also, I have found that sometimes there are simply poor studies done with supplements. The most common one I see is with vitamin E. The big scare study I saw with vitamin E being linked to cancer was using dl-alpha tocopherol, which is a synthetic form of vitamin E, and even the most hardcore naturopathic researchers have said for years that there are problems with the synthetic vitamin E. Naturally, vitamin E exists in 8 different forms (4 tocopherols and 4 tocotrienols), the most common in food being d-alpha tocopherol ("dl" is synthetic and vitamin E only exists as "d" in nature).

      Another point we must remember that when one eats whole foods rich with certain types of vitamins like vitamin E, for example, they aren't just eating vitamin E alone. But naturally, there are supportive antioxidants involved, such as selenium. This stuff works as a "team", i.e. there is a difference between eating an orange with its vitamin C content and its naturally occurring bioflavonoids versus taking a straight vitamin C pill with no supporting bioflavonoids or other antioxidants. In other words, vitamins and minerals do not work independently like medication does. To do so would be like sending a quarter back out by himself to play against the opposing team without his other team members--it's not that the quarter back's position doesn't "work", but his position isn't designed to make up for the rest of his team.

      lol, well, that's my little rant. I realize some will disagree with what I'm saying, but think about this: to say that vitamins don't work, is to say that all foods are equally nutritious. The reason why some foods are considered better than others largely have to do with their vitamin and mineral content. Why would you want to eat carrots which are high in vitamin A (mainly as beta-carotene) versus eating a Twinkie? It makes no sense to say vitamins and minerals have no worth; that's basically saying all foods are created equal and there is no point in choosing healthy options.

      Ok, rant over... this seriously started off as a post more relevant to Pycnogenol, but then I have seen supplements slammed on this site so much, that I just finally had to say something, lol... oh, and just because supplements may not help with tinnitus, also doesn't mean supplements "don't work". That's like saying all the over the counter medication at Wal-Greens don't work because none of them, (acetominophen, ibuprofen, claritin, Afrin, cough drops, etc) work for tinnitus.
       
      • Agree Agree x 1
    9. ItalianMan
      Fine

      ItalianMan Member

      Tinnitus Since:
      04/2012
      In Italy it would be on the market a product called Lutegenol, a combination of luteine and pycnogenol, but it is not available at all...
       
    10. tomytl
      Grumpy

      tomytl Member Benefactor

      Tinnitus Since:
      10 Years
      Cause of Tinnitus:
      unknown
    11. demiles

      demiles Member

      Tinnitus Since:
      12/1992
      I'm going to give this a try. A recent trial of Cialis had reduced my T a significant amount so this could be a solution for me.
       
    12. BBarbara
      Curious

      BBarbara Member

      Location:
      Lisbon Portugal
      Tinnitus Since:
      3/2015
      Cause of Tinnitus:
      Stress or Acoustic trauma
      Hello! Has anyone tried pycnogenol?
       
    13. jimH
      No Mood

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
      Hi Barbara.....Yes, for years, and up to 100 mg a day. I take it because it suppose to be a powerful antioxidant. However, it never had any beneficial effect on my T.
       
    14. Danny Boy
      Cheerful

      Danny Boy Member Benefactor Hall of Fame

      Location:
      England
      Tinnitus Since:
      7/2014
      Cause of Tinnitus:
      Ear infection
      Purple corn powder has the most anthocyanins by far. Also, I recommend immortality tea as it's the healthiest tea around, also caffeine free!
       
      • Informative Informative x 1
    15. Mad maggot
      Breezy

      Mad maggot Member

      Location:
      New zealand
      Tinnitus Since:
      12/2008
      Cause of Tinnitus:
      Unknown
      ive read and heard from people who have had benefits from using pycnogenol for their T. Has anyone tried it?
       
    16. Tom Gatwick

      Tom Gatwick Member

      Tinnitus Since:
      09/2008
      Where can this be bought cheapest? So expensive everywhere...
       
    17. jimH
      No Mood

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
      If you're going to give it a try, it's worth noting that in the OP, one group was put on 100mg and the other 150mg per day. The third group received no Pycnogenol. After my first post in this thread I gave it another go by increasing my dosage from 100mg/day to 200mg/day and experienced no change in my T.

      Yeah,.. it is indeed expensive. Here are some different brands sold on the Swanson Vitamins website. You can do some additional price comparisons there if you haven't already:

      http://www.swansonvitamins.com/q?kw=pycnogenol
       
    18. buzzer

      buzzer Member

      Tinnitus Since:
      1971
      I take have taken Pycnogenol on and off for the last year and a half. Even though it says it takes a few weeks to have any results the first 3 days I took it my T almost went a way completely, then came back on the 4th day. I took it for about 60 more days but only occasionally did it seem to be milder. I have tried it on and off again since with some results, but nothing like the first 3 days. Sometimes using other varieties of white pine bark supplements. I am going to start again with a stronger dose of Pycnogenol. The main thing it did was give me hope that my T is curable since I did experience 3 days of relief for the first time in years.
       
    19. _Chris

      _Chris Member

      Location:
      Indiana
      Tinnitus Since:
      12/2015
      Cause of Tinnitus:
      medication?
      I have not tried this myself. However, I heard a positive report that I thought you might find interesting to know. I recently began seeing a therapist who has worked with some other tinnitus patients previously, to try to work on developing some better coping skills. He mentioned that two of his patients had independently discovered that they obtained some relief from pine bark extract. One of them apparently felt that their tinnitus went from a '10' to a '4'. It seems that it may take a while for the benefit to kick in, like a month or so.

      I'm afraid I don't know any additional details beyond this. This was just something that came up in conversation when we were going over medicines I take and other similar kinds of general information. It was not a recommendation. I would be interested in knowing if anyone on the forum had any luck with this one. It seems like a pretty benign supplement to try.
       
    20. GregCA
      Frustrated

      GregCA Member

      Tinnitus Since:
      03/2016
      Cause of Tinnitus:
      Otosclerosis
      Are you talking about this?
       
    21. _Chris

      _Chris Member

      Location:
      Indiana
      Tinnitus Since:
      12/2015
      Cause of Tinnitus:
      medication?
      Yes. It seems doubtful that very many people have benefited or I suppose there would be a lot more written about it here. Nevertheless I felt it might be worth contributing what I had heard.

      On reading more about it, it seems as though if it was going to provide any benefit, it would be something similar to ginkgo where it improves blood flow. A lot more people have tried ginkgo, and that only seems to help a small portion of people with tinnitus.
       
    22. Tweaker
      Doubtful

      Tweaker Member Benefactor

      Location:
      UK
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      Noise exposure
      Anyone tried pycnogenol recently? I'm going to give it a try as can't do any harm. Wondering if anyone else has any experience with it. My T is so bad that even a slight improvement would be welcome but I have never found anything to help yet and haven't tried anything for a while.
       
    23. Ecip

      Ecip Member

      Location:
      Edmonton, AB
      Tinnitus Since:
      4.11.2015
      Cause of Tinnitus:
      Still unknown... possibly noise exposure?
      I've tried it. It's expensive and I'm not sure if it did anything. I'd be willing to try it again some time though.
       
    24. Tweaker
      Doubtful

      Tweaker Member Benefactor

      Location:
      UK
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      Noise exposure
      5 days of 160mg and t is still terrible. Also have pressure feeling in ears. Maybe increased blood flow to ears is making me feel this pressure. Weird. Could pycnogenol do this?
       

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