Pycnogenol May Relieve Some Types of Tinnitus

Discussion in 'Alternative Treatments and Research' started by erik, Jul 11, 2012.

    1. erik
      Cool

      erik Member Benefactor Hall of Fame

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012 or earlier?
      Cause of Tinnitus:
      Most likely hearing loss
      https://www.amazon.com/gp/product/B014Q1M4FM/

      Pycnogenol, an antioxidant plant extract derived from the bark of the French maritime pine tree, was effective in relieving tinnitus symptoms by improving blood flow in the inner ear in a recent study published in Panminerva Medica.

      In a study conducted by the Chieti-Pescara University in Italy, 82 patients between the ages of 35 and 55 with mild-to-moderate tinnitus in only one ear, while the other remains unaffected, were studied throughout a four-week period. Tinnitus in all subjects was a result of restricted blood supply to the inner ear, as measured by high resolution ultrasonography imaging of their cochlear blood flow.

      Patients were assigned to one of three groups: A, B and control. Group A consisted of 24 patients who were administered 150 mg/day of Pycnogenol®, group B consisted of 34 patients who were administered 100 mg/day of Pycnogenol®, and the control group consisted of 24 patients who received no Pycnogenol®. None of the patients had previously used medication for their tinnitus symptoms.

      At the beginning of the study, patients’ average initial systolic and diastolic blood flow velocities were 14.3 and 4.22 cm/sec in the low-dose Pycnogenol® group and 13.2 and 3.2 cm/sec in the high-dose Pycnogenol® group, indicative of insufficient blood perfusion of the ear in both groups. The study found after four weeks of treatment with Pycnogenol®, inner ear systolic and diastolic blood flow velocities in the affected ear rose to an average of 21.2 and 8.23 cm/sec in the low dose group and to 24.3 and 12.5 cm/sec in the high dose group. Not only are these results significant for the improvement of inner ear blood micro-circulation and, consequently reduction of tinnitus symptoms, but they also indicate the potentially dose-related effect of Pycnogenol® on the condition.

      The study also examined in detail the effects of Pycnogenol® on the symptoms of tinnitus. Using a Subjective Tinnitus Scale (STS) at the inception of the study, subjects were instructed to rate their symptoms from “zero" (low intensity of symptoms) to 15 (constant and severe symptoms). The initial STS average value was approximately 8.8 among patients in the Pycnogenol® group and 7.9 in the control group. After four weeks, STS scores reduced to 5.2 in the low-dose group and 3.3 in the high-dose group, demonstrating a reduction of the disturbing background noise in the effected ear. There were no significant changes within the control group.

      “The study clearly indicates Pycnogenol®’s ability to improve vascular function and restore cochlear blood perfusion, which in turn relieves the severity of tinnitus symptoms" said Gianni Belcaro, a lead researcher on the study along with his team from Irvine3 Vascular labs, Chieti-Pescara University. “The results provide further evidence of the supplement’s natural efficacy for a variety of vascular health symptoms."

      More than 50 million Americans will experience some degree of tinnitus in their lifetime, according to the American Tinnitus Association. Tinnitus is a hearing condition that causes the constant misperception of sound, including hissing, ringing and rushing noises.

      “Impaired blood flow to the ear is a common cause for tinnitus, a disturbing and very debilitating condition that can considerably impact overall health and quality of life," Belcaro said. “With few options available for treatment, this study gave us the opportunity to explore a natural solution to tinnitus symptoms and its causes."

      Pycnogenol® is distributed in North America by Natural Health Science Inc. (NHS).
       
      • Informative Informative x 3
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    2. calin
      Inspired

      calin Member Benefactor

      Tinnitus Since:
      Oct 2011
      Hmmm... nice find @erik!
       
    3. AUTHOR
      AUTHOR
      erik
      Cool

      erik Member Benefactor Hall of Fame

      Location:
      Washington State, USA
      Tinnitus Since:
      04/15/2012 or earlier?
      Cause of Tinnitus:
      Most likely hearing loss
      Hi Calin, it is interesting. I would like to at least try it but I need to find out if I am allergic to the pine bark it is made from. I am allergic to Juniper/cedar trees and not sure if that would also make me allergic to pine trees and pine bark. I hope not.
       
    4. DebInAustralia
      No Mood

      DebInAustralia Member Benefactor Hall of Fame Advocate

      Location:
      Geelong, Victoria
      Tinnitus Since:
      12/2013
      hey guys,

      I wanted to know if anyone actually tried taking this supplement??
       
      • Good Question Good Question x 1
    5. attheedgeofscience
      No Mood

      attheedgeofscience Member Podcast Patron Mighty Benefactor Hall of Fame

      Location:
      Denmark
      Tinnitus Since:
      Resolved since 2016
      Cause of Tinnitus:
      Unknown (medication, head injury)
      Sure. I have used it for years - as an antioxidant, and to help my eczema. Pycnogenol is one of the most potent antioxidants available. However, since my various therapies, I no longer have eczema. And as it happens, I stopped taking Pycnogenol shortly after developing tinnitus - for other reasons. I still have piles of it at home (from PharmaNord). I can give it another go, if you want. But, it is unlikely to be of help in chronic tinnitus. I can see how it might be of help in people with vascular diseases/conditions - and perhaps preventing tinnitus from occuring in the first place. Instead, I will be discussing vitamin B12 injections in the week ahead with the doctors overseeing my treatment plan.
       
      • Informative Informative x 1
    6. MattK

      MattK Member

      Tinnitus Since:
      2/13/2014
      Thanks for all that info, Erik. I fully believe that every possible lead is worth looking into. Taking Pycnogenol, if for no other reason, would be beneficial as it is a potent antioxidant.

      I'm glad that there are some positive reports about supplementation, as I think supplements often get a bad wrap. I think part of the problem is that people are naturally more skeptical to supplements than they are to conventional medicine. And in my opinion, a better case can be presented for natural methods (diet, exercise, nutrition, and supplements) than they can be made for conventional medicines in a lot of areas of health. And when supplements do appear to work, they often aren't given credit, and usually the person says, "I don't know for sure, but I think x supplement helped my condition"... I understand the skepticism, but then again, if I take Tylenol for a headache, and if that headache goes away, I can't necessarily prove that the Tylenol got rid of the headache rather than it is just coincidental. Furthermore, there have been times when I've had a headache when it seemed like doubling the dose of Tylenol didn't do squat... but I didn't suddenly come to the conclusion that Tylenol is no different than a placebo.

      Also, I have found that sometimes there are simply poor studies done with supplements. The most common one I see is with vitamin E. The big scare study I saw with vitamin E being linked to cancer was using dl-alpha tocopherol, which is a synthetic form of vitamin E, and even the most hardcore naturopathic researchers have said for years that there are problems with the synthetic vitamin E. Naturally, vitamin E exists in 8 different forms (4 tocopherols and 4 tocotrienols), the most common in food being d-alpha tocopherol ("dl" is synthetic and vitamin E only exists as "d" in nature).

      Another point we must remember that when one eats whole foods rich with certain types of vitamins like vitamin E, for example, they aren't just eating vitamin E alone. But naturally, there are supportive antioxidants involved, such as selenium. This stuff works as a "team", i.e. there is a difference between eating an orange with its vitamin C content and its naturally occurring bioflavonoids versus taking a straight vitamin C pill with no supporting bioflavonoids or other antioxidants. In other words, vitamins and minerals do not work independently like medication does. To do so would be like sending a quarter back out by himself to play against the opposing team without his other team members--it's not that the quarter back's position doesn't "work", but his position isn't designed to make up for the rest of his team.

      lol, well, that's my little rant. I realize some will disagree with what I'm saying, but think about this: to say that vitamins don't work, is to say that all foods are equally nutritious. The reason why some foods are considered better than others largely have to do with their vitamin and mineral content. Why would you want to eat carrots which are high in vitamin A (mainly as beta-carotene) versus eating a Twinkie? It makes no sense to say vitamins and minerals have no worth; that's basically saying all foods are created equal and there is no point in choosing healthy options.

      Ok, rant over... this seriously started off as a post more relevant to Pycnogenol, but then I have seen supplements slammed on this site so much, that I just finally had to say something, lol... oh, and just because supplements may not help with tinnitus, also doesn't mean supplements "don't work". That's like saying all the over the counter medication at Wal-Greens don't work because none of them, (acetominophen, ibuprofen, claritin, Afrin, cough drops, etc) work for tinnitus.
       
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    7. tomytl
      Grumpy

      tomytl Member Benefactor

      Tinnitus Since:
      10 Years
      Cause of Tinnitus:
      unknown
      • Good Question Good Question x 1
    8. demiles

      demiles Member

      Tinnitus Since:
      12/1992
      I'm going to give this a try. A recent trial of Cialis had reduced my T a significant amount so this could be a solution for me.
       
    9. BBarbara
      Curious

      BBarbara Member

      Location:
      Lisbon Portugal
      Tinnitus Since:
      3/2015
      Cause of Tinnitus:
      Stress or Acoustic trauma
      Hello! Has anyone tried pycnogenol?
       
      • Good Question Good Question x 1
    10. jimH
      Caffeine

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
      Hi Barbara.....Yes, for years, and up to 100 mg a day. I take it because it is supposed to be a powerful antioxidant. However, it never had any beneficial effect on my tinnitus.
       
    11. Tom Gatwick

      Tom Gatwick Member

      Tinnitus Since:
      09/2008
      Where can this be bought cheapest? So expensive everywhere...
       
    12. jimH
      Caffeine

      jimH Member Benefactor

      Tinnitus Since:
      30 years+
      Cause of Tinnitus:
      Acoustic trauma
      If you're going to give it a try, it's worth noting that in the OP, one group was put on 100mg and the other 150mg per day. The third group received no Pycnogenol. After my first post in this thread I gave it another go by increasing my dosage from 100mg/day to 200mg/day and experienced no change in my tinnitus.

      Yeah... it is indeed expensive. Here are some different brands sold on Amazon. You can do some additional price comparisons there if you haven't already:

      https://www.amazon.com/Pycnogenol-Nutritional-Supplements/b?ie=UTF8&node=3774621
       
    13. buzzer

      buzzer Member

      Tinnitus Since:
      1971
      I take have taken Pycnogenol on and off for the last year and a half. Even though it says it takes a few weeks to have any results the first 3 days I took it my tinnitus almost went a way completely, then came back on the 4th day.

      I took it for about 60 more days but only occasionally did it seem to be milder. I have tried it on and off again since with some results, but nothing like the first 3 days. Sometimes using other varieties of white pine bark supplements.

      I am going to start again with a stronger dose of Pycnogenol.

      The main thing it did was give me hope that my tinnitus is curable since I did experience 3 days of relief for the first time in years.
       
      • Like Like x 1
    14. _Chris

      _Chris Member

      Location:
      Indiana
      Tinnitus Since:
      12/2015
      Cause of Tinnitus:
      medication?
      I have not tried this myself. However, I heard a positive report that I thought you might find interesting to know. I recently began seeing a therapist who has worked with some other tinnitus patients previously, to try to work on developing some better coping skills. He mentioned that two of his patients had independently discovered that they obtained some relief from pine bark extract. One of them apparently felt that their tinnitus went from a '10' to a '4'. It seems that it may take a while for the benefit to kick in, like a month or so.

      I'm afraid I don't know any additional details beyond this. This was just something that came up in conversation when we were going over medicines I take and other similar kinds of general information. It was not a recommendation. I would be interested in knowing if anyone on the forum had any luck with this one. It seems like a pretty benign supplement to try.
       
    15. GregCA
      Jaded

      GregCA Member Benefactor Hall of Fame

      Tinnitus Since:
      03/2016
      Cause of Tinnitus:
      Otosclerosis
      Are you talking about this?
       
      • Optimistic Optimistic x 1
    16. _Chris

      _Chris Member

      Location:
      Indiana
      Tinnitus Since:
      12/2015
      Cause of Tinnitus:
      medication?
      Yes. It seems doubtful that very many people have benefited or I suppose there would be a lot more written about it here. Nevertheless I felt it might be worth contributing what I had heard.

      On reading more about it, it seems as though if it was going to provide any benefit, it would be something similar to ginkgo where it improves blood flow. A lot more people have tried ginkgo, and that only seems to help a small portion of people with tinnitus.
       
    17. Tweaker
      Transparent

      Tweaker Member Benefactor

      Location:
      UK
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      Noise exposure
      Anyone tried pycnogenol recently?

      I'm going to give it a try as can't do any harm. Wondering if anyone else has any experience with it. My tinnitus is so bad that even a slight improvement would be welcome but I have never found anything to help yet and haven't tried anything for a while.
       
      • Good Question Good Question x 1
    18. Ecip

      Ecip Member

      Location:
      Edmonton, AB/Switzerland
      Tinnitus Since:
      4.11.2015
      Cause of Tinnitus:
      Still unknown... possibly noise exposure?
      I've tried it. It's expensive and I'm not sure if it did anything. I'd be willing to try it again some time though.
       
    19. Tweaker
      Transparent

      Tweaker Member Benefactor

      Location:
      UK
      Tinnitus Since:
      05/2010
      Cause of Tinnitus:
      Noise exposure
      5 days of 160mg and tinnitus is still terrible. Also have pressure feeling in ears. Maybe increased blood flow to ears is making me feel this pressure. Weird. Could pycnogenol do this?
       
      • Agree Agree x 1
    20. MattL
      Jaded

      MattL Member

      Location:
      Australia
      Tinnitus Since:
      10/2009
      Cause of Tinnitus:
      Meniere's
      I took pycnogenol for 2 months to help with my Meniere's, but I believe it made my symptoms worse.
       
      • Informative Informative x 1
    21. Pleasure_Paulie

      Pleasure_Paulie Member

      Location:
      Australia
      Tinnitus Since:
      06/2016
      Cause of Tinnitus:
      Noise or maybe... unicorns!
      This does nothing and quite expensive too.
       
      • Informative Informative x 1
    22. JurgenG
      Approved

      JurgenG Member Benefactor

      Location:
      Belgium
      Tinnitus Since:
      12/2016
      Cause of Tinnitus:
      Loud noise exposure / headphone accident maybe?
      Are you sure it's related?
       
      • Good Question Good Question x 1
    23. Jed Fischer

      Jed Fischer Member

      Tinnitus Since:
      1 month.
      Cause of Tinnitus:
      Unknown. Suspected HIT
      • Informative Informative x 2
    24. Seemmkay
      Curious

      Seemmkay Member

      Tinnitus Since:
      11/2015
      Cause of Tinnitus:
      Gunshot
      Hey all.
      Wanted to share some research I came across from PubMed on the use of pine bark extract (under the trade name Pycnogenol) to treat mild to moderate tinnitus. The results looked promising. Besides the myriad anti-inflammatory and other amazing health benefits of this extract, researchers found it increases cochlear blood flow, and helped reduce tinnitus symptoms "in a short period of time." The extract can be purchased in bulk for relatively cheap.

      You can read the study here: https://www.ncbi.nlm.nih.gov/pubmed/20657537

      All the best to you guys.
       
    25. Lulu187

      Lulu187 Member

      Tinnitus Since:
      1 week ago
      Cause of Tinnitus:
      Unknown
    26. InfiniteLoop
      Relaxed

      InfiniteLoop Member Benefactor

      Location:
      Redwood City, California
      Tinnitus Since:
      01/21/2014
      Cause of Tinnitus:
      High frequency hearing loss in left ear from head trauma (?)
      The papers are about Meniere’s and blood flow as main root causes. If you are here because of sensorineural hearing loss (as is the case for the immense majority), the likely outcome will be nothing.
       
    27. Lulu187

      Lulu187 Member

      Tinnitus Since:
      1 week ago
      Cause of Tinnitus:
      Unknown
      I believe I'm here for blood flow because my tinnitus is not noise induced.
       
    28. InfiniteLoop
      Relaxed

      InfiniteLoop Member Benefactor

      Location:
      Redwood City, California
      Tinnitus Since:
      01/21/2014
      Cause of Tinnitus:
      High frequency hearing loss in left ear from head trauma (?)
      How do you know your tinnitus is not hearing loss related? In many cases, it does not matter the root cause that much if there is hearing loss. Get an audiogram to 16 kHz.
       
    29. Lulu187

      Lulu187 Member

      Tinnitus Since:
      1 week ago
      Cause of Tinnitus:
      Unknown
      I had a full hearing test done and I have absolutely no hearing loss
       
    30. InfiniteLoop
      Relaxed

      InfiniteLoop Member Benefactor

      Location:
      Redwood City, California
      Tinnitus Since:
      01/21/2014
      Cause of Tinnitus:
      High frequency hearing loss in left ear from head trauma (?)
      If there is truly no hearing loss then you should get a very exhaustive blood work and health check to troubleshoot any possible problem that might have tinnitus as a symptom. If your diet is very rich in carbohydrates/sugar it might be a good time to review and go to a healthier one.
      Most doctors will have very little interest to troubleshoot the tinnitus root cause, and you will have to be very proactive about the kind of tests you want.
       
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