Hello everyone, It's been awhile since I've posted a thread on here all because I've been trying my absolute best over these 9 continuous months of dealing with my hearing changing, ringing, and the horrible symptoms that have come directly from it. Although this thread is not actually for support, I wanted to ask this question that has been popping up every now and then in my head. This is because of how many times antidepressants have been told to be the solution to my problem(s). It's really given out like it's candy. I've done everything I can once again, over these 9 months, to not have to take any sort of medication involving significant structural or chemical changes to my brain. Most importantly, any medication that would or could leave me with certain brain damage or irreversible changes to my brain. Therefore, I have strictly stuck to using supplements, herbs, dieting, spices, and other healthy options to push through these days. Although, I'm starting to struggle more and more to just get through a day. The term "Anhedonia" is at the top of the list of the issues I'm dealing with now. Finally though, the question I wanted to ask is: Why do most antidepressant medications have to change brain circuity? I'm sure everyone knows that antidepressants affect certain neurotransmitters in our brain like Serotonin or Dopamine. I understand that the thalamus has an important task with our sensory system, but my biggest misunderstanding is why is such significant circuitry changes needed? Is it to bypass unknown damage that has taken place in the brain?