Riluzole May Have Got Rid of My Benzo Induced Tinnitus. Also Residual Inhibition Question.

Discussion in 'Support' started by JasonP, Jul 8, 2018.

    1. JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      Okay, I actually have multiple types of tinnitus so I don't know how this will work for everyone but I have had some kind of a static like tinnitus from benzos and if I remember right, if I would use residual inhibition the static would go away for a some seconds or so. Well, I had managed to lay off the benzos and take some other stuff and after a month or two of being off the klonopin, most of the static went away or at least that I could hear..maybe some other sounds were covering up the rest of the static. Well, something came up a couple of days ago and I took klonopin again and I guess that is how it came back...maybe it was something else in addition I took (gabapentin, meclizine, or cyproheptadine) it sounded the same as the benzo tinnitus. Well, I took a drug called Riluzole (I took 50mg) early this morning and the static went away in 30 minutes to an hour I think, then I took some Gabapentin and went back to sleep and it came back after I woke up. In general the other types of tinnitus were low so I put up with the static today but it's not my favorite sound. Tonight it started bothering me in a quiet room so I decided to take Riluzole again. That was the ONLY med I took and within 30 minutes to an hour or so it went away. Riluzole a drug that works on glutamate.

      There is a whole thread on Riluzole here if you are interested in learning about it:

      https://www.tinnitustalk.com/thread...iluzole-ignorant-stupid-or-worth-a-try.17437/

      Here is my other question though, it basically sounds now very similar to what it would sound like when I did residual inhibition a long time ago (some of my tinnitus is still there but the stuff that disappeared with residual inhibition is mostly all gone or at least close to all gone). I wonder if this would work on other people's tinnitus who are able to get relief from residual inhibition? Maybe not all of them but I wonder about some.

      Granted this could be temporary. After some time I think the benzo type static will disappear on it's on without the Riluzole though. One other thing, I have also been taking a drug called Lamictal for a couple of years now so that could have some kind of synergistic affect with Riluzole, I don't know. Since I have other tinnitus sounds I can't be sure all the static is gone but I can definitely say that most of it has. This is not a placebo effect.

      The only side effect I noticed was that I got a little sleepy for like an hour after it kicked in. It also seemed to have anti-OCD effect but that could have been do to my emotions changing a little when the drug kicked in or the fact that the static T went away.
       
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    2. Michellejean

      Michellejean Member

      Location:
      Maine
      Tinnitus Since:
      03/1/18
      Cause of Tinnitus:
      Virus/ no clue
      Hi can you tell me about residual inhibition?
       
    3. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      Sure, residual inhibition is when an external masking noise of a certain volume and frequency that is able to briefly quiet your tinnitus once the sound goes away. You have to be careful with it because you don't want it to be too loud where it hurts your ears.

      Here is a website that explains more about it:
      https://www.audiologyonline.com/ask-the-experts/what-neurological-basis-for-temporary-11618

      I remember going to hushtinnitus.com and trying it years ago. It's only temporary for a very short period of time so a it's not a cure.
       
    4. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      I need to make a correction. In the top of the thread I said I took 50mg Riluzole. Well, that was wrong. I actually took 100mg Riluzole on accident. I thought each tablet was 25mg for some reason. Not sure what the heck I was thinking. I think the normal prescribing dose is 50mg twice a day.
       
    5. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      It's been over a year and I mostly forgot about this post. I actually had a fire alarm go off yesterday and some of this "staticy" type tinnitus sound came back for me. I wondered if Riluzole would take it away but since I have been habituating to it so much better and am somewhat scared of medications right now, I didn't want to take it. It got me wondering if Riluzole may help with certain kinds of noise induced tinnitus that are static like for other people though. It doesn't seem to work on my tinnitus that was caused by anti-depressants although I only took it for one day at a time.

      Has anyone else tried this medication that had noise induced tinnitus or benzo induced tinnitus? I'm just curious.

      By the way, I'm not trying to promote this drug and I have no idea how safe it is. After benzo withdrawal, anti-depressants causing tinnitus, and side effects of other drugs, I am kind of scared of drugs right now, however, I may try it again if it gets bothersome.
       
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    6. Bobby Sinatra

      Bobby Sinatra Member

      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Ambien Windrawal Suspected
      Did you have a chance to use Riluzole again?
       
    7. Chinmoku

      Chinmoku Member Benefactor

      Tinnitus Since:
      10/2018
      Cause of Tinnitus:
      Unknown, possibly medication
      @JasonP , to sum up this long thread, you took riluzole 100mg and your benzo induced static went away?
      Did it stay away or did you have to take the riluzole continually? I have very loud static due to pregabalin and wonder if I could take riluzole to reduce it. I don't think I can find a doctor prescribing it in the UK, GPs refuse to prescribe anything that is not recommended by a specialist, and specialists here do not know that drug.
       
    8. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      Well, instead of using the drug, I put on my maskers some of the time. It seems like it went down over a period of days.

      From what I remember the tinnitus stayed away as long as I didn't go back to sleep after taking it. Granted, I only took it a few times. Sleep and/or klonopin and sleep sometimes would bring the static back.
       
    9. all to gain
      No Mood

      all to gain Member Podcast Patron Benefactor

      Tinnitus Since:
      -
      Cause of Tinnitus:
      -
      This is me all over. I hate drugs. Never want to see one again, except I must as my body can't now cope without them. I think they have completely messed with my nervous system.

      However, the only hope for a cure may come in the form of a drug.
       
    10. Bill Arsenault

      Bill Arsenault Member

      Location:
      Boston.
      Tinnitus Since:
      Permanent and intrusive since 2017.
      Cause of Tinnitus:
      Medication / Noise Over Exposure
      I can’t say for certain what initiated my tinnitus because I have played electric guitar for 35 years as well as some intense work environments, hundreds of rock concerts,
      many fistfights, and a few untreated concussions and neck injuries.

      I also have abused or tried just about every drug - pharmaceutical or otherwise.

      I do know for a fact that in my case once the tinnitus began and my ears were comprised due to it -regardless of which straw broke the camels back- I have yet to find a single
      pharmaceutical that does not increase my tinnitus significantly and permanently even in the smallest doses.
      Even noise exposure does not have that severe of an effect on my tinnitus as drugs do.
      The hell of it is that I had tinnitus for over a year before even hearing the word Otoxicity.
      And by that time I was on everything trying to combat the fear, anxiety and depression.

      Then I spent another year learning about Ototoxicity and weaning off each drug one at a time in order to find the culprit only to realize in the end that every one of them was doing damage and together they created a toxic soup that has left me with extremely severe permanent tinnitus that leaves me muttering to myself all day and night long
      “I can’t do this, it’s too fucking loud, what am I going to do, this is brutal, I can’t fucking handle it”.

      Man, good luck working, sleeping, or focusing on anything with those words going through you mind non-stop.

      Anyway- what really haunts me is that I seen an ENT 3 months after it began and he didn’t tell me to get off the drugs as soon as possible or even warn me about Ototoxicity.

      And in hindsight I know he knew it was Ototoxicity because he was asking all kinds of questions- but then after I told him about all the drugs I had took and was taking- he just gave me that look and then there were no more questions and he told me to learn to live with it.
      If I could have arrested the progression 2 years ago I would probably still have a life.

      I couldn’t even hear it outside back then and sleeping with a fan on was all that was needed.
       
    11. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      Question: Has anyone on here taken this long term? I'm just curious of the long term effects.
       
    12. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      That's a great question. I can't say for sure either way. Did you ever try it?

      I did find another way to trigger static tinnitus for me and I am wondering if the Riluzole could get rid of it. If I remember correctly, one night not too long ago I took, either .75 mg or 1.5 mg melatonin along with 20mg of Propranolol. I remember the feeling of gas moving from my stomach to my intestines, then two hours later I took .75mg or 1.5mg of melatonin and remember a feeling of gas moving down my intestines after that. I'm wondering if it was activating my parasympathetic nervous system... I'm not sure but I just read in a journal entry I had wrote that I had a weird "feeling in my intestines" when I combined .25mg Klonopin and some melatonin together after not being used to it. In both these instances I woke up with static tinnitus the next day. [Interestingly, the next few days I took 300mcg 6 hour time released with 10mg or 20mg Propranolol and got no static tinnitus upon waking but I didn't feel that intestinal feeling either.] Unfortunately, I only have one Riluzole pill left so I didn't take it but I believe the static was there pretty much the whole day but it was gone the next day. I'm thinking about asking a neurologist about this drug and was wondering if it could be taken on an as needed basis.
       
    13. AUTHOR
      AUTHOR
      JasonP
      No Mood

      JasonP Member

      Tinnitus Since:
      6/2006
      Okay, I'd like to give another update here on Riluzole. I hadn't had the static tinnitus in a long time. A few days ago I woke up one morning and decided to try Riluzole out. I did not have that static type tinnitus.

      Anyways, I took 25mg of Riluzole, it was calming to me, lowered my heart rate maybe within 15 minutes but made no change in my tinnitus.

      Anyways, the past couple of days I have awakened with static tinnitus and thought that was really weird. Upon doing some research it looks like Riluzole can also work on the GABA receptors so what may be the deal in my case is that sleep plus activation of my GABA receptors gives me static tinnitus. This would also explain a while back why Riluzole lowered my tinnitus until I went back to sleep and then woke up with the static tinnitus again.

      Riluzole may not be the answer I was looking for. As it may lower it during the day for me but cause the static the next morning when I wake up. Perhaps low dose Lamictal may be better for me for static type tinnitus.
       

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