JPGL's Recent Activity

  1. JPGL rated BB23's post Informative in the thread Noise-Induced Hearing Loss Alters KCC2 and GABA Inhibition in the Auditory Centers.

    I heard they tried it in the past without success, but then I stumbled into this paper. They seemed to achieve it with gene editing tech, CRISPR....

    Apr 26, 2024 at 7:36 PM

  2. JPGL rated Josh59's post Good Question in the thread Noise-Induced Hearing Loss Alters KCC2 and GABA Inhibition in the Auditory Centers.

    What are the reasons for this? Is it challenging to work on?

    Apr 26, 2024 at 7:30 PM

  3. JPGL rated gameover's post Informative in the thread Noise-Induced Hearing Loss Alters KCC2 and GABA Inhibition in the Auditory Centers.

    I guess so. I did not want to suggest that Resveratrol would be an effective therapy, but it should not hurt. I've been doing more digging for...

    Apr 26, 2024 at 7:29 PM

  4. JPGL rated Jammer's post Informative in the thread Noise-Induced Hearing Loss Alters KCC2 and GABA Inhibition in the Auditory Centers.

    Resveratrol is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is...

    Apr 24, 2024 at 4:01 PM

  5. JPGL liked BadNeighbors's post in the thread Auditory Mirror Therapy for Treatment of Tinnitus.

    I don't think it is going to be grifter copy-cats that do anything to improve our situation, but if Dr. Shore's device can actually alleviate our...

    Apr 24, 2024 at 2:17 AM

  6. JPGL rated BB23's post Useful in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    Great. Visual Snow Syndrome is also a functional connectivity issue. fMRI imaging suggested it was due to dysfunctional serotonin and glutamate...

    Apr 24, 2024 at 1:30 AM

  7. JPGL rated ZFire's post Agree in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I’ve been saying this too. If we want to see rapid and meaningful progress, it starts with every tinnitus researcher recognizing the major...

    Apr 24, 2024 at 1:29 AM

  8. JPGL rated AfroSnowman's post Helpful in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I’d second this message from the tinnitus community. Obviously, any method of measurement has shortcomings, but it would seem like a good best...

    Apr 24, 2024 at 1:28 AM

  9. JPGL rated WilRic's post Agree in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    Obviously, I was kidding, but I entirely agree. The community should let the TRI know that we (or at least a sizeable portion of tinnitus...

    Apr 24, 2024 at 1:24 AM

  10. JPGL rated UKBloke's post Helpful in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    @Hazel, you might already have included the following observations/questions in your presentation, but if not, it'd be great if you were able to...

    Apr 24, 2024 at 1:23 AM

  11. JPGL rated gameover's post Informative in the thread Noise-Induced Hearing Loss Alters KCC2 and GABA Inhibition in the Auditory Centers.

    I have not seen this new paper by Arnaud Noreña and others linked or discussed here yet (forgive if it is linked somewhere). It suggests the real...

    Apr 23, 2024 at 3:38 PM

  12. JPGL rated Nick47's post Helpful in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I'm not for booing, jeering, or animosity of that kind. I am for people from the community expressing their disapproval of Pawel Jastreboff's...

    Apr 21, 2024 at 6:33 PM

  13. JPGL rated BB23's post Good Question in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    Yes. Anyone working on anything to fix the synapses? Is the answer a "no"?

    Apr 21, 2024 at 6:32 PM

  14. JPGL rated UKBloke's post Agree in the thread A Proposed Method of Action for Tinnitus.

    Thanks mate. We press on.

    Apr 21, 2024 at 9:31 AM

  15. JPGL rated Nick47's post Agree in the thread A Proposed Method of Action for Tinnitus.

    However, you were proactive and temporarily brought it to their attention. It was not a waste. Well done!

    Apr 21, 2024 at 9:30 AM

  16. JPGL rated UKBloke's post Hug in the thread A Proposed Method of Action for Tinnitus.

    I've now completed a round of emails to researchers specializing in bio-electronics with interest in the field of tinnitus and those in their...

    Apr 21, 2024 at 9:30 AM

  17. JPGL liked WilRic's post in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    There is a symposium on 12 June, "Tinnitus and Physical Links." Of particular interest would be Robin Guillard's discussion of his study...

    Apr 21, 2024 at 9:28 AM

  18. JPGL liked Joeseph Stope's post in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    Welcome, dear cellmate. I can see that you come from the land of Shakespeare, and you expressed it so aptly. But to the nuts and bolts of this...

    Apr 21, 2024 at 9:25 AM

  19. JPGL rated Joeseph Stope's post Informative in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    First Sounds of the Cavalry Coming? Well, curb your enthusiasm. We've all had our hopes raised and dashed oh so often in the past....

    Apr 21, 2024 at 9:22 AM

  20. JPGL rated dipp's post Agree in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I´ve made a small donation since I don´t know how much longer I will be able to keep working :) By the way, it´s a shame that Pawel Jastreboff is...

    Apr 21, 2024 at 9:19 AM

  21. JPGL rated Cmspgran's post Agree in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I couldn’t agree more it’s time to look beyond that paradigm now, and rightly so; Pawel Jastreboff had had his day. I lost complete respect for...

    Apr 21, 2024 at 9:19 AM

  22. JPGL rated gameover's post Winner in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    Pawel Jastreboff should be a pariah, not a keynote speaker. But when you think about all the useless (at best) therapies his disciples sold and...

    Apr 21, 2024 at 9:16 AM

  23. JPGL liked Muggumbo's post in the thread Tinnitus Research Initiative (TRI) 2024 Conference.

    I'm hoping 2025 will be the year of bimodal stimulation. If Dr. Shore's device succeeds, then I expect to see a lot more research centered around...

    Apr 21, 2024 at 9:15 AM

  24. JPGL rated gameover's post Helpful in the thread Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration.

    Superior hearing would be like higher frequency range... it could create issues with some stuff. I'd gladly take this over tinnitus and fragile...

    Apr 20, 2024 at 8:23 PM

  25. JPGL rated Muggumbo's post Agree in the thread Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration.

    I'd take it even if it was a suppository!

    Apr 20, 2024 at 8:12 PM

  26. JPGL liked Fields's post in the thread Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration.

    I personally thought this was a little funny: Imagine going from hearing loss and tinnitus on one end of the scale to not being able to sleep...

    unlimited-power-star-wars.gif Apr 20, 2024 at 8:11 PM

  27. JPGL rated gameover's post Winner in the thread Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration.

    Imagine we could take a pill and repair these nerves!

    Apr 20, 2024 at 8:10 PM

  28. JPGL liked Fields's post in the thread Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration.

    Excerpt from a recent article on the New Scientist:

    Apr 20, 2024 at 7:40 PM

  29. JPGL rated ploughna's post Good Question in the thread Repeated Bilateral Transcranial Direct Current Stimulation over Auditory Cortex for Tinnitus.

    There's an active thread already on here for rTMS, tACS, tDCS, etc., that's been going since 2012, quoting various studies, people's experiences,...

    Apr 20, 2024 at 7:13 PM
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