tommyd87's Recent Activity

  1. tommyd87 rated Jurger's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Perhaps ototoxicity and patients with severe and profound hearing loss, regardless of the cause of the hearing loss. Lucchino once stated he hoped...

    Aug 15, 2020 at 7:55 PM
  2. tommyd87 rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    They will. It makes perfect business sense to do what they are doing. Right now they have a drug that shows evidence of restoring at high...

    Aug 15, 2020 at 7:12 PM
  3. tommyd87 rated Jaysterk's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    You won't. Even if FX-322 fails. This technology IS the future and more than likely a cure. Being able to regrow hair cells is way beyond our...

    Aug 15, 2020 at 7:07 PM
  4. tommyd87 liked WillBeNimble's post in the thread Hough Ear Institute's Hair Cell Regeneration Project.

    But it hasn't in human models, as far as I know. They have some evidence it could help from animal models, but they don't know. As for what...

    Aug 15, 2020 at 5:32 PM
  5. tommyd87 replied to the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    Yeah I can see that this then won’t be a project that he will lie down on. Wouldn’t surprise me if he doesn’t either try and force the issue or...

    Aug 15, 2020 at 5:26 PM
  6. tommyd87 rated FGG's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Something to consider along with this is that even if Frequency had been funded by Jeff Bezos, they couldn't have developed FX-322 until Jeff Karp...

    Aug 15, 2020 at 4:49 AM
  7. tommyd87 liked Thuan's post in the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    I believe they are treating hearing loss, or rather as FGG puts it as hearing interference, resulting from Meniere's except this hearing loss...

    Aug 15, 2020 at 2:09 AM
  8. tommyd87 replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    That now makes much more sense, thanks. That means their SPI-5557 treatment is the regrowth one then.

    Aug 15, 2020 at 2:09 AM
  9. tommyd87 rated kelpiemsp's post Winner in the thread University of Minnesota Tinnitus Research with Acoustic and Body Stimulation.

    Well I was in trial and had tinnitus for 30 years. The general eligibility requirements are there for study design purposes mainly. You start with...

    Aug 15, 2020 at 1:34 AM
  10. tommyd87 rated Rubenslash's post Helpful in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Might be but I would travel to any place in the world if it could give me some relieve and improved hearing.

    Aug 15, 2020 at 1:21 AM
  11. tommyd87 replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    OK so when Sound Pharmaceuticals states that they are treating hearing loss with this treatment, they are actually referring to associated...

    Aug 15, 2020 at 12:48 AM
  12. tommyd87 replied to the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    I can’t see it taking ten years. I reckon Musk might put in money to try and speed this up.

    Aug 14, 2020 at 8:33 PM
  13. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Frequency will have to instigate this themselves. This tends to be the time where the mainstays might attempt to cause disruption. I do think...

    Aug 14, 2020 at 8:25 PM
  14. tommyd87 rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It's good to see Frequency is presenting how FX-322 will benefit ENT and Audiologist practices in the future. When FX-322 is commercialized, there...

    Y4T7bqA.png Aug 14, 2020 at 8:23 PM
  15. tommyd87 replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    Ahh so it doesn’t assist regrowing stuff but it helps hearing. How does it intend to work with that then? Sorry science isn’t my strong point.

    Aug 14, 2020 at 8:02 PM
  16. tommyd87 replied to the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    Musk does best when he has science supporting his claims and also when he has an option which can disrupt the mainstream market. I predict that...

    Aug 14, 2020 at 7:29 PM
  17. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    When it comes to hearing, you either hear or you don’t. The previous discussion was related to testing hearing, however there is no way Frequency...

    Aug 14, 2020 at 7:24 AM
  18. tommyd87 replied to the thread Sound Pharmaceuticals (SPI-5557 & SPI-1005).

    Is there a reason that you can point me towards as to why SPI-1005 doesn’t fall under hearing regeneration? Right now I know that they are...

    Aug 14, 2020 at 7:13 AM
  19. tommyd87 liked Lucifer's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I also don’t think it’s a scam, or how did those patients have improved word scores after they got the FX-322 injection. The likelihood of the...

    Aug 14, 2020 at 12:57 AM
  20. tommyd87 replied to the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    To me this has actually got the submarine rescue written all over it again. Musk makes a claim contending that he can come up with an advanced...

    Aug 13, 2020 at 11:40 PM
  21. tommyd87 rated egowisp's post Helpful in the thread Elon Musk’s Neuralink Looking to Treat Tinnitus.

    Just want to say that this man could definitely fund any number of non-invasive projects for tinnitus (pills, shots, etc.) but he wants to instead...

    Aug 13, 2020 at 11:35 PM
  22. tommyd87 rated Pre55ure's post Agree in the thread Aldosterone and Hearing.

    I'm all for trying anything that might help (assuming it doesn't have more than minor adverse effects) but the underlying causes of high frequency...

    Aug 13, 2020 at 11:34 PM
  23. tommyd87 liked serendipity1996's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Yeah, I get you although I think it's useful to distinguish between failures and 'scams.' Failure is an inevitable risk when developing new drugs...

    Aug 13, 2020 at 11:15 PM
  24. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    The interesting information from that graph is that two people both had the same score increase in word recognition, however only one of them was...

    Aug 13, 2020 at 9:31 PM
  25. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I think that a fair part of it comes down to the desire and need to show that the treatment has benefit or can show benefits during the trial....

    Aug 13, 2020 at 8:13 PM
  26. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Have you been given a reason why you we’re not wanted as a trial participant? It indicates to me that you must have actually been rejected because...

    Aug 13, 2020 at 10:59 AM
  27. tommyd87 replied to the thread Frequency Therapeutics — Hearing Loss Regeneration.

    There definitely were two dose categories, a low dose and a high dose, in the initial Phase 1/2 trial. I thought that there were six people who...

    Aug 13, 2020 at 2:39 AM
  28. tommyd87 replied to the thread Pipeline Therapeutics.

    Savvy specialists will take records of what treatment(s) worked with what patients, based off their condition(s). This way they will at least...

    Aug 13, 2020 at 2:28 AM
  29. tommyd87 replied to the thread Pipeline Therapeutics.

    Unknown, although an eligibility criteria for OTO-413 clinical trial is that you have normal hearing and/or mild hearing loss. Thus it seems...

    Aug 13, 2020 at 2:02 AM
  30. tommyd87 liked Diesel's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I'm not so sure about this. They're yet to reveal what exactly is planned to "understand other populations that FX-322 may help treat" from the...

    Aug 12, 2020 at 9:46 PM
  31. tommyd87 liked patorjk's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    The language they use is kind of strange (ex: "the hearing benefit"). 1 of the 4 responders had a word score that dropped from being statistically...

    Aug 12, 2020 at 9:33 PM
  32. tommyd87 rated Diesel's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    I hate delays. But, I'd rather they take the time to get as much data as possible from the participants Phase 2A. The breakthrough designation...

    Aug 12, 2020 at 3:17 PM
  33. tommyd87 rated UKBloke's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    It's nice that they mention tinnitus in that report.

    Aug 12, 2020 at 3:17 PM
  34. tommyd87 rated WillBeNimble's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Q2 2021. Sad face. Stupid pandemic, slowing vital hearing loss drugs.

    Aug 12, 2020 at 3:17 PM
  35. tommyd87 rated Kain's post Genius in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Frequency Therapeutics has shared its Q2 2020 financial results and recent business updates....

    Aug 12, 2020 at 3:17 PM
  36. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    I agree, however most patients (especially those outside America) actually aren’t eligible to get the treatment through the insurance anyway. Thus...

    Aug 12, 2020 at 3:14 PM
  37. tommyd87 replied to the thread Aldosterone and Hearing.

    If it is successful, how long do you presume it will take to work?

    Aug 12, 2020 at 10:52 AM
  38. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    According to Hough Ear Institute, the only benefit from conducting the PoC (Proof of Concept) study is to receive coverage from insurance if the...

    Aug 12, 2020 at 10:44 AM
  39. tommyd87 rated Rubenslash's post Agree in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Remarkable statement considering that we don't yet know how Otonomy will try to restore hair cells. AFAIK it's pre-clinical and more information...

    Aug 12, 2020 at 4:18 AM
  40. tommyd87 rated WillBeNimble's post Useful in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    True, we don't know how Otonomy is regenerating hair cells. FX-322 is currently the furthest ahead though, and is the best that can be seen with...

    Aug 12, 2020 at 1:11 AM
  41. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    Further follow up from Hough Ear Institute - Much clearer now: This is a lot more clearer compared to the previously provided details. So it...

    Aug 11, 2020 at 11:55 PM
  42. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    Further update from Hough Ear Institute: This answer still simply makes so little sense. On the one hand, we are told that the drug is ready to...

    Aug 11, 2020 at 5:51 PM
  43. tommyd87 liked Reinier's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    At Frequency Therapeutics they think that so called hidden hearing loss is actually hearing loss at the high frequencies that a normal hearing...

    Aug 11, 2020 at 5:22 PM
  44. tommyd87 liked Silvio Sabo's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    If you listen to the Tinnitus Talk Podcast about Frequency Therapeutics with their representative Carl LeBel, he speaks about this. At Frequency...

    Aug 11, 2020 at 5:22 PM
  45. tommyd87 attached a file to the thread Akouos — A New Company Focused on Genetic Hearing Loss.

    There There is a newsletter you can sign up to on their website too which they release each quarter. [ATTACH] The above image is a...

    6C526BAA-2A01-461C-AEE1-B9864EE12178.png Aug 11, 2020 at 7:57 AM
  46. tommyd87 liked Diesel's post in the thread Frequency Therapeutics — Hearing Loss Regeneration.

    Lucchino's and Loose's monthly stock sales are part of a 10b5-1 plan. It's a plan that allows insiders to buy or sell their shares of the firm...

    Aug 11, 2020 at 2:24 AM
  47. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    That’s the type of answer Hough hopefully will give/should have given if accurate from their end. However this should have been done at a much...

    Aug 11, 2020 at 2:23 AM
  48. tommyd87 liked Thuan's post in the thread Hough Ear Institute's Hair Cell Regeneration Project.

    The link below explains that proof of concept vs traditional clinical trials pathway. I found it quite interesting and answers some of the...

    Aug 11, 2020 at 2:19 AM
  49. tommyd87 replied to the thread Hough Ear Institute's Hair Cell Regeneration Project.

    Interesting update regarding the pill. Question: Answer: There was a follow up question asked which was: The above has not been answered at...

    Aug 11, 2020 at 12:38 AM