Recent content by Josh NH USA

It appears that there is currently an open-label phase 3 trial extension taking place. https://clinicaltrials.gov/study/NCT06859788

Which two anticonvulsants were recommended?

I’m right there with you. I’m in my 40s, with young kids. During my first few months of tinnitus, I came quite close to ending my life because of days of continuous insomnia. I’m still struggling three years later with depression, anxiety, insomnia, and guilt, but the pull of suicide has faded a...

Where did you read that Wayne Kent Taylor tried Lenire? Wikipedia reports that he tried an “experimental treatment,” but the footnoted link is an article behind a paywall. https://en.wikipedia.org/wiki/Wayne_Kent_Taylor

@UKBloke, for context, that is one of the figures accompanying Dr. Shore’s journal article published after the most recent human study. It is easy to find online; it is eFigure 5 in the supplement to the article. I have attached a PDF of the full text of her article, along with the supplement...

My candid reaction: I watched the informative Q&A and felt reassured that some hope is still alive and well. Then I sighed and prepared myself for at least sixteen more months, though probably years. The suffering continues, but the darker thoughts are postponed.

If by LLM you mean large language models, then I find it hard to put too much trust in what they say. A few days ago, I asked one a question related to my profession and received a definitive answer. I then copied and pasted that same answer back into the same LLM to check it, and it told me the...

I’ve wondered about this rather vague concept as well. I also recall that Dr. Shore’s earlier studies focused on noise-induced tinnitus in animals, such as guinea pigs and possibly mice, in relation to the DCN. However, I’m not sure that noise-induced necessarily means somatic in any strict...

Is anyone else as nervous as I am for October 13, 2025? I feel like my life is at stake. I've survived three years of constant ringing in my right ear, and finding hope has been a real challenge. The Q&A on October 13 is going to hit me hard either way. This thread and community have kept me...

Reversing Synchronized Brain Circuits With Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts

For what it is worth, Dr. Shore’s prior paper was published in March 2018, whereas I believe the preceding study results came in May 2017. See below links. Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans...