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[ATTACH] Just look at these beautiful little machines :)
Study finds that sound plus electrical body stimulation has potential to treat chronic pain Interesting. More benefits from bimodal stimulation....
Could also be for the fact that there are not enough devices available, and only one location for all assessments. 2-3 visits a person for 400...
Could be indeed, but i thought the main table showed 400 participants too. This is the change log:...
I thought I was crazy. But I checked the change log. It says the number of participants didn't change...! I'm sure it said 400 in the planning.
We can speculate if we want because... Study completed! There are some people walking around on Mother Earth that perhaps now have the knowledge...
I think you have to realize that there will be no one-pill-fix for this problem and that sound therapy to reconfigure the brain shows benefit...
University of Auckland scientists are excited by results from a trial of a new treatment for tinnitus.After 20 years searching for a cure for...
Unfortunately it is not EMA approved yet, so not available in the EU. Would love to try though as the research is very encouraging.
That's great to hear. Are you following the study protocol or your doctor's normal protocol? Could you confirm that you are using the high dose...
If you are still up for trying a nasal spray, I'd try XHANCE from Optinose. Early trials show 80% of people with ETD improve. Use the search...
They actually started recruiting as per yesterday and postponed the finishing date by three years. :/ See updated page.
For those that have missed this .PDF containing some of the steps on software development and market launch:...
Glad to help. I'd love to try it for my ear fullness and ETD problems but it is not EMA approved as usual. Not available in EU. Do let us know if...
Sorry for kicking up this thread without any real update, but you are late Dr. Shore! July is long behind us :)
If you are based in the US, you might give Optinose's XHANCE nose spray a chance. It is currently trialed for ETD but already approved for other...
Abstract High-intensity sound or blast-induced hearing impairment is a common injury for Service members. Epidemiology studies revealed that the...
Study Drug (XEN1101) There is a dedicated website launched for the MDD trial for those who are interested. 66% chance of getting the real drug,...
Travis, call the hospital where this trial is ongoing. Ask for the one overseeing the trial at the moment. https://clinicaltrials.med.nyu.edu/...
New studies are starting/completing daily on ClinicalTrials.gov. I don't post everything but in the last weeks some new studies closed recruiting...
OTO-313 was definitely not on my list to look out for - I'd stay away from injections trough the eardrum personally. Do not give up hope, Dr....
Yes, correct.
Definitely not always. My tinnitus reacts to everything and will even spike from a 5 minute walk outside without any cars nearby. With really...
For laser, yes, use both. For normal drill, I'd say drill without earmuffs. Suction in between with earmuffs. Annoying to put on and off though....
Same here. The electric hand drill is really not loud. The suction tube is the problem for me. I posted my experience with the laser for cavities...
Phase 3 started! :) Sound Pharma initiates enrollment in pivotal Phase 3 clinical trial of SPI-1005 for the treatment of hearing loss and...
The drill is indeed not that loud. The suction tube is imo. You didn't feel that way?
After a permanent worsening of my tinnitus after having a small cavity drilled in December, I looked for a laser dentist. I have interproximal...
DBS is highly invasive and a last resort solution. It is not uncommon for a healthcare provider to accept you only if all current treatments have...
The Study of Wuling Capsule in Treatment Chronic Tinnitus Trial completed as per yesterday. I don't expect much - 4 year trial of 59 patients...
I kindly disagree with 1), 2) and 3). We do not know for who the treatment works yet. As for the scope of the trial, you want to make sure your...
Hi Tom, welkom :) Wish you the best with your travels. Please keep in mind that there are actual treatments in the pipeline which are either...
There are so many unidentified subforms of tinnitus that your ENT most likely has no idea. I have had three permanent worsenings during my first...
I have gotten permanent spikes from low frequency noises (air-conditioning, fans etc) well below 50 dB. You are definitely not alone in this. We...
Believe me, sometimes it's a blessing to be alone, without kids or your spouse inviting family and friends over etc. The first 1-3 months they...
Effects of Tumor Necrosis Factor Blocker on Salicylate-Induced Tinnitus in Mice In a salicate induced mice model it did.
https://clinicaltrials.gov/ct2/show/NCT04066348 Maybe something for you? This is not a light drug though.
TNF-α Treatment of Blast-Induced Tinnitus The related study is recruiting as per yesterday for noise-induced tinnitus. It is changed from...
Resaphene Suisse AG: FDA approval process for tinnitus therapy tinniwell continues Roggwil, July 13, 2022 - Due to the COVID pandemic, work for...
Fully understand.
Great news for you. Keep in mind that the X-Tole XEN1101 studies allowed users to keep using the medicine even after the trial was over. Maybe...
William Blair Biotech Focus Conference 2022 Here is a new Q&A on XEN1101 recorded yesterday. Didn't have a chance to listen yet. Maybe some info...
We have Dr Susan Shore, XEN-1101, SPI-1005 and OTO-313, all completed Phase 2. Dr. Susan Shore will have the shortest timeline, I'd say followed...
OTO-313 Phase 2 is completed on clinicaltrials.gov :rockingbanana:
@Bill_, I see you have created numerous treads throughout the year asking for advice from others. It would be great if you could also provide some...
Happy to hear you are doing better. Still any reactivity to sounds? Can you go out for dinner, take plane flights for holidays? Bedankt!
Hi @Markku, any update on the Sound Pharmaceuticals podcast?
The timelines of phase 3 were shared by Xenon earlier. Phase 3 itself takes 27 weeks starting patient recruiting H2-2022. The total pool is 360...
I wish people would do some desk research first, especially before starting a fundraiser. He has bad tinnitus but he still went to parties...
Based on the last modification date which changed the participation status but did not update the estimated completion, and this was one month...
Keep in mind this is a worst-to-treat population. Like with all sickness, the ones who are the sickest are the most difficult to treat.
Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial TENT-2A study results are published.
Crappy Google translate but: Dosage and administration-Usually, 7.5 g of adult daily is divided into 2 to 3 times and orally administered before...
Thanks for letting us know! I think we shouldn't shoot studies which did not work for someone specifically. I see quite often studies which...
[ATTACH] Well at least we know she was there, first row third of right :)
Hi, how do you manage with Tinnitus in a country like Japan? Last time I visited (prior to tinnitus) I remember how loud the cities were, Jr...
Thanks for the efforts. I do hope there is a slidedeck or presentation to share.
Shore is presenting as we speak, first one that gets a link to the summary, a livestream, press release etc gets a cookie.
Assessment of in-cabin noise of wide-body aircraft This article shows decibel readings of major airplanes: Airbus A330-300ER, A350-900, A380–800,...
Dr. Shore's poster presentation summaries are posted, some new research. https://www.midwestauditoryresearchconference.com Nothing on the main...