Separate names with a comma.
All of what you've said is very true. In their defense though, Otonomy did release Otiprio for swimmer's ear. They later sold it.
Let's hope so!
Invest that in fundamental research instead, like Hyperacusis Research.
It didn't. The higher dosage trials failed (and so did their tinnitus drug, OTO-313).
Otonomy Reports Positive Top-Line Results from Phase 2a...
Then nothing happens with this drug. OTO-413 is there for that.
It is common knowledge that CEOs take business decisions based on mails by random people.
Otonomoy's OTO-6XX is aimed at hair cell "repair" instead of regeneration. Unfortunately the company is in a really bad shape so I don't know if...
If you regenerate the hair cell, the synapse restores on its own.
Around the 29:00 mark.
Reading your post reminded me of Bryan Pollard. He also had an engineering approach when founding Hyperacusis Research. May he rest in peace....
I'm gonna nitpick here lol, but AlphaFold's breakthrough is in protein structure predition, not protein folding.
Which one of those have hyperacusis?
She finished second.
Good point :)
If you would actually read Otonomy's press releases, you would have known this is not the case:
Otonomy intends to initiate a dose-ranging Phase...
They have already stated multiple times that they will do a full Phase 2 first.
Btw, the main author of this research is a Belgian PhD student and finalist in the Belgian PhD Cup. I hope she wins, it would bring quite some...
Belgian researchers are also working on this.
Even if their hearing drug flops, their MS drug might save them; who knows.
Thank you for correcting me. The results will indeed be published in the second half of next year, not the first.
I'm not sure if this has been posted before, but Frequency Therapeutics uploaded a new corporate presentation:...
Why don't you look on their website?
Their Phase one trial was finished back in 2015. The current inflation and interest rate rises didn't cause companies from picking up the drug...
He posted a new update on his blog. He saw further improvements. He's at 9 treatments now.
That's what I think too :(
Something is off when you claim to have such a great drug, yet struggle to find investors. Even when they did partner...
Please properly inform yourself before saying things like this and giving people hope that this drug has a possibility to release in 2025. There...
We need a control group to answer that question.
The study ended about 2 months ago, I wonder when we'll be getting results.
That doesn't really matter, you need a control group to see if the improvement is linked to the placebo effect in any way. Just look at the...
That study doesn't even have a control group.
Some of us hypy sufferers have taken the time to (re)write Wikipedia articles in various languages, to make them more up to date with the latest...
To add: the results of these higher dosage studies will be out this quarter.
As long as the results are good!
We were all wrong, fortunately!
Results are looking pretty good, actually:
87% of patients who experienced ototoxicity in their placebo-treated...
I'm sorry to hear that. I hope you'll get better soon.
Many here will disagree, but you might want to consider wearing earplugs or earmuffs when...
They sure are taking their time to report the interim results on their otoprotective drug, Q2 is almost over.
Afaik we only have a quote of their CEO:...
Xenon Pharmaceuticals Announces Positive Outcome of End-of-Phase 2 Meeting with the FDA | Xenon Pharmaceuticals Inc. (xenon-pharma.com)
Check the full schedule.
Perhaps, or perhaps Frequency Therapeutics has better tech. Time will tell.
Hearing loss company Acousia Therapeutics: first patient with age-related hearing loss treated with ACOU085...
I haven't heard of these guys before. Ting is a biotech company founded in 2018. Their research is still preclinical but it's another biotech...
You seem extremely confident in your advice Michael. Do you have any actual proof backing up your claims?
Frequency Therapeutics still seems to be miles ahead when it comes to actual regeneration then.
How excactly do repair and regeneration differ? Does the mean that a hair cell can be damaged, but not completely broken?
The study ended almot a year ago, I think they've known the results for a while now. But who knows.
At first sight, their speakers seems to have been replaced by Carl LeBel from Frequency Therapeutics. Weird...
Please don't send emails in name of the Tinnitus Talk community. Like others have said, this could backfire on us.
It means the company is basically worthless. What can they even do with 2 employees?
Talking abot a penny stock... The price of one share is 5.6 cents and their market cap is about 500k USD.
Rest in peace Bryan.
Phase 2 trial for depression starting now/soon. Results will be provided sometime next year.
Xenon Pharmaceuticals Announces Initiation of Phase...
Oh I very much agree @Joeseph Stope. That's why I think it can help, I don't think this alone will cure hyperacusis. But again, we can only...
If the theory that Type II nerve fibers send out pain signals because the outer hair cells they're connected to are damaged, then restoring those...
I was wondering why investors don't seem to care about the results. So I compared them with the Phase 1/2 results and this does curb my enthusiasm...
Don't expect miracles from first generation hearing loss therapies.
YEAAAAAAAAH. Next up: OTO-313 :cool:
I was so happy to read about the positive results. Then I woke up.
I hope that means the results are good. But you never know lol.
Lots of companies attending!