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  1. S

    Persistent Tinnitus Spike After Short-Term Clomipramine Use and Possible Congestion

    I have had pre-existing reactive tinnitus for a few years now. I was recently prescribed a tricyclic antidepressant, Clomipramine, for a different issue and took 25 mg for only four days, totaling 100 mg. On the fourth day, I experienced heart palpitations that felt like a heart attack and a...
  2. S

    Sudden Onset of Ear Pain and Burning After Hospital Visit Despite Protection

    I have had reactive tinnitus for a few years now, along with loudness hyperacusis from acoustic trauma. Until recently, I had not experienced pain sensations or noxacusis. I had to go to the hospital for a completely unrelated issue. I am not sure whether it was the road noise or the noise...
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    Suzetrigine (JOURNAVX, Formerly VX-548) for Pain Hyperacusis (Noxacusis)?

    Has anyone tried Suzetrigine for pain hyperacusis or noxacusis? It is being distributed as JOURNAVX by Vertex Pharmaceuticals and was previously labeled VX-548 during clinical trials. The FDA approved it on January 30, 2025. It targets moderate to severe pain by blocking pain signals in the...