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So, if all goes well, we are looking at a minimum of 5-10 years before it becomes available?
I looked at their website and the thread here on Rinri Therapeutics. Have they published any results showing the amount of hearing improvement...
For me, the pain sets in over time. It's usually a few hours, but always less than 12 hours.
It doesn't help with noise tolerance or hyperacusis. Only with the pain. It's an aching/burning pain that's reactive to noise. It gets my pain...
I use Gabapentin whenever my hyperacusis pain spikes. It always helps even in small dosages (max 3x 100 mg daily). It lowers my tinnitus only...
Correct. I was joking. :)
@Justin De Moss has entered the chat.
I can't seem to find Dr. Djalilian's Tinnitus Talk interview. Was it recent? Do you have a link?
I've had three surgeries, all of which were unsuccessful. Patulous Eustachian Tube symptoms include autophony, hearing your voice in your head,...
I have it. In my case, it's due to a Patulous Eustachian Tube. It's a terrible condition to have that makes my tinnitus seem like a walk in the park.
Sorry that the improvement didn't last. How did you decide on taking 15 grams? Did you try less first? Why not try it again?
0% anger. 100% despair.
I'm in LA and have some major imaging labs near me, but I have never seen a Canon MRI. After this open MRI experience, I will still try to avoid...
MRI: https://www.westwoodmriandimaging.com/functional-mri Sorry, I meant to say orange earplugs. Those foam ones.
I just did an open MRI. So much for it being open, as my head was still 3/4 in the tube. I wore the pink -35 dB earplugs with the wax -10 dB (?)...
Debunked fairly well here: [MEDIA]
Does he do multiple injections in one treatment? Does he numb your eardrum?
Only in years.
Is there anything preventing FX-345 from affecting frequencies up to 20 kHz? Or are the higher frequencies more difficult to treat?
Yes. Once and never again. It was 250 mg NAD IV that took about 45 minutes. I almost stopped it midway. Very painful stomach cramps, which lasted...
No improvement in tinnitus for me now that it's worse. When it was minor, there was some improvement. I first started Nicotinamide Riboside around...
When my hearing loss was minor, I know Nicotinamide Riboside improved it. Now that it's worse because of noise exposure, it has less of an effect....
"A" for effort. Why not Nicotinamide Riboside?
Stop while you are ahead. Just two sessions of HBOT wrecked my Eustachian tubes permanently.
For those NAC addicts out there, PharmaNAC is now available online. It's considered one of the best forms of NAC as its effervescent tablets...
They didn't have the $19.5k option when I last checked but that was a few years ago. The $58k gets you 200 million stem cells.
I saw two pricing options from StemCells21, $38k and $58k. Is that what you have?
Didn't we accuse the FX-322 participants of lying in the WIN tests to get into the trial?
So no improvement in high frequencies as Meniere's only affects the low frequencies?
I can't find the two mini-trials on clinicaltrials.gov, do you know if they are listed?
Does anyone know who the doctor is in Seattle?
Yes, my tinnitus is noise induced. Nicotinamide riboside doesn't help everyone, but it's worth trying.
Would you consider any improvement in the thresholds a success or are you trying to reach a certain dB?
Best of luck to you! How bad was the pain? Are you getting this treatment mainly for hearing loss?
Thank you.
Hi. Sorry that you are going through this PET hell like me. It makes tinnitus seem like a walk in the park. My doctor in TX is Marc Dean. He is in...
@Seabert, I'm curious as to why you chose NMN over NR?
Do you honestly believe that all three could be complementary to each other?
500 mg-650 mg.
I can relate. My hearing loss has cost me a 30-year career. I was at the top of my game. Now I'm starting over after losing my one skill. My life...
Did you ever go to see Dr. Poe for your PET?
Piracetam would always temporarily lower my tinnitus for about a day. But it has recently caused GI issues so I had to stop taking it. I never...
Well-known in the nootropics world, Nootropics Depot is legit.
More so with cognition. Especially with verbal fluency. It does have an effect. It may give me a small and temporary reduction in tinnitus.
I was accepted into the study based on a preliminary phone call. Dr. Djalilian was booking into August already. Did you say you are going to...
I have not tried Semax. I do like Piracetam though.
Thanks. I've been going the other way starting at 0.1 g to 0.05 g and now maybe 0.025 g. Most I've done is 0.15 g. I find I get fatigued later in...
I tried Patulend. It's like snorting battery acid mixed with chili flakes. All for a few minutes of relief. And you thought tinnitus was bad?...
Agree 100%. Only two sessions wrecked my Eustachian tubes and gave me a condition called Patulous Eustachian Tube. Just like tinnitus, there is no...
What are your thoughts on this study?
Yes. Stacking is a common term meaning taking multiple supplements at the same time. FYI, I never met a stack I didn't like. :)
Do they recommend stacking all three?
Evaluation of vinpocetine as a therapy in patients with sensorineural hearing loss: A phase II, open-label, single-center study Abstract The...
Amazon is pulling NAC. Amazon confirms plans on removing NAC supplements Amazon confirmed this week it’s in the process of removing from its...
I tried Cerebrolysin and was able to administer it using sub-q injections. I had to stop it after a few weeks as it increased my insomnia and...
A bigger issue with Psilocybin is accessibility for most people. I was lucky enough to find a reliable source. But what I also learned was how...
I've tried it and still use it. It's called the Stamets Stack, and it's popular in the micro-dosing community. Microdosing Psilocybin Mushrooms...
Sorry that you have had a negative reaction to microdosing. I've been microdosing Psilocybin on and off for the last few months and it hasn't...
Noted biohacker, Tim Ferriss, recommends 200 mg of Huperzine A 30 minutes before bed. He says it can increase REM sleep by 20-30%....
I just bought some Glycine which I will stack with my NAC. I don't see any advantage of using GlyNAC when it is essentially the same thing....