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As I mentioned earlier, I am currently browsing university websites based on the 2024 Shanghai Ranking to find information about tinnitus research. Here is a piece of news from Columbia University, which is ranked 8th. To be transparent, I should note that there were earlier posts about this...

I am currently browsing each university website based on the Shanghai Ranking to find information about research in tinnitus...

Our results indicate that a genetic predisposition to anxiety and depression can significantly increase the risk of developing tinnitus. https://link.springer.com/article/10.1007/s12070-025-05618-x

Yet another study exploiting the UK Biobank. This one is quite interesting and relevant. https://journals.lww.com/otology-neurotology/abstract/9900/integrating_expression_quantitative_trait_loci_and.840.aspx

To be honest, I have no idea.

They have just made a major discovery: https://med.stanford.edu/news/all-news/2025/05/orange-cats.html More seriously, without intending to be rude, I think the Stanford website is not well organized. For example, there are two different pages for the Stankovic Lab: If you do not go through...

The 2nd International Conference is scheduled for October 2, 2025, with confirmed speakers Professor Thanos Tzounopoulos and Dr. Kelly N. Jahn: https://hashirtinnitusclinic.com/event/2nd-international-conference-on-pharmacology-gene-therapy-for-tinnitus/

Yet another team. It might be wise to separate these different teams into individual threads at a later stage. https://www.kcl.ac.uk/news/kings-researchers-received-aria-precision-neurotechnologies-programme-funding Mosaic Neuropharmacology with Focused Ultrasound Dr Antonios Pouliopoulos...

In our tinnitus animal models, the tinnitus was eliminated during the deactivation of the amygdala projection. However, the tinnitus returned immediately once the pathway was no longer deactivated. https://digitalcommons.pcom.edu/research_day/research_day_GA_2025/researchGA2025/34/

I came across an article written in French by a French magazine. I couldn't find an English equivalent, so you may need to use a translation tool. I'm sharing this article because it includes interesting graphs that do not appear in the research publication from PNAS (at least not in the...

Hi @Hazel, were you aware of this? It's in your country: https://www.tudelft.nl/en/events/2025/tu-delft/06-jun/symposium-the-sounds-of-progress-engineering-better-outcomes-for-tinnitus-and-hyperacusis

I’m taking this opportunity, through this article and discussion, to share something I haven’t mentioned before. Unfortunately, my tinnitus worsens when I exercise. I suspect that my neurons, which already fire spontaneously, become even more active due to the increased blood flow. The release...

I realized that there was no Polysomnography and Sleep Disorders thread in the Research News section, so I created one. Analysis of Polysomnography in Patients with Sleep Disorders Accompanied by Tinnitus

Fellow sufferers, does anyone here have the opportunity to access the full text to learn about this mysterious, miraculous pharmacological treatment? It is unfortunate that it is not mentioned in the abstract on the Springer website. https://link.springer.com/article/10.1007/s12070-025-05478-5

Like you, I am not one of those people whose tinnitus decreases in loudness or distress over time from its onset. Short- and long-term changes in auditory sensitivity and tinnitus distress between acute and chronic tinnitus: longitudinal observation in a community-based sample

Well, to me, the most important information is figure 2E: evolution of tinnitus severity. https://www.nature.com/articles/s41467-025-59445-3

Role of Proton Pump Inhibitors: https://pmc.ncbi.nlm.nih.gov/articles/PMC12022890/

A publication discussing neuroinflammation and tinnitus, both acute and chronic, in general. https://www.scirp.org/journal/paperinformation?paperid=142056

Tinnitus, noise exposure and the risk of dementia: a prospective cohort study based on UK biobank Get access Arrow

https://journals.lww.com/ear-hearing/abstract/9900/investigating_the_role_of_working_patterns_in.419.aspx

The link provided by @RODRIGO does not work anymore, but here is a related publication.

Weird thing: on this website from a French practitioner, hyperacusis and tinnitus are listed as exclusion criteria: https://www.lartdesecomprendre.com/conseils-et-contre-indications/

Can Pupillometry Help to Choose the Right Nerve for Tinnitus Reduction? Once again, a new article from researcher Henk Koning. I really do not understand his research. Maybe someone can explain it to me?

Work absence and ability in tinnitus patients: the role of hyperacusis and tinnitus severity

It is always the same dilemma. Is it useful or harmful to post this kind of publication? I personally think it is useful to keep awareness of our torment, even if it has already been said, but it is up to the moderators. Systematic review and meta-analysis of the correlation between tinnitus...

The important information is this: A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES

Plasticity of the auditory cortex and brainstem in surgically induced unilaterally deaf adult humans with and without tinnitus Highlights The unilaterally deaf (UD) with tinnitus group showed high ipsilateral hemisphere cortical auditory evoked potential amplitude. This increased sensor level...

The PDF publication below reminded me of this thread. By the way, searching otolithlabs.com with the keyword tinnitus returns “no results found.”

Yet another team is trying to solve the inner ear delivery issue. Injectable polyplex-loaded glycol chitosan thermogel for efficient and safe inner ear gene delivery Highlights A novel RH-PAMAM G2 polyplex-loaded HGC thermogel system has been designed to enable effective gene delivery to the...

At first, based on the title, I thought this publication was about experiments conducted by a biolab. Then I realized it was another biobank informatics request. The new thing for me was discovering the existence of the GeneCards database (were you aware of it?). It seems to be a different...

Completed. However, I must confess that I likely lowered the averages of this survey significantly because I am excessively fearful.

@Joeseph Stope, thank you very much for your compliments; I am very flattered. As I have already mentioned on this forum, it is thanks to a Google Scholar alert with the keyword “tinnitus” that I set myself the goal of reviewing the publications (around 10 are released almost daily) and...

So, there is a biological difference between mild tinnitus and severe tinnitus: Neural Mechanisms of Tinnitus:An Exploration from the Perspective of Varying Severity Levels And there is a biological difference between acute tinnitus and chronic tinnitus: Decoding Tinnitus Progression...

Tinnitus, lucid dreaming and awakening. An online survey and theoretical implications

https://link.springer.com/article/10.1007/s00405-025-09246-7

Conclusion: Obstructive Sleep Apnea is a risk factor of tinnitus. https://link.springer.com/article/10.1007/s11325-025-03243-0

Here's a new article from Will Sedley and his team: https://link.springer.com/article/10.1007/s10162-024-00970-1

@victoria9273, this is a new related publication, for your information: https://www.mdpi.com/2227-9059/12/12/2837

For those who are interested in this topic: Brainwave entrainment using binaural beats stimulation: Exploring the treatment efficacy in individuals with tinnitus having normal hearing sensitivity

Highlights Noise exposure induced changes in various cerebral regions (cortex, thalamus, hippocampus, amygdala, striatum and cerebellum). Cerebral changes result in disorders (tinnitus, anxiety, depression and cognition impairment). Several antioxidants provide protective roles against noise...

I wasn't sure whether to start a new thread or add to this one, as my experience relates to two specific points: At least twice a week, I actually hear my tinnitus during my dreams. It's "wonderful" (ironically) to realize that even in sleep, tinnitus can still bother me. In these dreams, I...

Although I am French, I am committed to keeping Tinnitus Talk in English for the benefit of everyone. However, I wanted to share information specifically for French speakers: Höra, an app that offers a sound level meter and a speech-in-noise test. This app is supported by the French Foundation...

See my ancient post. To be more precise: I had been taking 8 drops of Clonazepam for over a year, following the advice of my oto-neurologist, without any noticeable effect. So, with my oto-neurologist’s approval, I decided to gradually increase the dosage. At 21 drops, I began to experience...

We all agree that finding a cure is essential. The title of this thread could be improved. I might have titled it something like: “Comprehensive Publications to Explore Brain Systems (including the oto-neurologic system) for Understanding the Pathophysiology of Tinnitus.” This title would...

Finally, some researchers revisited this fundamental question and conducted this experiment. Unfortunately, the results indicate that tinnitus may be even more complex than we previously thought: https://www.researchsquare.com/article/rs-5014033/v1

Sorry for my late reply. Just take a look at my investigation: https://www.tinnitustalk.com/threads/caroverine-and-inner-ear-diseases.1352/

Yet another suspicious hint of the Caroverine mystery: https://journals.lww.com/jfmpc/fulltext/2024/13100/effect_of_oral_caroverine_in_the_treatment_of.80.aspx

Hello everyone, I wanted to make a small contribution by (re)highlighting some exciting information. Unfortunately, there’s no English translation provided by the researchers for the link below, so you may need to use a translation tool: World Premiere: The Brain Revealed Like Never Before...

I'm not sure where to share this publication, but I believe it's worth reading (sorry, only the abstract is available) since it studies over 3 million workers. Perhaps the full article will provide information about tinnitus prevalence, as I received it through a research alert with the keyword...

I'm sorry, but I just came across this publication, so I do not have any further information. Feel free to contact them.

It is a pity the article is behind a paywall. Compared to this thread, similar parameters are acute tinnitus, the hypothesis of neuroinflammation, and rodents. Dissimilar parameters are noise-induced tinnitus instead of salicylate-induced tinnitus and Rolipram (an old drug) instead of TNF. →...

→ The Current State of Tinnitus Diagnosis and Treatment: a Multidisciplinary Expert Perspective

→ Efficacy and safety of SENS-401 in sudden sensorineural hearing loss: The AUDIBLE-S randomized placebo-controlled phase IIb trial

Effectiveness of transcutaneous vagus nerve stimulation for the treatment of tinnitus: an interventional prospective controlled study

FYI: I tried Gabapentin (prescribed by my psychiatrist), 2 pills of 100 mg in the evening for 3 months (July, August and September). No effect on tinnitus, no side effects either.

FYI: I took Tegretol 200 mg in the evenings for 3 months (January, February and March 2022). It was prescribed by my psychiatrist. No effect on my tinnitus. No side effects.

"Ablation of Tbx2 in postnatal, largely differentiated IHCs makes them transdifferentiate directly into OHCs, replacing IHC features with those of mature and not embryonic OHCs." I don't get it. Can someone explain to me? Do we keep this TBX2 in our body (postnatal)? Because nothing happens...

I remain skeptical: gene-editing seems to me like the Pandora Box (cancer triggering...)

This news gives me an amusing thought: the possibility, in turn, of virtually torturing my tinnitus avatar, just to get revenge, as a kind of stress relief. But the worst is that it would be able, given the principle of this virtual reality, to shout in the headphones in return and to hurt my...

Hi, sorry for the delay. Looking at my old blood tests (back to 2013/2014), my maximum dosage was 3,040 mUI/L (according to the tests, limits are 0,270 min and 4,200 max).