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10 years to get to a phase 2, god damn. What a joke Hough is when it comes to actualizing their products. They should have spun their research...

Hey Steph, this could be an endocrine issue. Can you get checked out for things like Cushings? Cataracts and hair loss are sometimes symptoms, and...

Yes, I still do. Nothing has really changed.

keith you have beautiful eyes.

@Ed209, this is super random but can you pick a number for me between 1 and 15. I promise it’s not for something weird.

Holy shit Zug, you got promoted from evangelist to lawyer, and you didn't tell us? wtf man, we would have thrown you a party.

I’ve been using Discord more and more to distract myself, but there’s only so much I can do before the walls start closing in around me again...

Say what now Lol no. I think you missed 99% of the thread tbh.

For anyone curious, what that guy is describing is the MOC reflex. Basically you have a feedback loop where sound enters the ear, runs through the...

Interesting. Good to know my dad is in hell. TIL.

This is giving me strong Tynnyfer vibes.

I think too some people, myself included, find solace in research. It makes me feel informed, which by extension makes me feel empowered. Others -...

It absolutely sucks doesn’t it. Every medical procedure feels like navigating a mine field when you have shitty cochlear problems. The person who...

You said 45 degree angle correct? All four of mine were growing in at 90 degree angle so fully impacted on all sides. For my case, I had to get...

Yep, here they be. Relation of focal hair-cell lesions to noise-exposure parameters from a 4- or a 0.5-kHz octave band of noise Distribution of...

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Who wants to tell him?

Wow, just wow. Absolutely phenomenal. Thank you for this. I wish something like this would be available in ENT offices. Also might I suggest an...

I believe in you Zugzug. I also found leaked footage of you and Diesel purchasing that RV. [ATTACH]

It was a cat xD From the CATS musical. I highly recommend the old version. You can find it on YouTube - it is a trip.

Well yeah, no shit. What did you think I meant? That Diesel, Zugzug, FGG, and Aaron91 would be concocting makeshift FX-322 out in a random back...

This is silly imo. Science is heavily concerned with minutiae. Imagine if after the flawed launch of the Hubble Space Telescope, the engineers and...

Ah, that makes sense. What I don’t understand then is why they would say they would move forward with single doses for FX-322 specifically...

Okay, so I could be completely, utterly off base here. But this weirdly enough sounds like a scheduled tweet to me. I used to do social media for...

If you can (and I don’t pretend this isn’t extremely hard) I would at least wait until they release that new form of CI that uses light. @FGG...

Byproduct of improved cochlear input at the proper frequency. If you don’t parse out all the permutations of what “improved hearing” actually is,...

It’s important to understand what structure is being fixed and to what extent, so that we don't keep seeing the same erroneous “I knew FX-322 was...

This is what really, truly hits me. My worst case scenario was that Phase 2 would show the same benefits from Phase 1, with no real additional...

I recommend reading this. Keep in mind, as FGG has said, audiograms do not measure IHC loss. The article is mostly focused on synaptopathy, but it...

I wonder if needing the IHC to be regenerated first is due to the specifics of the progenitor activation pathway. Perhaps because it works similar...

That makes sense. When they tested above 16 kHz for me it sounded like “shhh shhh”. It wasn’t a pure sine wave. I wonder if that’s part of the...

I wouldn’t use the audiogram as a means of assessing tinnitus improvement. I have substantial notches that match my tinnitus tones. But they don’t...

Interesting question... I suppose it would depend on how afraid you would be about getting “caught” should any discrepancies surface and how aware...

Don’t tempt me, I will waste money on this.

After all this (and having read the various - and extremely informative - breakdowns from @Aaron91, @Diesel, @Zugzug and others) I’m still more...

This is darkly hilarious to me because it’s like they never stop and think “hm, maybe it’s so variable, because I don’t know, maybe some have very...

Eh? I’m confused about this, not sure why I gave you this impression. I was only speaking from my own experience that waiting for a HL drug to hit...

Can we like, maybe not call the drug dead until we have the full readout, and can parse through all the data? Just a thought. I swear this forum...

I actually fear I might have been unknowingly complicit in the whole fraud thing, if that turns out to be truly legitimate. Most people were not...

Columbia is actually working on this. 3D-Printed Microneedles Create Precise Perforations in Human Round Window Membrane in Situ 3D-Printed...

I hope this isn’t coming across as me making light of the situation... I, like several others, did not have high hopes for greater penetrance...

The only data point I can think of off-hand is Ebselen, which becomes far less effective for ear inflammation at higher doses. But that drug is...

Not in vivo. If we had that kind of diagnostic tool we wouldn’t be working solely around audiograms.

I’m still trying to square away these results with the phase 1 data, because this is all very confusing. I didn’t expect phase 2a data to be...

Yes, correct.

I should clarify. My audiologist didn’t know that this would be submitted as consideration for the FX-322 trial. It wasn’t a deliberate...

Not necessarily. When I did my word score testing I said “I’m not sure” at several points and then my audiologist increased the decibel level so...

Wow... this just breaks my heart... I don’t really know what to say. I wish he could have held out for a bit longer for some of the drugs that are...

I unironically do not want him to leave this thread. He is low key brightening my day every time he posts, due to the sheer amount of meme...

OMG... I didn’t even realize it was misspelled. My brain straight up auto corrected it...

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I never really knew what it was like to have a hero or someone you deeply admire, and then @FGG dropped onto the forum and I was all “oh... OH,...

[ATTACH] FX-322 2.0. But in all seriousness, I believe vibrational resonance is being looked in to by a few other companies as a means of drug...

Did I miss the meme party? [ATTACH]

I believe this quote here is also kind of concerning, and part of the reason why others are giving you a hard time and claiming you have a...

@FGG is obviously the most sinister and Machiavellian of our rag-tag crew.

I would also like to know when my beautiful and lonely 7 GME shares will finally land on Pluto, plz and thank you.

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To be fair, if you read tinnitus research papers from the 80s and 90s it’s interesting to see quite a few of them say one of the main causes of...