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Lenire seems to be exploding in name recognition and popularity, and I'm starting to question whether the minuscule sample size we have here—from...

I've often wondered how sustainable it is to cycle benzos indefinitely without building tolerance and withdrawal. Maybe once per week? Twice per...

There's another HCN modulator called Guanfacine, which is an a2-adreno agonist like Clonidine used for ADHD. I tried making a survey here about...

Did Paxlovid have any effect on your tinnitus?

Nimodipine is used pretty exclusively for hemorrhagic strokes. It's not something used for chronic blood pressure.

It's between this and a beta-blocker for me. It would be great if drug surveys on Tinnitus Talk had a larger sample size given the size of this...

Lenire didn't take long to get to US market after FDA approval; I think it was about a year? Auricle is seeming like mid-2025.

My hyperacusis has been almost non-existent for the last year. It used to be so bad the sound of my own voice would hurt my ears.

Do you have a source for this? I looked into this a few years ago and I remember the results were all over the place.

Depends on what proof means. The TENT-A2 studies show a definitive improvement in TFI, but I forget why it was dismissed as p-hacking by some...

I get this exact thing when I'm stressed. Thankfully it never lasts more than 3 weeks at a time. It seems to be the type of sound that goes away...

Just the term "tinnitus memory" is an assumptive premise. Are they saying it happens once and then gets stuck, or what? It's all just speculation...

They're scary, whatever they are. How are you doing now?

Stories like these are enough to scare me away from looking into cochlear implants. They do give some people tinnitus, maybe because it's such a...

This is exactly what OTO-413 was I believe, are there any differences?

Don't forget that DBS involves an MRI scan. They're insanely loud and some people have claimed it's spiked them. My scan didn't seem to affect my...

I believe it was in a video interview with the CEO Ross O'Neill, from like 5 years ago. Not saying I would risk using the device personally, but...

Interesting, I would love to hear from any members that take Metformin. It's one of the few drugs that has been shown to reduce the chance of...

I was referring to their tinnitus.

I remember reading that hyperacusis patients have the most success with Lenire.

Reminder that this process involves MRI imaging. That's 20 minutes of 105-110 dB.

Vinpocetine is the only compound I've ever seen that has actually been shown to improve hearing over time. There are other compounds that have...

Neosensory recently published a controlled trial of their device and found it to be quite effective for tinnitus. What do you all think of this?...

The more I read about Dr. Shore's device, the more my intuition is telling me it won't help with low-frequency droning, humming and rumbling type...

@Tau, did this work for you?

Is it possible that XEN1101 could cause tolerance and subsequent withdrawal in a way does the opposite of its intended effect? Many of the drugs...

LDN is systemic, there would really be no need for intratympanic administration. As my audiologist used to say, the ear bone's connected to the...

I went down this rabbit hole last year. The Siemens Aera 1.5 T with Quiet Suite (software setting) is genuinely pretty quiet, but you do need...

10.9 dB reduction would be wonderful. For those of you that don't know, it's approximately the difference between standing 10-feet from a noise...

I wonder if the auditory stimulus could be a broadband sound that incorporates various frequencies. I'm thinking I'll just have a full on symphony...

I've been around sounds throughout my life that would put construction workers to shame. I was once exposed to an AR-15 shot from 12 feet (~140...

Liam's basically a one-trick pony that only talks about diet. He's not wrong that fasting can quiet tinnitus for some people. The salicylate thing...

There were only 3 requirements for the last trial: have had bothersome tinnitus for at least 6 months have no more than a mild hearing loss...

Sorry if you've mentioned it before, but did Retigabine help your tinnitus?

March 19th, 2013. I was dizzy for that entire week. I noticed sometime in the evening I heard a static sounding "sssshhhhhhhhhh". It never went...

I can remember an interview in like 2018 where the CEO Ross O'Neill referenced those trials as a proof of concept for MuteButton. Those trials...

Isn't it strange that Lenire never explicitly required "somatic tinnitus", even though the University of Minnesota trials it was based on did...

It varies, but for me it was about 3-4 months of the worst symptoms. Just make sure to rest your ears and maybe take antioxidants and control...

Yes. Then it happened again. Then again, and again. It's a remission game until a cure is available.

To this day Hubert Lim talks about Lenire like it's a miracle invention. I wonder if they really expect to compete with Auricle. Could they be...

Or less. Or 100%. We don't know and neither does Dr. Shore.

I've been reading about this and apparently you can avoid some of the initial side effects of LDN by starting dosing around 6 mg. Some points from...

Some of us are in both groups simultaneously. I have a narrowband sound related to my TMJ that I can modulate, but I have multiple broadband...

Keep in mind that improvement lasted 12 weeks past the treatment cut off. That's a very long time for the placebo effect to occur, and I have a...

I hope they would know better than that. I know some people on here can handle loud noise just fine but others would be leaving that test with...

I'd be willing to bet that volume is the biggest variable when people take the TFI. I've taken it myself, and there are questions like: - "Do you...

I'm more concerned with what works. If people were saying that Lenire made their tinnitus go away, I wouldn't care about the lack of placebo.

Regardless of what the studies say, there is still a chance of worsening tinnitus, in a similar way that Lenire is a complete gamble.

A lot of these high blood pressure drugs can overcorrect enough to give you hypotension, which can also cause tinnitus; ears are just sensitive to...

Dr. Dirk de Ridder prescribes this medication for some of his patients. I think it would be good for the community to have a larger sample size...

Where are we on the question of what qualifies as somatic tinnitus? Dr. Shore's trials only recruited people with this pseudo-etiology, but she...

It actually seemed to settle down. I didn't have any of these episodes at all in the last month. I don't know what caused it, I think stress and...

Look for a good audiologist. ENTs will know more about the latest sinus infection cure. My audiologist knew about Auricle back in 2021; find...

Has LDN had any effect on your tinnitus? I have a bottle of LDN in my closet, I'm just too paranoid to try it, mostly because of the anecdotes on...

Blood pressure 110/70, no meds at all. This has been going on for 6+ months, so I'm guessing it's autoimmune in nature. I see Prednisone caused...