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I see that you joined in late January 2025, so I conclude that your tinnitus onset was sometime in January 2025, about five months ago. You are still in the acute (early onset) phase. Your chances of it getting better are pretty good. It would be helpful to have a good ENT who understands...

Glow-in-the-dark axolotls reveal a clue in the mystery of limb regeneration To cheer you up and divert your attention from tinnitus: a) It is all about retinoic acid! Now why did I not think of that! b) Humanity has been evolving in the wrong direction. We should reverse course and develop...

Well, as I have said before, it is never too late. Fire up the motors and inject the substance again. See if it works this time.

Hi Kam75, I'm shocking ignorant about computers. I think you added a lot to the dialogue with JoeCync... could you explain to me what "following you" means? Sorry that I'm so ignorant. Vive la France joeseph Stope

Maybe we should view it all like a football match. We all want our team to win the World Cup, but it takes a few years to train a good team. With diligence, hard work, and a good trainer, a team eventually develops that can coordinate things well. At some point along the way, we may even get a...

What is the name of that movie again? One Flew Over the Cuckoo’s Nest! That is it. Of course, that movie was about the inmates living locked up on the funny farm. There is nothing crazy about us, right, Napoleon? Ha! Just kidding, @Tom Cnyc. But let me say that you are one very lucky person...

Progress, progress! Now we can deliver the goods to the correct address. The only thing left to do is produce the right goods. :popcorndrink:

First of all, I want to say a big thank you for taking the time, making the effort, and having the patience to share your story and clarify the parts that were difficult to understand. Hang in there—or maybe I should say hang in here. As long as it does not push you out of the “sweet spot” of...

Jehoshaphat! The medics should examine two individuals in depth: @Kam75, who exposed himself to moderately loud social gatherings. As a result, his tinnitus and hyperacusis worsened significantly—to the point of becoming almost unbearable. @Tom Cnyc, who did much the same but to an even...

Duh… me again. I was shooed out of the library yesterday while I was in the middle of delivering my saga on one of the computers. That might have been a good thing, though, as it gave me a day to mull everything over. And really, when I think about the entire ongoing tinnitus experience in...

So sorry to see you in this state. Maybe my experience can shed some light on the situation, but above all, you should find a good ENT or audiologist with experience in treating tinnitus and hyperacusis. There must be someone in Paris. Perhaps Frédéric, the super intelligent red haired guy who...

I’m starting to lean toward the idea that perhaps the solution to the tinnitus problem lies in solving the hearing loss problem. A more holistic approach might be the key. So how do you learn to jump two meters? Simple — just learn to jump four meters, and two will be easy. 🙄

I’ve been mulling this dialogue over in my mind. Some patients benefit enormously from getting on with life and can handle loud environmental noises without much difficulty. Others, especially those with reactive tinnitus, may do fine until something like an ambulance passes by with its siren...

You certainly present a strong argument. But let’s imagine you are giving advice or a talk to a group of people dealing with reactive tinnitus and hyperacusis: “Everyone, try to forget your tinnitus and get on with your life. That starts with ignoring the spikes that unpleasant sounds can...

Your contribution is much appreciated. The time and effort you put into explaining your situation, and the depth you went into, makes for a very good and thoughtful read. Without a doubt, it will bring hope to many people on this forum. However, there was one small part of your summary that...

If it is already being used as an unconventional alternative treatment, then by all means, continue exploring it. For that matter, do not stop with magic mushrooms; there are many other substances out there that could benefit from proper blinded clinical trials.

Congratulations! Wishing you a long and happy life. Just one small point that I think is important to mention: If every one of us, man or woman, were to follow your advice and simply ignore the intrusive sound within and the pain inducing noise of the environment, let us suppose for a moment...

It is possible that my patience and optimism with this institute are now old-fashioned. I have become too accustomed to expecting breakthroughs from US research. In past decades, Americans were at the forefront of innovation — they had the funding and a can-do attitude. It seems like Elon Musk...

I think this is something for the courageous, the emergency unit, and the statisticians. I do not want to discourage anyone, but does anyone know the success rate per hundred? Specifically, how many cases of chronic tinnitus have been cured permanently? What is the body count? What is the...

I beg to differ. I seem to recall that they received a substantial amount of funding some time ago. I agree that it is discouraging that all they seem to have produced so far is public relations. This is America, where anything goes. If they managed to secure significant research funding...

The authors, specifically the research team, appear to be from China, Korea, or similar regions. I remember considering a treatment called "Ganglion Block" in the early nineties, during the early onset of my condition. If I recall correctly, the pioneers of this treatment were Dutch doctors...

Life can get so technical. For the sake of completeness, one might consider adding ANC headphones to the discussion. ANC stands for Active Noise Cancellation, and a good pair can cost around 200 dollars. These headphones block or reduce outside sounds while allowing you to listen to music from...

Straight to the point as usual. One glance tells me you are all feeling down about delays, excuses, confusion, and similar frustrations. Well, I just experienced about an hour in another world, completely free of my constant tinnitus. I got completely absorbed in a book about a young woman's...

My sympathies. You are not alone out there. My habit, though I am not suggesting it is better than yours, is to use earplug-style hearing protection, like the 3M Peltor type (from Minnesota Mining and Manufacturing). It does an acceptable job of protecting against high-frequency noises. The...

First, let me express the hope that this is not off topic. I live in the provinces in a place that is no one-horse town, although it has been trying to call itself a city for the last 1000 years or so. Nevertheless, along with a city hall, hospitals, fire brigade, a university, and so on, it...

https://www.sciencealert.com/a-tiny-piece-of-mouse-brain-has-finally-been-mapped-in-mindblowing-detail Just a quick note to say that the scientific community is buzzing with the publication of an extensive study on a portion of a mouse brain. It includes all the electrical activity, wiring, and...

Jay, I am far from being an expert on this subject, maybe more hysterically accurate than historically accurate. But I seem to recall them being involved in some way, at least on the fringe, in the development of the first cochlear implants. That was certainly a step forward for those whose...

So it is the psychological distress from hearing loss that increases the risk of a heart attack, then.

Maybe I did not express myself clearly. If this AC102 works by mending hearing damage, then it is useful for those with recent noise exposure. However, even for people with chronic tinnitus, where it is much too late to repair damage from years ago, this could still help. If someone with...

First, let me acknowledge that you received two emojis of approval for your post above. But as always, I tend to be the contrarian who wants to argue a point. I would like to highlight the depressing reality that modern city life seems to be getting noisier and noisier as the years go by...

There is some merit in what you say. Back in the 1990s, a story circulated that Ronald Reagan had tinnitus, supposedly from a gunshot. When he was President, he asked some of the top doctors if they could do anything for him. The reply was, “No, Mister President, I’m sorry, we can’t do...

Careful there! You might be causing a lot of people in supervisory positions to go red in the face, or worse. 😬 All those research hours, all that time, effort, and sweat. Just kidding. It’s about time the discussion of “What went wrong, what went right?” made its way down to our level. I’m...

I am bowled over by the depth of your scholarship. My non-medical response would be: “Look and see!” An examination of a dissected cochlea should provide a quick answer, or perhaps someone has already done this at some point, somewhere. There is also the recent innovation of the Optical...

Hello, I am a long-time sufferer of tinnitus and hyperacusis. I was recently exposed to a series of alarms, including a fire, smoke, and shop alarm. Since then, my hyperacusis seems to have become more sensitive to noise, and my tinnitus has settled into a new baseline, you could say a...

Not much luck on my end. His inclusion criteria? All I can find is that he distinguishes whether the first onset of tinnitus was when the patient was younger than 43 or older than 43. Is he trying to show that age-related tinnitus or hearing loss (presbycusis) does not respond to the treatment?

Hang in there, bro. I hope work improves, and I’m praying for a cure or at least something that helps alleviate it. Right now, I always carry a pair of 3M Peltor hearing protection with me. If I see something loud coming, I put them on. I’m not sure if that’s the right thing to do, though.

I took a glance at your introductory post, which says the onset was last summer. Most people seem to improve somewhat after the first few months. Back when I was learning the ropes, they used to say that if you still had it after two years, then it was considered chronic. So there is still hope...

Nail on the head, @Scruffiey! Even before my first tinnitus onset, I had to live with very sensitive hearing. After I developed tinnitus, my hearing sensitivity worsened—hyperacusis or reactive tinnitus, I think it’s called. So, I did my best to live a sheltered life over the years. Recently...

It’s still early days, and it remains to be seen what will come of this new innovation. But experience tells us that when technologies converge, major breakthroughs can happen in how we understand things. I have high hopes that once Bionics Labs begins marketing their apparatus and the Optical...

This OCT technology scanner dates back to 1991. It is unfortunate that it has been widely available in most eye doctors’ offices for routine inspections of glaucoma and macular degeneration for so many years. Yet, thirty-four years later, someone is only now considering adapting it for auditory...

Well, they should restart the process. There is no need for more double blind placebo studies. Take ten random patients. If it works on the first, the second, and so on—curing all ten out of ten, or at least not harming any of them while curing 50 percent—I am sure their stock price would rise...

This sounds reeeeally big, maybe even a breakthrough? Years ago, I read a scientific article describing how inner and outer hair cells resemble a microscopic wheat field. However, they could not be viewed in vivo because the cochlea is one of the hardest bones in the body, and its proximity to...

The tinnitus I have is more of a ringing, and I would say it’s on the left side—either in my ear or maybe my brain. It’s constant 24/7 but reactive to loud noise, certain herbs like basil, rosemary, and oregano (due to their salicylates), as well as colds, the flu, or headaches. These all spike...

Hey, Big Spender! No, just kidding. It seems this paper has caused a lot of excitement. A reason to celebrate? Well, I hope so, but don’t bet the farm on it. I am inclined to look at it—how would I explain it? Maybe the way an American looks at the US national soccer team. They are not very...

Speaking as someone who habituated to tinnitus back in the 90s through TRT but never fully adapted to noise sensitivity or hyperacusis and then later experienced a return of tinnitus, I find the work of the Bionics Institute intriguing. For example: a) If they measure the tinnitus volume of a...

@Mathilda, mulling over your story and comparing it to the days when I was bouncing from doctor to therapist, some things you said brought back memories. You mentioned a 20% reduction in tinnitus—I’m happy to hear that, and I hope it lasts. About 25 years ago, I did a therapy program at a...

The modern world is becoming louder rather than quieter, increasing the risk of further hearing damage. Whether due to acoustic trauma, aging, a flu virus, or a pharmaceutical side effect, the chances of experiencing hearing issues grow with each passing year. If there were a drug that could...

My sympathy. The brand of vaccine might have played a role, the company that manufactured that particular vaccine. In situations like this, where a new virus emerges and multiple vaccines become available, it is often only afterward that we learn which one may have had unintended effects.

This could be very important. Now, all we need to do is go back and test those failed pharmaceutical and biopharmaceutical candidates using this new delivery method. All you tinnitus punters out there, get yourselves on the list for the upcoming trials! I am volunteering for the placebo group...

Well, the Donald is older now than Joe Biden was when he started. If CNN is anything to go by, Elon Musk’s push to downsize the federal government is leading to all sorts of blunders—like firing the people in charge of nuclear defense, the ones overseeing bird flu control, or those responsible...

Is Ebselen the new Viagra? Just kidding, but it would certainly spark competition among other biopharma companies. A combination of a drug that helps with a tinnitus spike and another that repairs synapses, hair cells, stereocilia, or whatever (say after a new noise exposure) would be on every...

If you end up in an emergency room with severe COVID-19, surrounded by a surgical team trying to keep your lungs open (God forbid), they will be completely focused on keeping you alive and breathing. They are not going to ask whether you have a history of auditory problems. They are on the front...

https://en.wikipedia.org/wiki/Eleanor_Maguire The brain scientist linked above conducted a comparative study on the brains of London taxi drivers and other groups, such as bus drivers. The study revealed that taxi drivers, who had to memorize not only street names and locations but also how...

That really is something the guys and gals in white coats need to figure out. I recall one research group mentioning that their drug had difficulty accessing the lower frequencies of the cochlea. Kind of fundamental, don’t you think? It’s like saying, "We have the wonder drug, but we can’t...

It certainly raises questions. For instance, in my case, I’ve had a squint since childhood. The operation to fix it wasn’t 100% successful — it’s mostly cosmetic — but I wrestle with face blindness (prosopagnosia). Until now, I had more or less assumed that noise damage caused my tinnitus, or...

Tinnitus since December 2023? Hang in there. There’s a good chance you’re over the worst of it by now.

@Frédéric, I have to say that I am bowled over by your depth of scholarship. To be able to plow through all these scientific papers and understand them, especially when English is not your native language, is amazing. Hazel, Marcu! Put that man on the payroll or give him a promotion. In trying...

Human brain samples contain an entire spoon’s worth of nanoplastics, study says I had originally intended to post this under the heading of humor (brain plasticity, habituation, and all that). It’s something for everyone to be aware of and to keep up with as times change and new research...

Is tinnitus research still in the poorhouse? I heard that Trump wants to cut medical research as well, though what he says tends to be volatile and temporary.

It seems that hearing research and tinnitus research are developing on a wide front, to borrow a phrase from military technology. The Bionics Institute focuses on finding an objective way to detect and measure the volume of tinnitus, which could accelerate the pace of research and clinical...