Separate names with a comma.
Trobalt (retigabine) is a very different kind of dope :p Just to be clear Retigabine ≠AUT00063 by any mean, they happen to act in the same area...
Very unlikely, I can't think of any physiological reason for this to happen, there is no more reason for this than a reason for the drug to grow a...
Haha you got me :) :p
Many people would give anything for having at least a rat model for a cure for cancer, ALS, or HIV... If we are not positive, who can be ? The...
In a nutshell I have a background in applied economics (lol), I drifted to applied maths and computer science, I was more specialised in...
Shit you got me !!! Well they should pay me for promoting their dope :p
Sorry to interfer here, but it has nothing to do with partial seizure... Most anti convulsant are sodium blockers, meaning that when you block...
Kv3.1 was heavily documented as the main channel for T. considering the number of papers confirming it, I doubt Kv7 is a winner. As I explained...
A lot ! Scrabbles (mobile & fb), the sims social, gangstar rio, ganstar vegas, asphalt 7 & 8, Minion Rush: Despicable Me, Rival Knights, Candy...
Yes, ototoxicity can be caused by noise, drugs or stress. EDIT: basically most of T. should be tackle (theorically) by AUT00063 providing it...
@Christian_B first it's a bit out of my area of expertise, I am quite confortable with the brain, but I did not work much on any other area of the...
@cdog I like you enthousiasm and motivation, but you don't know when to stop, do you lol? Seriously even with a lot of efforts I don't understand...
No I called the theories I read above "crazy" because they are as crazy as not suported by scientific evidence. Yes the mechanisms above were...
Wow, I have been in this thread for a few days and it's like war here. *__* I am really busy at the moment but I have seen so much misinformation...
Hey guys, I am kind of off at the moment as I have a lot of work, I see a few discussion around topics that I already covered, maybe it can help...
I am more this kind of detective :p @LondonGirl [ATTACH]
It is linked to the hair cell, but what I am saying is that sometimes they die in big number and lead to a hearing loss, but not enough glutamate...
The way I see it the problem is not the death of hair cells, some people experience it and just have hearing loss. The problem is the chain...
I just mean I can share with him the mail exchange in case some people doubt of the origin of the information. ;)
I never though about that actually, it's quite an idea man, I will do some research if from the action potential you can deduce how the signal is...
Ok guys, I have an exclusive information, I am discussing with people working on the AM-101 trial (I won't disclose their names, but if need be I...
Go back in the thread, I extensively explain why :p
We discussed the fast track earlier or in another topic, but it's not black or white. I agree that we may not have a fast track like for a cancer...
Engurish good in me, takke me pleese !
Hey Freddie, Yeah the drug is expected to work no matter the time frame, it may just take longer for older T., but it will work too. They want...
The article you mentionned is anterior to hamann/page findings as said by @rtwombly Dude the answer to the glutamate thing is in the first quote,...
Very similar to the pricing above in the canadian pharmacy.
Do you have a link, I am curious to see what it looks like.
My mother is a Professor in Dominican Republic, so she looked up for me, she told me there is a lot of fake drug coming from india there. I doubt...
Correct you can have T. without hearing loss, and hearing loss without T. :)
I found Potiga in Dominican republic but I don't trust them and I don't want to risk to take some crap. I would avoid Mexico if I were you.
@Zimichael , thanks a lot for the message, I ready to start our bromance anytime, just let me know a few weeks in advance so I can divorce too....
Hey! Thanks for the feedbacks I really appreciate. @undecided haha don't shower yourself with trobalt. I have simplified things an awful lot...
Haha I know the feeling, what do you play man ?
Hi @cdog , Thanks for your comment, it's pretty late here in montreal, so I'll be short :) (EDIT: I wanted to be short, but I could not resist...
I stop playing the way I did, but I kept playing for myself, not as much as I would like, but just enough not to forget how much I love playing...
yeah most T. share the potassium channel issue, only blood circulation related T. and some mechanical T. are the exception. Feel free to PM if...
Don't fear too much, the literature is very weak on those glutamate excess mechanisms, or at least what I can find :p If they bothered doing a...
The hair cell death process I mentionned was observed on rat, I assume it might be a bit longer for humans. Now I believe they probably have some...
Hey Mr Hijacker :p I think the sooner the AM-101 is taken, the most effective it will be. Your confusion comes from the fact that you assume that...
Thanks for the comment. I am not sure which post you're making a refence to, but I think I was talking about the cellular level for the hair cell...
Hey guys for the one who just got in the thread, I have explained several times why time has NO impact on the reversability of T. Time only...
Hey iAzara, steroid won't do much for a spike I think, they are useful in the next 24h/48h of a recent increase related to an acoustic trauma. I...
Pretty good definition, this is where we are at the moment but those are not definitive values, this is a first guess for research purpose. I...
The AM-101 is intratympanic because it's a localized glutamate blocker, but if the the AM-102 is targetting potassium channels, there is no reason...
Surprising story guys, I mentionned a while ago that I luckily met the person in charge of the AM-101 in Mtl thanks to my audiologist, and I just...
Yeah, they are fine tuning the drug on rats at the moment :) Then it will go to clinical trials (phase 1 & so on).
Ok guys my 2 cents AM-102 = AUT00063 and will target Kv3.1 potassium channels.
Yeah I agree with ya, you're a smart one, you figured out on your own what decades of T. research just found. Your statement fits perfectly with...
Instructions unclear, dick stuck on ceiling fan. Please advise.
Yeah of course you can :) Also feel free to PM me if you have questions.
Hey, welcome here, Activan is not a cure for T., it just help you sleep, you can stop it if you are not confortable with it. You should consult an...
For Xanax there was a study in the early 90's that was unfortunately not replicated to my knowledge: http://www.ncbi.nlm.nih.gov/pubmed/8343245...
No, unfortunately sound has no known positive effect on potassium channels, (maybe someone has an article ?) Anyway, when you hear a sound for a...
Hey Christian, don't forget the primary effect of this drug (on the paper) is to control spikes, it can potentially reduce the T. but it's not...
This is not a miracle drug by any mean, it's just a somewhat close to what could work.
Yeah I figured it out, plus the drug range of action seems to be too much in the middle & vague. Thanks for the confirmation <3
Most of the big ones are lol It's just they all bet on different stuff related to the Glutamate/Potassium interaction GSK, Pfizer Venture -->...
My T. is also increased when I am under too much stress/ frustration, it's a negative spiral that I try to avoid (too much stress => more T. =>...
Sorry to hear that. :( Do you have antecedent of stress induced T. ?
