Search Results

There's an active thread already on here for rTMS, tACS, tDCS, etc., that's been going since 2012, quoting various studies, people's experiences,...

Did it help at all?

And don't forget the 'other' Auricle (https://auricle.com/) is developing an implant that stimulates the cochlea externally to treat hearing loss...

Maybe @Hazel can reach out for another update from Dr. Shore after some appropriate time period has elapsed since the last one? It might also be...

Exact same for me.

You could well be right, but they are also actively hiring bio-med and other engineers right now. The job descriptions mention developing next-gen...

It will be interesting to see what Neuromod is up to with their Lenire in the meantime - revenue is rolling in, they have electrical, mechanical,...

I highly doubt a commercial plane is 90 dB in the cabin continuously. If that were the case, all passengers would suffer hearing damage on long...

No music for me, but I watch movies w/ subtitles. The noise from either will spike my tinnitus, but it's somewhat of a "damned if you do, damned...

I have very reactive tinnitus that will spike from the background noise and, after serious initial concerns, have now completed many domestic and...

While good to see, it's incredibly frustrating that none of them have direct interest in targeting tinnitus - they must figure there's no money in it.

Do please report back on how you do with the Gabapentin - thanks!

My thinking on this is that if the tinnitus level can be significantly reduced through this or whatever method, then the reactivity aspect should...

Did you find an online source that it can be ordered from?

But hasn't Tzounopoulos concluded that Kv7.2 and Kv7.3 were the specific ones to go after? One concern I have with his work though is that it was...

Agreed - not only do they need to bring the product to market, they now need to displace Lenire from a strong install base on top of that.

It's been said before, but I'll say it again - the most expedient and lowest risk approach to take, IMHO, would be to simply license the IP to...

Even if it still has a ways to go (!), this is an exciting update. The technology could be a genuine gamechanger and, frankly, a treatment I'd...

I just put a few dabs on the earplug. It doesn't need much, and no need to put it in your ear. However, as @kingsfan says above, it does leave...

I was able to improve the sealing of my custom earplugs with this product. It's expensive for a tiny tube, but did reduce the occlusion effect a...

Regarding the above pipeline for three tinnitus drugs, it's interesting to note that with their GW-TT2 candidate they talk about repurposing...

Some updates on their tinnitus related product pipeline: https://www.gatewaybiotechnology.com/services/

I've been in touch with Dr. Cheung on and off about this. His method is invasive (similar to above). Further trials were on hold due to COVID-19,...

Nice little test on this website that will demonstrate what 6 dB increments in volume sound like - scroll down the page and click on the log level...

Got it - thanks.

There's a startup looking to develop just that (coincidentally sharing the same name with Susan Shore's enterprise): Website: Auricle...

in the end, it all boils down to money - bringing the product from prototype stage to something that can be manufactured reliably in volume, FDA...

Probably worth keeping an eye on this (or other similar venture funding focused sites) for funding status, etc (last funding round was $350K in...

The other big unknown is Auricle, the company. No mention of funding on any of the Angel investor databases, the only known employee is the CEO...

In the future, maybe you won't need to trade off - this newly formed startup are working on an implant that stimulates the outside of the cochlea...

It'll be very interesting to see how this develops. For example, if the Mayo Clinic trial is successful, is it something they may be allowed to...

Keep an eye also on Biohaven - BHV7000/7010. They are moving aggressively in this space with an expedited trial schedule, a product they claim is...

From their latest investor deck in January - moving quickly: [ATTACH]

I took Enbrel (Etanercept) for 10 years and first developed tinnitus (noise induced) while on it. I came off Enbrel in 2018 due to being in full...

This pretty much sums it up! I'm just happy that it's now 2023 and we're starting to have some options to look forward to. After multiple...

Couldn't agree more - be very careful. Mine was stable/non-somatic/unilateral until I had an accidental noise exposure that worsened my condition...

The research seems to point to KCNQ2/3 potassium channels as the primary mechanism. I haven't personally seen much on the GABA aspect but you have...

I definitely would not say that - their latest presentation states: "Broad Potential in Adjacent Indications: Warrants further evaluation in BPD,...

No disagreement with the research and clinical trials that support this (Shore, Tzounopoulos, Trobalt, etc), but the reason we're all also...

Tinnitus (TFI) is on the secondary outcome measures list for the FX-322 read-out due in Q1. If we see any benefit reported at that time, I think...

Did you use the noise generating features of the Oticon's or was it simply the amplification of the lost frequencies that helped?

Great to hear - thanks!

I'm not concerned per se, but your observation kind of supports my point - it looks like a one-person organization with a registered company name...

Great to see it moving forward - I hope Auricle are capable of building what's needed to bring it to market in a timely fashion. FDA approval and...

Understood re Lenire - I wasn't talking about adjusting to the tinnitus frequency, only amplitude - they do boost the signal at those frequencies...

Same issue here with custom musician earplugs. What helps, although still not perfect, is using a special gel/lubricant that a) makes them easier...

Michael - apologies for not responding sooner. Thanks for your detailed rely - this is helpful. Paul

Lenire's approach is similar to how hearing aids are customized for an individual's audiogram - they boost the signal where you have a dip to...

Michael, I wear earplugs when driving or when on a plane and my tinnitus still spikes, and usually comes down afterwards. Without earplugs, it...

Don't rule it out - I saw a mention recently (I think somewhere on this forum) of data showing that a cochlear implant in one ear reduced tinnitus...

Since she said FDA approval is being applied for, you would think this indicates that she must have some reasonable level of confidence in the...

I'd hope that your hearing simply needs to be good enough to hear the sound at the appropriate level - Lenire has a limit of -80 dB at higher...

Thanks a lot - very interested to see how it goes. I'll probably contact them myself directly for more information too. FYI, I'm near Harrisburg...

Hi, @ErikaS. I'm in PA also - where is the clinic you're referring to? Do they claim any worthwhile improvements? Thanks!

Having gone through the evaluation process for participation in December last year (and failing to meet the criteria), I can say it was extremely...

@Hazel, this is a great discussion that I've listened to more than once. I wonder if Dr. Tzounopoulos would be willing to provide an update on...

Sorry, I don't want to post my personal prescription, but the details are on both the clinical study webpage and in even more detail on the patent...

Travis, Oxytocin is worth a try if you can get your hands on it - but could be hit or miss regarding efficacy. There are quite a few compounding...

I wonder do they have some anecdotal evidence of Enbrel providing a benefit - Enbrel is widely used by people with chronic rheumatoid arthritis...

It'll be very interesting to see if there's any difference between the <6 month and 6-12 month cohorts when results come out shortly. Since us...