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If you're going to do Cerebrolysin, you should add in Vinpocetine, Pentoxifylline and Piracetam to it too. Here is a patent from Russia where...
Someone should tell Dr. Shim to look into intratympanic injections of 7,8-DHF. It restores IHC synapses and increases neurite outgrowth and is...
I've been real busy recently but I've pivoted slightly in my approach. I have the Zoledronate ready to go but I've actually found a biotech...
It's actually very easy. AllDayChemist or IndiaMART. No prescription required.
It depends. If your tinnitus is from cochlear synaptopathy and the Bisphosphonates regenerate the IHC afferent synapses then it'll affect your...
Will report back here soon, it has almost arrived at my place. I've read the study you're referring to . Here is another study using...
Yes you can. I am going to try Zoledronic acid soon. Going to do 0.5 mg IV infusion. i believe it'll work for my cochlear synaptopathy. Worth a...
I'll be doing 2 months of Oxytocin therapy soon. Will post results once I'm done with my experiences.
Fair enough. I actually ordered the Cerebrolysin for reason other than tinnitus (ADHD) but have seen others say it could help with tinnitus. I'll...
I've been doing some research too and have found out that the compound Mannitol increases absorption of drugs through the blood-labyrinth barrier...
Haha sadly you can only administer it via intramuscular injection which turns people off. It's reported to increase BDNF up to 300%. It also...
The best drug for increasing BDNF is Cerebroslyin. A Peptide noortropic used for healing traumatic brain Injury.
I've had multiple audiograms done and the specialist said they were fine with no damage at all. The thing is I struggle in almost every social...
I actually have higher hopes for Otonomy's OTO-413 than Frequency Therapeutics' FX-322 to be honest. Otonomy are behind Frequency Therapeutics but...
Please let that be true. If they are able to do the pivotal phase without redoing Phase 2, then that's a godsend and saves alot of time.
Do you reckon David Luchinno, Robert Langer and the rest of the team are hurting right now and don't know what to do? Or do you think they know...
I still don't understand how WR scores can increase in all groups but it "didn't work". Does anyone know if they have to do Phase 1/2 again to...
So I bet you they found this out by people who didn't have that bad of hearing anyway that faked their WR scores to moderate/bad and then they...
Only 10 more possible days for the 90 day data to be read out. Cmon already, Frequency Therapeutics.
Tomorrow right?
In that case @Diesel, I will just assume it's going to be on the 26th of March now. 17 days ain't that long, 2 and a bit weeks. I am quite excited...
Interesting. Won't they announce the date when they are going to read out the 90 day data? I don't see why they would keep the date a secret lol.
28 days or less now. Yes I am counting.
Happy readout month.
Very annoying news that Otonomy will take even longer now...
I reckon it'll be around $1,000 per week of treatment, split 50/50 between the drug and ENT. The drug is cheap to make but ENTs will definitely...
It's CHIR99021. Wikipedia mentioned Frequency Therapeutics on this page in the past but it seems it has been edited.
Ah I see. I was just going off what Carl LeBel said on the Tinnitus Talk Podcast. He pretty much said Frequency Therapeutics would be doing Phase...
Frequency Therapeutics are certain on doing the pivotal trial though. Would they even distribute it and sell it if it was approved early?
Exciting but at the same time sort of a reality check for time frames. Pivotal trial in 2022 - Could they start late 2021 though and have it...
My tinnitus is definitely hearing loss related. I fell asleep with headphones on loud for 13 hours and woke up with tinnitus and cochlear...
I cannot wait to feel the cold steel hit my cochlea! Hurry the F up and approve FX-322 and OTO-413!
I wonder what happens to the dead hair cells in the cochlea once FX-322 is administered? Do the new hair cells replace them or are the dead hair...
Good to hear some positive anecdotal evidence but this just makes me more keen for March and May 2021. We still don't know the doses they are...
So can we now expect to have some results available in March 2021? That is late Q1.
Frequency Therapeutics are really going hard. Legends.
Just my opinion but I reckon they will skip phase 2b and go to phase 3. The countdown to April/May 2021 is on.
For sure that's relieving to hear. If they do a trial in Australia I will sign up for it 100% and I'll do a review of it and post it up here if I...
Do you have evidence that a portion of the regrown hair cells aren't functional or is your debate based on the fact that they didn't provide the...
They are expecting to release their phase 1/2 results in the next 3 months. If their results are good, which it seems like they will be, then...
Any articles I can read about this? That's pretty big if you think they could beat Frequency Therapeutics. When I check Otonomy's website, it...
For sure that all does make sense. As for treatment availability it seems like hair cell regeneration will be available first before synapse...
It would annoy me healing tinnitus and not my hearing loss. Although silence would be good, I want to be able to communicate properly without...
Studies are leaning towards people getting cochlear synaptopathy/synapse damage before they actually lose the inner hair cells. So my question is...
So SPI-1005 is just an otoprotective drug after noise exposure?
A good question I reckon is if you have hearing loss that is from both cochlear synaptopathy and the loss of inner hair cells, which order of drug...
Carl LeBel said the phase 3 can take anywhere from 1-3 years. So worst case would be 2024. Praying that isn't the case and the results are good...
Hough Ear Institute seem to be going much slower than Frequency Therapeutics.
@all to gain All they could do is talk shit on FX-322 and say it doesn't work and people don't get benefits from it. Once the cat's out of the...
@aot I am 25 and suffering pretty bad. I am over not being able to go to bars and restaurants and people mumbling all the time. It will be a...
It probably would come out in 2026-2027 without Fast Track and 2023-2024 with Fast Track.
That's really good news. By June next year we should know a lot more. It's already been fast tracked and there is positive results coming out from...
I have been talking to them for a couple weeks. I have sourced peptides from similar biotech companies before for peptides like BPC-157 and it was...
I have found sources for NPH-07 online. All the info you need is on Hough Ear Institute patents which I found while researching. In another study...
Heres where you can buy the drug btw....
i saw your posts on the hough pill. You can buy the drug from chinese biotech companies. it is very expensive tho i have been looking into...
whats up man
Justin, Any chance of your drug being fast tracked like FX-322 was? And how long does fast tracking take off time to hit shelves? Funny, I was...
@MRItechssuck Nothing will happen with just NAC. Adding NAC to NPH-07 (2,4-DSPBN) has high synergy together but you need (2,4-DSPBN) most...
@GBB, that's 2 patents I've read on cochlear synaptopathy that have said it is the cause of tinnitus and repairing synapses heals tinnitus. I...
