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Yeah but from what i've heard the regeneration of outer hair cells is not sufficient enough to completely erase hearing loss. It regenerates only...
Oops, I forgot that spiral ganglion neurons remain active for decades in humans, so the synapse regeneration is possible whatever the date the...
They're talking about improvement when the subject gets injected OTO-413 the day following the noise trauma. So it doesn't work for people who got...
If FX-345 could reach 20-4 kHz, then it's great, but aren't the hair cells responsible for speech frequencies below 1 kHz-2kHz?
I do think everyone experienced improvements. Severe hearing loss sufferers had great response because they have more inner ear hair cell death,...
So FX-345 is exactly the same drug as FX-322 but goes deeper into the cochlea, am I right?
The new drug could be a FX-322 with improved delivery method, so it can reach the cochlea more profoundly or a completely new drug with new...
I think that resolving tinnitus by restoring hearing function or indirectly by OTO-313 won't lead to silence for me. In my case I have spontaneous...
Not sure but I do think that Otonomy gel can hit the cochlea from the apex to the base. I'm saying that because OTO-413 has recently proved...
I think it varies according to the company behind the product. I'm sure that they'll advance first OTO-413 and OTO-313 to get them to the market...
When will the trial results be released?
Why wouldn't FX-322 work on people with mild hearing loss? I don't get it because we know that the hair cell architecture is more intact in this...
If Frequency Therapeutics doesn't work on reformulation and deeper penetration, I don't see how it could be successful.
Absolutely nothing is known about OTO-6XX. They did say that they are going to claim any information when they'll have an update to provide about...
If I take the example of a teacher explaining a lesson to his students in a large auditorium, assuming that all students have excellent hearing,...
I do agree. This is why I'm looking to synaptogenesis drug like OTO-413 or PIPE-505 which have verified proofs. The recent results showed that...
I think this is because the untreated hair cells continued to accumulate continuous damage (if his tinnitus is different than the previous one) or...
Does SPI-1005 treat visual snow caused by previous cochlear damage? I read that it reduces the neuro-inflammation, then it could reduce some of...
This is the reason why I think it is better to get FX-322 first (assuming it comes to the market) and afterwards a synaptogenesis drug (OTO-413 or...
I have noxacusis too, but I definitely think that cochlear synaptogenesis drugs (OTO-413, PIPE-505) will provide more relief than FX-322, basing...
I don't think that's the case for everyone. It's pretty common, especially for young people with good habits to have 0 dB loss or even +5 dB gain...
Considering PIPE-505 regrows some OHCs (unlike OTO-413) and mostly synapses: If PIPE-505 shows results as good as OTO-413 and audiogram...
If OTO-6XX gel is the same as OTO-413 and consequently target a large part of the cochlea, is there any chance for this drug to outperform FX-322?
I have one question: Since the highest concentration of FX-322 is in the high frequencies, does it mean that the more high frequencies we can...
After you receive FX-322 injections at the ENT (if we assume FX-322 is successful in the clinical trials and becomes available to all of us): Can...
Therefore, acoustic otoemissions should be restored? I recently took one knowing about the fact that they are more noticeable in high frequency areas.
Does anyone think that regular head movements and listening to various sounds can help FX-322 to penetrate further in the cochlea and target more...
How can I buy some FREQ stock? I'm from France and can't seem to find any websites to buy from. Thanks.
Do you think FX-322 could not only help hearing, but also vision? I got visual disorders (Visual Snow Syndrome) after getting hearing loss from...
If we receive too many FX-322 injections, can it cause cancer?
If FX-322 comes out in 2023, would it be in the beginning, middle, or at the end of the 2023?
If the hair cells regenerated by FX-322 aren't straight, does it affect hearing or is it just aesthetics?
Does anyone have some advice for getting the maximum benefit from FX-322?
Will FX-322 be available first in the US and then later on in Europe through Astellas? Or will it be available at the same time in the US and EU?
Okay thanks. But if we admit that this information is true, would FX-322 benefit me?
"Spontaneous oscillations of ECCs, producing active mechanisms without prior sound stimulation, could be followed by physiological effects:...
My outer hair cells are probably damaged because of noise. Consequently, I have constantly "swinging hair cells" and it produces tinnitus for me...
