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A news article that came across my feed posted without comment....

Frequency reports raising another $62 million in Series C financing.

This from their press release (my italics): Proceeds from the financing will support the advancement of the Company's clinical candidate, FX-322,...

This conference is for investors. I agree this is a good sign.

I had several intratympanic injections about 5 years ago. ENT said he had only had one patient ever have an issue. I've not experienced any...

This came across my news feed....

Interesting layman's article on recent study. https://www.scientificamerican.com/article/ba-boom-there-goes-your-hearing/

Here is a newspaper article in laymen's language....

Layman's discussion of the study discussed above I believe. http://news.usc.edu/140224/new-study-shows-hope-for-hearing-loss/

Good layman's description of the St. Jude's research. https://cen.acs.org/articles/96/web/2018/03/Small-molecules-shield-mice-against.html

Birds and infant mice regenerate in 4-5 days. I've not seen where frequency gives a time frame for it's treatment.

Good Synopsis of where things are....

Not sure this is the right place for this story, but it's both really interesting and lots of commentary about the current research on the causes...

This is from Hough Institute's 3rd Quarter Newsletter. BABY HAIR CELLS! BY DR. MATTHEW WEST The loss of auditory hair cells in the cochlea is a...

Zug, Switzerland, November 28, 2017 - Auris Medical Holding AG (NASDAQ: EARS), a clinical-stage company dedicated to developing therapeutics that...

I have always been curious why those of us with single sided deafness are not ideal candidates for clinical trials, and yet most of the clinical...

http://newsok.com/article/5560970 This article came across my news feed. Don't see it posted yet, although the trial has been discussed below.

Is there any reason Frequency won't have the same issues recruiting people as the GENVEC trial has had? I was never clear why GENVEC had such...

I use Mucinex regularly without issue.

Does anyone know if the Frequency trials, or any other subsequent trial will have to use the same inclusion/exclusion criteria for participants...

http://www.express.co.uk/news/science/734203/Stem-cells-used-cure-congenital-deafness-birth-scientists-research Link came through in my google...

Norvartis is a partner with Genvec in the CGF166. It's the same trial.

"Ear in a Dish" http://www.insideindianabusiness.com/story/32070439/ear-in-a-dish-to-increase-volume-in-research

The trial has been paused for safety reasons. This is in an SEC filing by Genvec. No other details were provided.

What does this imply about the ongoing cgf-166 trial?

The niece of one of the patients has updated her blog about the clinical trial. He provides an interesting description of what is going on in his...

It's been said before, but all we need is money and luck.

Any idea what the science behind this is?

Most recent update from one of he trial participants: Uncle Jeff recently went back to Kansas this week for what he calls “lab rat session 4.”...

Nucleo, Can you explain this in a little more detail?

I thought this was an article about growing an actual ear when it came across my feed, but it's about growing inner ear hair cells in a dish....

This may be it. https://clinicaltrials.gov/ct2/show/NCT02038972?term=hearing+loss+stem+cells&rank=1

Good synopsis of the current status of things. http://www.the-scientist.com/?articles.view/articleNo/43819/title/Hearing-Help/

Can you explain that? I've read that elsewhere.

Interesting study. This is the first instance I'm aware of where scientists have been able to actually watch the growth of these type of cells....

I've not seen this discussed, but I imagine that if hearing is restored, it would take the hearing part of the brain some time to wake back up, so...

I would love to hear comments from our science smart posters about the applicability of this kind of therapy for adults with noise or disease...

An interview with Rob Gerk 3 months after treatment. Essentially not much change from first interview a few weeks after surgery....

Some comments from lead researcher. Would love to hear people's thoughts about this, particularly FDA testing....

What about this? https://clinicaltrials.gov/ct2/show/NCT02038972

I tweeted Uncle Jeff's niece after the surgery who said that she would post more info and a video if allowed. Genvec's CEO on the last earnings...

I saw this a couple of weeks ago. http://www.hindawi.com/journals/bmri/2015/154272/

#jeffinkc twitter hashtag indicates patient received a dosing today. I've asked if she knows what the dosage amount was since she previously...

See latest update on testing. Raises several interesting questions about the testing....

More info on the testing regime: https://sites.google.com/site/vestibularneuroengineering/Home/cgf166trial

I recall the CEO stating, well before the trial at one of these investor conferences that were available online, that they did not expect the...

According to the GENVEC earnings call, this will be the 40 ul. They are also doing these sequentially, but I don't know the timing. I think...

I was tweeting with the person who has been posting the #jeffinkc updates on twitter and on her blog. Jeff will be getting the surgery on May 13...

Take this for what it's worth, but it looks like they have dosed all three in the first "safety" cohort. http://2030something.me/jeffinkc/

This is a transcription of the earnings call for Genvec. I've tried to pull out those potions relevant to CGF166. Joe Pantginis - Roth Capital...

I guess I should have read the blog before posting! It sounds like they have dosed at least three people. The clinical trial is set up to test...

http://2030something.me/2015/02/06/jeffs-in-kc-day-1-at-he-novartis-hearing-loss-clinical-trial-using-the-drug-cgf166/ Looks like they are dosing...

GAITHERSBURG, Md., Feb. 2, 2015 /PRNewswire/ -- GenVec, Inc. (GNVC) today announced that its President and CEO, Douglas J. Swirsky, will present a...

Not much news, but another mention of cgf-166....

These are all the slides from the Genvec presentation on cgf-166.

Sorry . . . Tom, Can you clarify the above statement?

But they also stated, that this therapy also hided in the labs of Novartis and that they might did improve something. If there won't no harm to...

My recollection is the time range for improvement in the animal model was 3-5 weeks. The clinical trial info is here:...

Genvec, the company that owns the patent on cgf-166, is up 75% in the last three days of trading. That makes me optimistic that someone knows this...

They used monkeys to determine the location of the injection. I don't believe monkeys received the drug.