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I think most who consider tinnitus to be disconnected from hearing loss use an audiogram and think "I have no hearing loss, but I have tinnitus....

Calcium ion channels are also involved in the accrue phase. If I remember correctly release of calcium is one of the steps in the cascade of...

Anti-inflammatory makes me believe it belongs to the same category as AM-101/Keyzilen, meaning it's geared towards treating tinnitus at the...

If you listen to the Tinnitus Talk Podcast about Frequency Therapeutics with their representative Carl LeBel, he speaks about this. At Frequency...

Agreed. I don't use the dryers either. If there are no paper towels I just give my hands a quick shake after washing and then just let them air...

We don't know. We can only speculate. But I believe I've read somewhere that someone from Frequency Therapeutics said that they had indications...

What about long term use? In the trials they only did the treatment for a number of weeks. But we still don't know what would happen if someone...

True but still important. To be honest there is nothing in the area of treatment that I could read about in his research. So talking about...

I've never advocated TRT. I have made my stance on TRT vocal several times on this forum. I find it to be a complete waste of time and money.

This is simply not true. Hearing usually deteriorates over time. Listening to headphones at higher volumes for hours over a longer period will...

Listening to music using headphones can get you up over 100 dB, depending on headphones and HiFi equipment can definitely get you over 100 dB,...

Not JUST 2. At least 2. Multiple implies more than 1, which is AT LEAST 2. But there could be more.

Well, the US were leading in the field at the time so cutting the funding killed and/or slowed down progress. Which set the field back a number of...

You can read it in a press release note on Frequancy Therapeutics home page....

Well, maybe. More than one person had some improvement in hearing. But we don't know if that is due to new cells, new cells connecting to existing...

For me it's been ups and downs. When I got it back in 2006 it took me about 2-3 years to habituate. After those first couple of years I rarely...

It's possible that regrown cells don't attach to a nerve and if they do regrown cells might perform worse than cells you're born with. Yes birds...

As I said don't confuse machine learning with AI. And also, as we can learn from tinnitus research, they always over sell the idea in articles.

I never said people don't suffer. Absence of suffering isn't the same thing as moving on. I suffer but I still try living my life.

I don't have the citations from studies or so but if you think about it logically you will come to the conclusion that most people do learn to...

Reason: George W. Bush! George W. Bush banned federal funding for stem cell research which set the field back many, many years.

Potentially, better. But all we can do now is speculate. We don't even know if the drug works at all as it's intended. And even if it does we...

Because nearly 100% of all people who have tinnitus have hearing loss. And even those who "don't", like me, probably do. It's just not measurable...

Frequency Therapeutics FX-322 University of Minnesota device

Probably yes. It's one thing saying you would in a theoretical scenario like this and another actually doing it when presented with the option in...

Well, the chances are that most of those who are said to not have hearing loss indeed do have some hearing loss. The problem is that hearing...

https://en.wikipedia.org/wiki/AlphaZero That might be the end goal perhaps?

No, not any game. Just three board games (Chess, Go and Shogi).

Sure. But will we do all that by 2030? It might sound far away but 10 years is not that awful long of time. And saying stuff like "if we solve...

No, the first AGI will probably not be programmed by humans only. It would probably have to be an AI that we create that can improve its own code...

There is no consensus in the matter among AI researchers. Some believe 2030 and some say never. I never said ALL of them said not by 2030. But...

I'm a sci-fi guy too. I have written in several posts here before that I believe that the ultimate solution will not be regenerative medicine but...

And Moore's law has been broken for the past half decade or so. The development of the 7 nm generation of processors has taken more than 2 years...

That's funny since most AI scientists don't believe we will have an AGI for at least another 30-40 years, if ever! There actually are AI...

I firmly believe that implants will be the ultimate cure. Once we've developed an implant to perfectly mimic the human inner ear that is. Just...

Stage 1 I think. But not started yet. He just got the money for it.

The funding for tinnitus is low as it is. We aren't getting even a fraction of what cancer research is for example. So to make it short, we have a...

Actually the Trobalt redesigned is being developed by Prof. Tzounopoulos att University of Pittsburgh. He recently secured funding from the US...

The point is the you need it delivered at the precise location in your cochlea. Even if you manage to keep most of it in your middle ear you...

They may be for now. But you might not need as much of a medicine if it's delivered at the precise location where it's needed. When you inject a...

I'd take 40 injections over 40 years of tinnitus any time!

Great to get an update. I do have a follow up question though which I'm hoping you might have an answer to or at least a hum, but I get it if you...

I'm not sure that a meeting once a month between all tinnitus researchers is either useful or practical. First it would be extremely difficult to...

There is no way of measuring long term side effects without it taking a very long time. I think we will just have to be happy when any treatment...

There is a lot of research going towards pain medication and antibiotics. We've had the Aspirin and Penicilin for almost 100 years. FX-322 hasn't...

Yeah, this is absolutely right. The patenting process is a joke. There is a guy in Australia that managed to write a patent application and get it...

We already have people that have had complete resolution of their tinnitus from various reasons ranging all from cochlear implants to having a...

I was tinnitus free for the first 22 years of my life. Why hasn't that been permanently entrenched in my brain?

If damage to the inner ear drives brain plasticity to produce tinnitus. Wouldn't repairing the damage drive the same brain plasticity mechanism to...

Oh and by the way. Genetically modified E-coli is pretty standard for producing certain organic compounds. Genetically modified yeast is another....

Both refer to the same study and it is deeply flawed. Just for one, all rats died from natural causes. Meaning they were all old when they died....

No, it didn't. It's been a lot of trash talking and rumors about aspartame through the years, hence the rigorous testing of it. But it's not...

Well, Aspartame is a dipeptide (it consists of two amino acids), witch technically makes it a protein. It was actually approved by the FDA in 1981...

What do you mean?

Because it's not a drug per se. It's a naturally occurring flavone that can be found in leaves of certain trees. And extracts from plants are...

The problem is that there is a protocol that needs to be followed. First you need to show that your drug is safe on healthy subjects before you...

"To follow both these aspects we select donor umbilical cord tissue-derived mesenchymal stem cells (MSCs)." Source:...

There is a lot of information in the treatments section in the threads about stem cells. There is also some research papers on the subject. Very...

Well, pretty much everything you read everyday is "allegedly". All the research papers shared on this forum can also be seen as "allegedly" since...

There are members on this forum that have hade successful stem cell treatments. The first one did it 5 years ago.