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Someone randomly liked a post from this old thread, so, I'm just going to give an update saying that I stopped around COVID-19 after making a...
Very sorry you haven't had recovery yet. Very strange for some people in studies of growth factors and stem cells after a significant amount of...
Also, based on what I read a few months ago, growth factors also encourage differentiation and proliferation of stem cells, so it sounds to me...
Unfortunately, I had a conversation with Dr. Minbo Shim, and he said that he tried standalone growth factors, but they didn't work well enough....
A lot of people forget that 70% of the world aren't altruistic in nature.
Got sick on Thursday and now my left ear is bothering me more.
Yes, this is a weird situation where much of the anecdotal reports on growth factors on Tinnitus Talk do not match the results of the scientific...
Principle Component Analysis?
His conspiracy theories were a bad influence on my anxiety back then and it really disturbed me how far he was willing to go to slander/insult...
I'm going to find a way to treat this, one way or another. It's not a matter of if, it's a matter of when. Nothing will stop me.
If the exosomes were lab-made, then it sounds like a similar situation with the lab-peptide version of IGF-1, so that may be encouraging for me....
@ErikaS I just read that exosomes are lab grown somewhere. I was strongly considering getting the standalone foreign IGF-1 until I read that such...
Ok now I'm starting to consider stem cells first and then PRP as a follow up. My bank account is going to be so empty until the second quarter of...
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1165-5#:~:text=During%20this%20process%2C%20pluripotent%20stem,to%20the%20desired...
"Stem cells require a mixture of growth factors and nutrients to differentiate and develop. The medium should be changed each day." -(BMC)
I may have reactionary tinnitus. I don't have hyperacusis, but any time there's too much moderate noise I have a weird equilibrium glitch along...
Could it be partial damage or could it be inflammation? If it's the latter, there should be hope for it to repair as long as you give ears a rest....
@GeraldHenders "Stem cells require a mixture of growth factors and nutrients to differentiate and develop. The medium should be changed each day."...
@Ryan Scott There have been studies on both humans and animals, one of which included children. Most of them have focused on SSHL as an...
We are literally in a situation where publications around the world have shown promising efficacy and yet people here haven't had such results....
@GeraldHenders Right. Despite there being plenty of credible studies on efficacy of PRP that showed many people benefiting it and why, those here...
The least costly potential solution to this madness just HAD to have a cancer risk, among other things. Ugh. There's always a downside.
@GeraldHenders PRP is the safest method of growth factors, and carries many of the growth factors that have been studied to work on SSHL etc, but...
@GeraldHenders Growth factors have shown to have efficacy, especially IGF-1, especially through PRP, but it doesn't always work for everybody, and...
If you're seriously considering this, it will come down to an ENT. Show your doctor the published studies on IGF-1 and PRP, discuss the safety...
It's amusing how 7 years ago I was complaining about tinnitus and 10 dB hearing loss, but now I'm complaining about a notch at 20 lol.
@sakrt What do you mean? Why aren't there more SC/PRP clinics doing IT-injections? Probably because it's not skin/muscle/skeleton related....
Ok. So. Standalone IGF-1 IT-injections: Very risky, despite studies of efficacy. ~100 mcg may be all I'm willing to try. Will ask doctors.
Keep hoping, searching, and fighting. An answer will be found. Maybe not today, but someday, and that someday could be here before you know.
It would really help if anyone knew a endocrinologist so that we could have an educated insight for IGF-1 safety.
IGF-1, insulin-like growth factor 1, is a growth hormone that helps regulate the human body's division of cells. It helps us grow when we are...
If I could get $300 PRP injections for what it would require, I could probably find myself doing that in India in the near future. I'm going to...
My lack of time from a few months ago made me believe that BDNF wasn't in PRP, but it apparently is? That's good I guess.
That's good, but that's just half of my issue I'm afraid. I have a hearing loss notch in my left ear that makes focus and conversation very...
It's been acting up since I stopped using LLLT. At my community college, I have a course where I have to assemble motors and another where the air...
Fibroblast Growth Factor, BDNF, and Insulin-like Growth Factor seem to be the most discussed growth factors in stereocilia regeneration.
Fibroblast Growth Factor is another growth factor worth looking into. Unfortunately, there's no peptide version available.
If molecular, stem cell, and growth factor therapies don't work... just... what else would there be left?
Hey, are you using a hearing test app? There's a really good one called Hearing Test Pro on Google Play. It may be on the Apple Store. It actually...
Most of what I've read online of studies on humans have been focused on sudden sensorineural hearing loss, including the PRP (which contain...
I must admit that the more I look into the "peptide" version, the more I am interested in trying to get that from an ENT. If the price is really...
Why does regenerative medicine have to cost so much? Lol
Foreign standalone IGF-1 is a cancer and diabetes risk because it creates an imbalance in the system, as opposed to what is naturally produced in...
Both chromatography and immunoaffinity purification can be used to purify IGF-1 from plasma or serum. However, immunoaffinity purification is...
IGF-1 extracted from PRP that is at least 150 micrograms. There are numerous studies showing that IGF-1 is capable of so much for the cochlea, but...
There are moments like this where I wish I was rich. A potential answer right in front of me but it could cost so much money.
My first contact will be Advanced Rejuvenation in Florida since they still do IT-injections. I will go through every option that's known of.
@scotty03874, after further research, I am back looking at IGF-1 now that I have learned that it can indeed be extracted from PRP. There's so many...
Hey Erika, how are you? From my own research, I have learned that IGF-1 can be extracted from PRP. This would be my preferred option since IGF-1...
This Eureka feeling would be great if I had the money and time to test it out lol.
150 micrograms of standalone IGF-1 can be extracted from PRP. The safest most potent option, but it would cost more.
Well, I am glad we finally have this context. Forums can really be a huge game of telephone. I'm not going to pretend I know anything about this...
To add to that, studies show that stereocilia proliferation include new ribbon synapses... So it's unlikely that a serum that's supposed to turn...
If anyone is willing to help me evaluate the legal feasibility and find places that would be willing to do standalone IGF-1 intratympanic...
Growth factors and molecular therapy still seem like the most popular solution. Perhaps you'd be interested in doing some research on IGF-1. It's...
Have an ENT appointment so I can finally find out why my ear behaves strangely in April. Will also see about plausible damage treatments.
As far as I know, it was repurposed as a dye, much like a lot of things.
I've had ear issues since I was in high school, which started from two really bad ear infections and a firecracker to the ear (my mistake). Not...
I strangely haven't researched exosomes separately. I probably should look into that. My first objective is to see if I can get IGF-1 IT-injected...
Looks like I am getting another ENT visit... After some hopeful diagnosis, I wonder if I can potentially get the treatment I want to try.
