Search results for query: *

  1. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    I think too some people, myself included, find solace in research. It makes me feel informed, which by extension makes me feel empowered. Others - like my mom - find it more anxiety inducing. We both have severe tinnitus but seek refuge in vastly different sources. She even knows about the...
  2. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Sorry guys, this is late inbound but I wanted to post these ever since @FGG sent me Fuad Lechin’s neuro circuitry book. Here are his before and after pics for various conditions that had a large inflammation component, which he treated over various lengths of time. This is to show how damaging...
  3. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    It will be a lot of people’s go-to drug for their first pass on treating their hearing disorders to be sure. I certainly plan to take it as soon as it comes out, as well as always have some on hand for spikes. But I wanted to ease the minds of people by showing that the options for treating...
  4. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    @FGG could answer that better than I can. Hopefully they’ll see this.
  5. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    The main compound of the pill (HPN-07) is a free radical scavenger, and free radicals are heavily implicated in oxidative stress and inflammation. The synaptic regeneration was I believe a secondary and surprising outcome to the initial study on the compound, which was mostly concerned with...
  6. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Quick add-on from me: For inflammation, we also have Otividex (OTO-104) and the Hough Ear Institute Pill. Although I think the Hough Ear Institute Pill is treating cochlear inflammation directly rather than neuro-inflammation like Sound Pharmaceutical's is. And for synapses you’re also looking...
  7. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    @annV comin’ in hot!! Thank you!!
  8. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    No problem, here’s a link to the study. It’s behind a paywall unfortunately, but the abstract gives you the basic gist. https://pubmed.ncbi.nlm.nih.gov/25940200/
  9. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Meniere's is a tad bit different, because it has more to do with excessive endolymph produced by the stria, than structural damage. For many Meniere’s suffers their tinnitus and hearing loss/distortions fluctuate according to whether or not the stria is behaving normally. Over time though you...
  10. HootOwl

    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    Oh wow, this sounds like it could work if your hearing issues are due to underlying cochlear inflammation, and could also tide us over until the Hough pill comes along. My reactive tinnitus/hyperacusis could very well have an inflammatory component so I’ll definitely be keeping a very close eye...