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@Rube Yes, I think it helps. NAC helps too. I'm not sure how long you've had tinnitus. These supplements might be most effective early on. That said, I've taken melatonin nightly and it does help me sleep, and, I believe, helps with my tinnitus the next day. I've found both supplements...

The drug is used to treat addiction, especially to alcohol, like Acamprosate. (The latter was also tested on tinnitus.) Naltrexone helps with addiction by affecting dopamine. And dopamine pathways are implicated in tinnitus. But note Naltrexone helps with tinnitus distress, not volume...