Burden of Rare Variants in Synaptic Genes in Patients with Severe Tinnitus

[buttercake]

Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study

"The aim of this study was to identify genes for severe tinnitus in patients with extreme phenotype."

"This is the first study reporting the association of rare variation in ANK2, TSC2 and, AKAP9 genes with severe tinnitus and supports the involvement of membrane trafficking and cytoskeletal protein binding in the pathophysiology of severe tinnitus."

 

[twa]

Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study

"The aim of this study was to identify genes for severe tinnitus in patients with extreme phenotype."

"This is the first study reporting the association of rare variation in ANK2, TSC2 and, AKAP9 genes with severe tinnitus and supports the involvement of membrane trafficking and cytoskeletal protein binding in the pathophysiology of severe tinnitus."

I guess we had the perfect set of variant genes.