Recent content by Joeseph Stope

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    Characteristic Alterations of Gut Microbiota and Serum Metabolites in Patients with Chronic Tinnitus

    A novel approach? Outside-the-box thinking? Uncovering every last stone? But just wait for the statisticians to sift, sort, and parse it. In my view, since noise damage is clearly and unquestionably the most frequent trigger of tinnitus, maybe tinnitus is the cause of the changes in the gut...
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    New University of Michigan Tinnitus Discovery — Signal Timing

    Duh… I thought the Bionic Lab Institute of Australia, in Adelaide, I think, had already taken care of that. There’s a lengthy thread about it here. Is there some kind of “Chinese wall” between the various researchers or what? FYI...
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    2024 US Presidential Election

    Sometimes the truth comes out. There’s the case of Kim Philby, who trained the fledgling U.S. counter-espionage agency, the CIA, in the 1940s and 1950s. Incredible but true. He spent his golden years not in England but in Moscow, along with McLean from the British Ministry of Defense and Burgess...
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    2024 US Presidential Election

    Most likely, if there were any evidence that Trump had engaged in pedophile activity, it would have surfaced by now. It’s much more plausible that he knew about Epstein’s preferences and chose to turn a blind eye. But knowing someone’s preferences and finding out what they do in private are two...
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    Losing Myself Because of Unbearable Tinnitus

    I’m so sorry to hear that you’re feeling so low. There’s very little I can add, except to say that one year of tinnitus is still too short a time. Many people begin to pull out of the dive during the second year. In my first year, I used to go for long walks by the river, search everywhere I...
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    2024 US Presidential Election

    Not my side of the pond, but usually in “kiss and tell” rumors involving politicians, one side won’t expose the other because their own politicians are doing the same thing. Of course, in modern times, child sex is a big taboo. The Prince Andrew case is revealing. Allegedly, he befriended...
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    Neurosoft Bioelectronics: Implantable Electrodes to Treat Tinnitus

    I’m sorry to find you going through this. I’ve been a long-term sufferer myself since 1992. I got some relief in 1996 from TRT, which helped with the tinnitus but not much with the hyperacusis. In 2016 and 2017, the tinnitus seemed to worsen again, and now it is back to the disturbing level it...
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    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    It’s great to have a dedicated scientist here who is close to the cutting edge and can explain things. It seems the problem you’ve raised could be rephrased as follows: “The scientists need to create or design an ex vivo cochlea organoid that matches or closely resembles the human one.” It...
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    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    Turning to poetry here, and this is on the topic of discovery. I don’t have a degree in English literature, so this is just my interpretation of some lines by Keats that I remember from high school: “…Or like stout Cortez when with eagle eyes He stared at the Pacific and all his men Looked at...
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    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    It will be interesting to follow the research lines of Cilcare with their man-made organoid, as well as the work developed by James Hudspeth (R.I.P.) and the Rockefeller Laboratory of Sensory Neuroscience. https://en.wikipedia.org/wiki/A._James_Hudspeth Researching the same phenomenon from two...
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    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    Organoids? Are these like living organs, then? It seems that if so, they’re working in parallel with the Rockefeller University project, where auditory scientists extracted a small section of a gerbil cochlea and kept it alive in an electronic chamber.
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    New University of Michigan Tinnitus Discovery — Signal Timing

    I’ll second that! It’s so easy to fall into the trap of thinking, “What kind of juice shop is this anyway? I’ve been waiting here for… {insert number of years you’ve had tinnitus} years! What kind of service is this?” The sad truth is that tinnitus, and hearing loss too, are among the orphans...
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    New University of Michigan Tinnitus Discovery — Signal Timing

    Well, I’m the opposite! I have it in my left ear, since 1992 — thirty-three years ago. It’s no longer the awful threat it once was, but the hyperacusis is still a big problem. So I’m waiting for the printout, as listening to TV, a smartphone, or internet speakers will bring on a tinnitus spike...
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    Cilcare's CIL001 Targets Cochlear Synaptopathy — An American/French Collaboration

    First living cochlea outside the body shows how hearing really works Some more euphoria for you all. Why am I bringing this up again? Well, I think those first in line for the euphoria are the scientific community, audiologists and researchers in particular. The breakthrough is bound to...
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    2024 US Presidential Election

    Splendid idea! I can foresee immense savings if, instead of holding a presidential election, they simply flipped a coin. Heads, Trump wins. Tails, the Democratic challenger wins. The United States and the world would be spared all the noise of primaries, backbiting, scams, and all the related...