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Celastrol enhances Atoh1 expression in inner ear stem cells and promotes their differentiation into functional auditory neuronal-like cells. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150060/ In summary, here we demonstrated that Celastrol treatment stimulated expression of the master...

https://www.nature.com/articles/srep24907 In acquired sensorineural hearing loss, such as that produced by noise or aging, there can be massive loss of the synaptic connections between cochlear sensory cells and primary sensory neurons, without loss of the sensory cells themselves. Because the...

Anyone tried this supplement...

I have a question. If there are missing otoacoustic emissions, does it mean hair cells are dead or that there may be problem with f.ex. synapses? Would hair cells give OAE responses with broken connections with nerves?

I found that my good ear which was protected during acoustic trauma can only hear to 10.4 kHz. What can be the reason? I found also very small tinnitus in this ear when my tinnitus from other ear damaged during acoustic trauma went down. Can be this done by valsalva? To 8 kHz nothing changed...

I have lost some of my high frequencies 3 months ago. Can somebody tell that my tinnitus will go away and my hearing get some regeneration. Is it even possible?