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Suicide does not even need to be justified. We all have different limits to what we can cope with and it is something that medical professionals...

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Not all obstacles can be overcome. Not all ailments can be cured. Not all traumas can be healed. Sometimes, death is the most merciful option.

"The one thing I can't understand, I can't grasp my head around, is I feel when you die, there's just nothing; it's like when you're asleep and...

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"Death is not the greatest loss in life. The greatest loss is what dies inside us while we live." — Norman Cousins

Still the same. Worse.

This morning, I woke up with a very loud tinnitus/spike. I have not been doing anything different. I protect my ears when I'm out. I have also...

RIP Brian. I have spoken with Brian once. We shared our struggle. I was/still am suicidal just as much as he was. I have thought about him in...

My tinnitus was mild and stable for 5 years, then got worse from taking meds. My tinnitus gets worse every day from low/normal sounds. I try my...

I have been told by more than one person that my suffering has a deeper meaning, purpose and that something good is simply waiting to emerge from...

I will look in to this. Thank you.

Yes, fortunately. My mother is my greatest supporter, but she doesn't understand what I'm going through. She feels so helpless sometimes. I sure...

My tinnitus was also affected by COVID-19 I got in December. The increase in tinnitus remained after recovery.

My tinnitus and hearing are similar to yours. My tinnitus is beyond catastrophic. It's just chaos in my head/ears. But it's always comforting to...

Otonomy Reports Corporate and Product Pipeline Update Multiple clinical trial readouts for OTO-313 in tinnitus and OTO-413 in hearing loss...

Well, my hyperacusis is present and at times bothersome. But it's not as debilitating as my tinnitus. Even after setbacks, my hyperacusis improves...

I'm also going through the same thing. My baseline increases to most sounds. Every day or week I have to adjust to new levels of tinnitus....

Hi Glynis. How was your experience with Amitriptyline? Doctor prescribed me it but I'm a bit skeptical to take it as I have heard some good and...

It may be the case. But does curing tinnitus mean complete silence? Assuming there will be a cure. I was once told by my doctor that we all have...

I wonder how OTO-313 and RL-81 combined would work for tinnitus? Maybe the combination may completely cure tinnitus? I'm just glad something is...

My tinnitus is at 12/10 at the moment. Just know that I'm with you. I know exactly how you feel.

I took .25 mg Alprazolam occasionally for about 2 months. But since the trauma I'm considering taking it every night or every other night, just...

Are you still on Xanax? I took it once for a couple months and cold tapered it without being aware of how bad things can get. I just recently had...

Thank you. I will consider those. :)

Anybody who can recommend me meds to lessen suicide thoughts/ideation that won't worsen the tinnitus? At the moment I'm not sure what's worse....

You did mention in the one thread that the problem may be linked to the Cochlear Synaptopathy. It makes sense considering we hear tones just fine...

It's frustrating, isn't it? My tinnitus is severe, but I'm feeling very optimistic and hopeful on future treatments. However, I don't feel the...

I hope Otonomy acquires more data from the Phase II study. I would like to know if OTO-313 works for patients with reactive tinnitus or the type...

I can relate. A few months ago, my tinnitus was the "quiet room" type that only bothered me when I sleep. It's been the same for 5 years until...

6 years of tinnitus. Things got worse 5 months ago. Everyday I look for painless ways to take my life but survival instinct kicks in. I also think...

I'm experiencing the same problem. Watching TV and YouTube videos on phone sounds like everything I'm hearing comes from a low quality or broken...

Hi there. I'm also experiencing the exact same thing. Is it something related to hearing loss? I went to get my hearing checked for the first...

What is meant by "Pivotal trial"? Does it mean if all goes well, Phase II may be the final phase (i.e. Phase 3) needed for FDA approval and if so,...

If I'm not mistaken, tests and assessments are usually done for 2 months after exposure to the drug. This time they will be increasing that up to...

I know what you mean. I've been following Otonomy for some time now. I believe the company has a way forward. As far as I know, their OTO-313...

I know how you feel. I'm at that point too. I've been suicidal every day for 4 months. Severe tinnitus associated with migraines and hyperacusis...

Yes. 100%. It's Valerian root and hops. These are good and can be used for both sleep and stress. The cost should be more or less $12. Do you...

I'm taking "A. VOGAL" Natural herb formulation at the moment for sleep. It doesn't do much but it beats making my tinnitus worse than it already is.

2016-2018: Zopiclone 2019: mostly free from meds 2020: Zopiclone (occasionally when I needed them) 2021: Alprazolam (BENZO!! ) for 2-3 months...

My tinnitus is so loud that i can't distinguish between spike and base. I have also developed high frequency hearing loss/reduction from taking...

I am going through a tough time at the moment and I'm crying while writing this. My tinnitus started almost 6 years ago. Everything was fine...

Thank you very much. I appreciate the advice. I'm definitely taking notes. I'll be heading to a pharmacy store today and try those Magnesium...

I almost never consume any alcohol. In fact I haven't had any in two years. I agree. I understand these things take time.

I'm on the same boat. I would love to know how someone copes with this nonsense! Just got my degree a while ago but reluctant to apply for any...

Phase 3, I'm guessing, will probably include patients with bilateral tinnitus and those who have had it for longer than a year. I'm interested to...

My tinnitus was fine for the past 5 years. Then I took a benzo (alprazolam) for the first time in January this year for stress. Doctor gave me...

I have severe tinnitus (reactive) and severe hyperacusis. I've also noticed my hearing is a little dull. I'm not sure If I have hearing loss or if...

I'm new to this this type of tinnitus. I've had tinnitus for 5 years but recently over the past 3 months it started reacting to sounds. I also...

Thank you for the update. I'm rooting for you!

I believe Otonomy will be the "Space X" of the Biopharmaceuticals field. Hopeful times indeed.

Thank you for the reply. I saw some of your posts back in 2019. Have you improved much since?

My tinnitus is also 10/10. I've been going up for the past 3 months. Louder than last month, last week and yesterday. It keeps going up without a...

Can tinnitus go from severe to mild/moderate over time? How do people cope with severe cases? Is it just a matter of time? I've been on and off...

I can relate to this. My tinnitus started reacting two or three months back. It reacts to any sound. I also love playing music and also playing...

I 110% relate to this. I believe it's called "reactive tinnitus". Mine has been going on like this for a couple of months now. High pitch sound...

My tinnitus was mild from onset(2016) till 2020 December. Things started to change January this year when I withdrew from meds i was taking. It...