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Some people say this and others say you need to wear hearing aids for a while for them to work. Would it be possible to set up an online...
All these Lenire studies have one thing in common. That is, they cannot distinguish differences between the results of various arms. If they could...
According to this, the estimated study completion date is 2024-01-30. Not sure what the "estimated study completion date" actually means. I guess...
Last night my wife and I walked to a nearby neighnorhood mulberry tree for a good feed of mulberries (we used a torch as it was late). I woke this...
Does anyone know if Mirtazapine is the type of medication that can be taken ad hoc? Usually I know before going to bed when I am going to have a...
Yes, that's what she is saying. Clinical trial designs can be broadly classified into parallel and cross-over designs. In the parallel design one...
It does seem like there is some science/rationale behind this approach. More information here: [MEDIA] I'm hoping we get some info about the...
Here are the results from the first trial. Seems like Group 2 did quite well in loudness, but not quite as good in TFI (although roughly...
Thanks for that, very helpful. Personally, I think it is quite a reduction. If I set my speakers so that the 0 dB matches my tinnitus loudness...
Here are some observations and queries: 1) The total number of participants who completed the study according to protocol (the "PP" group) was...
Yesterday I worked as an electoral office during the NSW election here in Australia. It's a 1-off day job starting from 7:00 am and ending at...
Not so easy as there are many treatments that "work" according to the scientific studies, but don't seem to work in practice. That's why forums...
We found a clear relationship between perceived loudness and TFI when we looked at the cohort for the Lenire study. But I guess perceived loudness...
The cynic in me suggests that the closer a product gets to commercialisation, the more untethered the claims become...
I think we’ll need the full paper to come out to fully understand this graph. According to the graph, there were also people in the control arm...
Did you do any other tests other than hearing? What about THI or loudness tests?
Maybe the placebo group will get some music? I agree it’s not that simple as some types of treatment may induce a placebo response more than...
Maybe she's used it and it has improved her tinnitus (I understand that the device rarely eliminates tinnitus).
This p-value is for the correlation between the change in TFI and the change in loudness during the active phase. I don't think this is indicative...
Look at the green dots. These represent readings for people without the treatment. There are many more green dots on the left of the vertical...
Yes, on some days I can hardly hear my tinnitus and on others it is quite bad. So, if I started the treatment on a good day, and then had a...
The graphic is interesting (source). [ATTACH] It shows the loudness of the sham group being reduced by about 5 dB (almost 50%) at the end the...
The duration of the treatment was 6 weeks, so I guess this means that after the end of the treatment there was, on average, a 50% reduction in...
Hi Manny, I raised the same issue quite a few pages back. It seems like showing that this issue has been overcome in the trial protocol is...
You are right. There are so many studies out there for treatments which have positive, statisitically significant results, but which are not...
TFI reduction of 10.1 for the control and 17.8 for the treatment. No significant statistical TFI reduction difference between the control and...
Stop beating around the bush and tell us what you really think.
How about a double-blinded sham controlled positive result that is ALSO replicated by at least one set of independent researchers...! Would have...
We’re lucky Penicillin was invented when it was as otherwise we might have been up for several hundreds of thousands for treatment by a wonder...
No control again, however: “After obtaining the consent of the Office for Registration of Medicinal Products of the Republic of Poland, a...
How did the testing go?
The other thing about Seoul is that it has very wide (and busy) roads in the city (apparently to facilitate tank access in the event of a war). To...
Hi Toby. My understanding is rotating the headphones 180 won't work as this will also involve rotating the microphones and you will still hear...
Looking at the graphic in the original post, looks like you need to do it for at least 40 hours to start seeing some effect (the more the better)....
Oops, you are right. And no manufacturer is going to include the swap feature because (almost) no one will have a need for it (and it also could...
Wouldn’t it be easy enough to test this. You can buy headphones or earbuds with “ambient mode”, e.g....
There was an article about this in the mainstream press today (The Daily Telegraph in Sydney). Just a short article saying that 1 in 10 suffer...
Someone should do a study and write a learned paper on “Placebo effects in tinnitus trials”! Seems like they would have plenty of material.
We’ll need to wait for this to be sure it actually works. Let’s hope they can get it done quickly. Sounds promising.
I'm not buying it. As others have said, they could have done all the stats pre-work in advance and just plug in the numbers when they become...
I've thought about this as well. If the treatment was with a pill, you could even do blinding (e.g., someone from the forum sends out a batch of...
I’ve made enquiries, but they’re too expensive. Around AUD $8k I think. Trial period is short, but you can get 3 months I think by paying...
I don't know. It's strange. There must be heaps of $$ to be made if it works. Maybe there is a reulctance because there is no drug which works for...
Well, the article states: Age and tinnitus duration were also associated with poor clinical outcomes because of the likelihood of chronic...
So many trials with positive results. So few available treatments that work…!
This looks like a very interesting treatment and hopefully it's legit! Especially interesting is that the results persist for at least the year...
Exactly. Trials/results without controls are fairly meaningless...
It looks promising to me, and it will be very interesting to see the results later this year. It’s a little strange that the original paper...
Neuromod have stated that 86% of participants who undertook the treatment in their trial saw an improvement. This stat only has meaning if all the...
Well, I've done a natural experiment by losing quite a bit of weight (got a few kilos to go). I'm now 75.9 kg (167 pounds for Americans) and my...
Could very well be due to a placebo effect. It could be that you are anticipating relief from your tinnitus from this new treatment, hence your...
Yes, some go to 12 kHz, but typically these models area at the top of the range, and hence more expensive. For example, Oticon OPN 1 goes to 10...
You can read for yourself here: Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and...
Yes, but the completed trial, the only one we have results for, and the one that we (or at least I) are basing our assessment of the potential...
Most tinnitus is somatic tinnitus I believe. But the fact that this treatment’s potential is based on such a small sample size and that it is one...
I think this was based on their TENT-A1 results: [ATTACH]
I quit a stressful job and my tinnitus went down quite a bit for a few weeks. But it came back after this. I also did a trial retirement for a...
Did your friend use the Oticon More 1, 2 or 3? Oticon 1 is a 10 kHz model, 2 and 3 are 8 kHz models.
This is the type of study I’ve been looking for for a while :). Looks like an average of -15 THI if you lose some weight (say 5%), eat well, and...
I have been working in Canberra recently (about a four hour drive from my place in Sydney). I’ve driven to or from there six times now. On each...
