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Science Magazine Recognizes Frequency Therapeutics’ PCA Regeneration Technology as a Breakthrough in Regenerative Medicine...
Frequency steals Otonomy’s CSO:...
I don't think OAEs measure above 8k, just like standard hearing tests. Mine didn't anyway. Listen to a frequency sweep on low volume on decent...
Three-way Collaboration with the U.S. Army, Harvard University and Frequency Therapeutics to Focus on Progenitor Cell Regeneration in Muscle...
You're thinking of auditory neurons. Synapses connect hair cells and neurons, they necessarily die when hair cells do.
Synapses without hair cells are not possible. They are connecting fibres. If a hair cell goes, its connection to the auditory nerve goes.
My hopeful speculation (based on nothing) is that if these deafferented hair cells are near to missing hair cells, the regeneration process might...
I'm hopeful that restoring input (by regenerating hair cells in the case of FX) will alleviate hyperacusis as well as tinnitus. I think it's very...
I guess that there is not a straightforward answer because it depends on the toxin. Some drugs may destroy just the hair cells, in which case...
As far as I understand it, the dead cells are cleared away/reabsorbed by the body and are no longer present at all, so regenerated hair cells will...
I think this may be a misconception about how hair cell damage causes tinnitus. It's likely that the brain amplifies frequency bands where there...
I guess that's like asking how tinnitus goes away along with hearing loss associated with a high dose of aspirin, or how it goes away after...
4. Aspirin at high doses, which causes temporary moderate hearing loss, also causes temporary tinnitus (and hyperacusis):...
https://www.theguardian.com/science/2017/dec/20/breakthrough-for-genetic-hearing-loss-as-gene-editing-prevents-deafness-in-mice
No new information really but here's a podcast about Frequency: [MEDIA]
Not much in the way of new info but there's a new Bloomberg video segment at the bottom of this page...
Yep, fair enough, I'm just bulletpointing what he said
- They will be releasing a new paper with "data that will continue to capture the imagination of the scientific community" - They hope to have...
“We expect to be in the clinic within the next 12 months” Timeline proceeding as it should :rockingbanana:
Does anyone know if it's possible for stereocilia to be damaged by noise but the cell structures themselves live on, despite this damage? I hope...
I didn't know that. Is there research showing that milder hearing loss is all outer hair cell damage, with all inner hair cells intact?
I am really happy that Phase II is scheduled to follow Phase I so quickly, bodes well. The race is on
Good to see a report like that on Frequency Weirdly worded statement from the voiceover though: "We are born with the exact same number of...
Here's an interesting exchange I recently had with Will McLean on reddit: As I understand it, the gel you are working on is designed to activate...
Excellent. They're the real deal
I'll take it lol
A bit more good news. I got in touch with Will McLean and asked him: The findings that have been published so far involve cochleae removed from...
Well he posted: "I am founding a science company based on my research. I will be a co-founder and the person conducting the experiments" two years...
From Frequency's website: Dr. Robert Langer is an award-winning Institute Professor at MIT. He has written more than 1,350 articles and has over...
Holy moly, look how many honorary degrees and awards Bob Langer has: http://web.mit.edu/langerlab/publications/RSL-CV.pdf
Yep, bit of a worry. I could imagine extra hair cells springing up in various areas causing worse tinnitus/hyperacusis due to distorted...
I can't think that a gel injection to the middle ear would cost thousands. But even if it does, I will never have put together so much money so...
Another question... Don't the supporting cells next to healthy non-damaged hair cells also get activated and generate extra hair cells, and what...
Direct those questions to the hyperacusis support page: https://www.tinnitustalk.com/forums/support.55/
Samir posted a summary of correspondence he had with Dr McLean a couple of pages back. On this point he said: The hair cells they make in a dish...
I'm not sure... it probably can be nerve damage instead of/as well as hair cell damage. Anecdotally I find it a bit coincidental that my...
Thank you. Ok, that makes more sense, so the molecules in whatever gel they make will target existing supporting cells and the resulting hair...
I also have some questions. I think I may be seriously dim on all this but I’m not clear on the following: - Has Langer and Karp’s research...
I’ve been keeping a Word document with every hopeful thing I can find, and Frequency Therapeutics is one of the only developments keeping me going...
I am hoping that treatments repairing hair cells and/or neuronal connections make speedy progress and that these will address our symptoms...
Thank you SilverSpiral and PaulBe, that's really good to know that I'm not the only one! Do you have measurable hearing loss? I guess this...
I'm curious to know whether anyone else experiences tinnitus in the same way as me, as I've yet to see it described. I have noise-induced...
