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Weed no longer causes spiking
I can't directly attribute my 'recovery' to anything except the passage of time. Unfortunately, this is usually the case with hyperacusis, it's...
I should clarify that I'm not cured of hyperacusis by any means. I still experience occasional pain in my ears and some sound distortions (as well...
Yea I'm back to playing bass and want to start learning electric keyboard (the overtones of acoustic are still a bit too harsh). Electronic drums...
Free masons were knocked out of power and now we can proceed with curing every ailment in the body, cyborgs, and spatial/oceanic colonization....
Mindfulness activities; anything that induces a flow state in the brain. Drawing, reading, journaling/writing, quiet music (if you can handle it),...
I thought I'd never be able to use headphones again, and I went through a period of about a year where I didn't once dare put a pair around my...
Recreational tripping on DXM (Robitussin cough syrup) about 10 times, and I now take Zyprexa (mood stabilizer; olanzapine) and Vistriol...
Y'all probably know my story around here. Suffered alone in a room not being able to go outside because of crippling hyperacusis. I'm all good...
Try having both lol.
Well boyos, it's been 10 months with hyperacusis and things aren't looking too good. I've accepted that this is my new life now; no more...
I hope not.
Some pretty mega cope in this thread.
Sometime in Q3, probably June-August.
People settle for a level of despair they can tolerate and call it happiness.
Bro, FX-322 or any regenerative medicine for that matter is not coming out before Ebselen. Accept it.
I seriously doubt FX-322 will be out by 2023, assuming it comes out at all.
8 months in and the distortions are still going strong.
CPU: Ryzen 3600X GPU: GeForce GTX 1660 RAM: Corsair Vengeance RGB Pro 16 GB MOBO: MSI B450 TOMAHAWK Case: Corsair Crystal 460X RGB ATX Mid Tower...
Typical pop science journalism.
B-but the three super responders from Phase 1! (copes harder)
Lawyer up.
This is making me nervous, I'm getting the Pfizer vaccine soon and have tinnitus/hyperacusis.
Damn bro this post kind of freaked me out, not gonna lie. How are you feeling two days later? I'm not sure there's a way to do this without...
I could be wrong but I think CRISPR would only be useful for preventing tinnitus, since our genes have already expressed themselves.
That's a pretty huge assumption. Probably better to hold off on saying those kind of things until the full results Q3. Because people were...
Definitely a call out to Frequency Therapeutics.
What's a realistic timeframe for the first version of SPI-1005 to come out? 2022?
Did this person also have hyperacusis? Surprisingly I haven't found many people online in my scenario. Right now the situation seems kind of...
Because I'm 17. They haven't pushed all the way through yet. The teeth haven't posed any problem as of yet. I don't know the dentist's reasons...
I'm no dentist, but it seems like the problem is that they're growing at a 45 degree angle in the direction of my teeth. I agree that I'd much...
Tbh I wouldn't set your expectations too high for either drug. The odds are against them and you could wind up falling on your face pretty hard.
I have two lower wisdom teeth that are growing in sideways. In about a year I'll need to get them removed from my mouth. The problem is that I...
Based on what? FX-322 was not the smashing hit anyone here or at Frequency Therapeutics thought it was going to be. OTO-414 was delayed by a year...
God damn, going to have to wait another two years for this stuff to come out, and that's assuming it gets FDA approval. Not sure if I can do that....
I don't disagree, but I'm not going to invest my emotional health in a drug that won't be available for another one to two decades.
Ebselen is probably the only clinical stage drug I'm still keeping my eyes on.
Tinnitus Talk before day 90 results: "Multiple injections will surely push the gel deeper into the cochlea." Tinnitus Talk after day 90 results:...
So you literally want an echo chamber around FX-322 because you're too afraid to hear the opposing viewpoint?
What is the mechanism of action for channel blockers possibly ameliorating hyperacusis?
It's called corpspeak.
Are there really zero labs out there selling Ebselen to consumers? I scoured the internet and found some websites but they either looked shady...
I was just explaining why Frequency Therapeutics could not have included that on the interim. 10 dB doesn't seem that great to me and could very...
Wait until the day 210 readout. If it turns out to be effective, then great. If there are no clinically significant improvements, it's safe to say...
Give me all of that if it improves noxacusis.
It was outside the timeframe to be considered clinically significant. They aren't able to count anything outside of the data parameters they set.
Hopefully they take notes on the disastrous FX-322 trial and change their methodology accordingly.
Sad but not surprised
Nothing has to happen, the universe doesn't owe us anything. Our suffering and emotional investment means nothing for any of these drugs.
Looks like Ebselen is the last man standing.
Does anyone else figure this thread will sizzle out and die like the Lenire and Audion Therapeutics ones if day 210 results are just as bad? The...
First stages of grief: shock, denial, bargaining.
On the other hand, I spoke with a guy who had the Silverstein surgery done on one of his ears and is doing great now. He had loudness hyperacusis...
Any morning now we wake up, the results will be out guys.
Imagine someone saying that subtyping is harmful for any other condition.
Probably not.
I'm enjoying the discussions going on here, definitely one of the higher quality Tinnitus Talk threads I've read in a while. I share @Zugzug's...
It doesn't seem like there are any studies on chronic tinnitus, but at least it has reduced or even cured acute tinnitus. Hopefully we can get...
This is not a good look for Otonomy. First the OTO-413 trial delay and now this; my excitement for them is starting to waiver. Sure am glad I...
It sucks but I don't see what this has to do with FX-322, unless you're giving us the warning that most biotechs fail which is already in the back...
