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ZnPy is a very commonly used chemical unfortunately it doesn't cross BBB so the only way to get it to the brain is injection into the spine, not...

Bad news. Can't get my neurologist prescribe RTG he read all the pre-clinical studies I presented to him but he told me he's reluctant to...

I only wish that AUT is successful and won't lose its efficiency after a short while like RTG apparently does

always bear in mind that this is NOT a double blinded placebo controlled trial with rigorous protocol to follow, like the AUT-00063 trial does...

That's a bad news, really bad news I would like to see some trialees who have reported drastic change in T level (some even reported hearing...

muscarinic receptor signaling reduction of PIP2 I have a gut feeling that this may have something to do with the loss of effectiveness of RTG...

@amandine I think the only way we can know the objective loudness of a subjective T is by minimum dB of masking white noise not the TQ stuff which...

He had made it very clear, there is NO double blind placebo controlled study that confirm RTG is effective. and he believed that RTG does not work...

Tinnitus? The medical community doesn't even give a shit They tell you to go for an MRI and if there's no tumor they tell you there's no cure...

For those lab rats on TT we seem to have a continuous supply of novel molecules to play with Brivaracetam (UCB 34714), similar to Keppra but 10...

Regarding the Flupirtine question I did found an article dating from 2006 stating that it is not effective at a dosage of 2*100mg daily against T...

Many A/D and tranquilizers can cause T, yet ironically they are frequently prescribed to T sufferers to help them cope with the situation. It is...

And effect on T when compared with RTG?

To me there's no difference whatsoever between psychological and neurological a psychological T also reflects underlying neuronal hyperactivity is...

I'm afraid someone is taking the risk of going beyond the maximum recommended dosage to see what will happen

Yes, some people even do a electrocochleogram and brainstem auditory evoked potentials I did a 8-16kHz but not electrocochleogram and brainstem...

first go to ENT to check if there is hearing loss if no you may consider trying Potiga?

Congrat to you. If I can have 3 days of silence I can go to grave immediately afterward without any regret

chronicity as a predictor of treatment outcome: single variable linear regression, n=17, slope=-0.333 (95%CI [-2.4, 1.8]), SD=1, P-value=0.744, R2...

Just a random thought, gene therapy might become another line of research direction for T therapy If you get an RNA aptamer which acts similarly...

Would be a good idea if someone can get a fMRI/SPECT/MEG/qEEG scan before and after taking Retigabine, and before/after dosage escalation/reported...

It seems that RTG really has an effect at least when it's in your system and it's probably not placebo Hopefully a derivative molecule with less...

I wish I only had H, at least I can live out my life peacefully in a quiet remote place far from any noise.

RaZaH had good response at low dose too

http://www.cell.com/current-biology/abstract/S0960-9822(14)01037-9 Our network-centrality analysis reveals a widespread decrease in connectivity...

My H preceded the onset of T

Since your case is still acute would you consider trying Retigabine?

@attheedgeofscience Please pm me I'm in contact with a Professor in charge of ENT clinical trials in a local university (he is also my T doctor),...

I just informed my Otoneurologist (top T expert in my country and director of rTMS clinical trial in a local University) about the AUT 00063...

Actually it seems that Maxipost (BMS-204352) had indeed been tested on human subjects, who are stroke patients In healthy humans, single and...

I just discovered that my country's drug office lists Xanax as a more dangerous and more restricted material than Trobalt. Trobalt is classified...

http://www.benzobuddies.org/forum/index.php?topic=96554.950 @Christian78 sorry to hear that, that's also why I hesitate when it comes to...

Another piece of interesting information, a bit old though, don't know if anyone has posted it before Activation of voltage-gated KCNQ/Kv7...

Same situation here. Would definitely like to be a lab rat of AUT 00063 but I don't have hearing loss.

So it only began on Nov. 28 when the first test subject supposedly took his/her first AUT 00063 pill, not October, result too early to tell

Yeah there's still a huge missing link. I also based the speculation of CN involvement on the fact that body posture/gravity significantly affect...

Of course I can't be sure unless I experiment with it myself, but I suppose it's a very dangerous drug which Drs don't normally prescribe to T...

https://www.tinnitustalk.com/threads/retigabine-trobalt-potiga-%E2%80%94-user-experiences.6047/page-2 johno claims his central T induced by Xanax...

Benzo induced T+H probably because Benzo (more specifically Benzo tolerance/withdrawal) caused a down regulation of GABAA receptors and the...

Attention! Someone on a Benzo withdrawal support site experimenting with Potiga also independently reported significant improvement of her...

If the Kv3 potassium channel theory is correct, so it is supposed to work for T without hearing loss too? Then why does the company emphasize...

According to clinicaltrials.gov most rTMS trials require 6+ months after onset, some 1year+, that's why my Dr. refused to let me try the rTMS...

Interesting, it seems that a number of volunteers who are trying Retigabine on this site also report an effect on T spikes.

how much benzo/for how long have you it before you got T? I only took a small amount always 0.004-0.5 for just 2 weeks before I got this thing Is...

it implies that different people have different neuro chemical pathway of T generation/maintenance, therefore future treatment development must be...

I am considering ascending to the top of a mountain during a fierce thunderstorm and getting my brain hacked by a lightning bolt to see whether it...

f..k all psychiatrists and psychiatric drugs, they shattered my life

I, as well as many other people, first suffer from T+H during withdrawal from those filthy f..king psychic drugs (Xanax, AD, tranquilizers). Maybe...

beware of benzo, I got 24/7 T and H during withdrawal from very low dose after only a very short term use.