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Yeah it’ll be interesting to see the long-term data from both COVID-19 infections and vaccination side effects. Right now it seems like a lot of the data is not well compiled. So, I would suspect by this time in 2022, there will be better analysis of the long term issues that need attention. I...

Someone get me up to speed: We think that Ebselen has an anti-inflammatory effect when taken orally that somehow may reduce the symptoms of tinnitus/hyperacusis/noxacusis? It is believed this is the case because subjects with Meniere's Disease saw a reduction in their tinnitus...

If they do... Have them create some kind of "data diary" of their experience. We need to understand to what extent it has helped them, how long it lasts, how fast they notice the effects etc... "It seems to help me" doesn't cut it for me personally.

I’d like to go on the record that trying to secure this stuff on the market and then consume it based on a “back of the napkin” dosage schedule seems like a terrible idea. With that out of the way, I’d highly encourage a scientific, or near-scientific, method be used to determine if this stuff...

We would need to understand which specific support cells are leaking. Not all support cells are progenitor cells. I would think that if there were damaged progenitor support cells that were damaged, FX-322 might not be as effective. Also, Frequency Therapeutics has shown that during the...

So, if I am understanding the description here correctly, it could mean that it might take only 1 OHC being reconnected to the “pool” of Type-2 nerves to begin resolving hyperacusis/noxacusis? Since the nerve seems to only become over-sensitized from the entire “pool” of OHC dying, then...

Can someone point me to any detailed results on the prior clinical trials for SPI-1005? I see on their website, that prior to a COVID-19 treatment, SPI-1005 seemed to be effective in treating Meniere's Disease and Bipolar disorder. Sound Pharmaceuticals cites a statistically significant...

Speaking anecdotally, I tend to think there must be some connection between the trigeminal nerve and the cochlea. In my own experience with sound-related pain. I first experience a very localized ache directly behind my "bad ear" where my cochlea is located. Soon after, I experience the delayed...

All, please excuse my ignorance re: SPI-1005 and Ebselen. I've read a little this morning about how SPI-1005 seems to show significant improvements in Meniere's patients as it relates to tinnitus loudness. Is that what we're expecting to see in those with tinnitus symptoms from another cause...