Can I Take Tizanidine or Does It Make My Tinnitus Worse? Quick Help!

Discussion in 'Support' started by katriina, Mar 9, 2014.

    1. katriina
      Frustrated

      katriina Member

      Location:
      finland
      Tinnitus Since:
      11/2013
      Can I take Tizanidine (Zanaflex) or is it a big mistake?

      Does anybody know? Any opinion would be great!
       
      • Good Question Good Question x 2
    2. Valentin

      Valentin Member

      Location:
      Thailand
      Tinnitus Since:
      17/08/2013
      Take it if you feel the need :)
       
    3. AUTHOR
      AUTHOR
      katriina
      Frustrated

      katriina Member

      Location:
      finland
      Tinnitus Since:
      11/2013
      Thanks for the answer! I would take just one pill so I guess I can take it... Still nervous about this :D
       
      • Like Like x 1
    4. Turgy

      Turgy Member

      Location:
      Germany
      Tinnitus Since:
      2008
      Cause of Tinnitus:
      acoustic trauma
      Does anyone have any experience with Tizanidine - the medication I received from my doctor for muscle tension. Does it affect tinnitus?
       
      • Good Question Good Question x 1
    5. Croaker
      Haunting

      Croaker Member Benefactor

      Tinnitus Since:
      01/2019 T, 04/2020 H
      Cause of Tinnitus:
      Headphones/Car Alarm/Immune Response?
      It’s on the ATA’s list of ototoxic medications, unfortunately.
       
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    6. Turgy

      Turgy Member

      Location:
      Germany
      Tinnitus Since:
      2008
      Cause of Tinnitus:
      acoustic trauma
      I found that. Was thought your thinking?

      How Does Tizanidine Effect Tinnitus?

      Tizanidine hydrochloride is a newly developed muscle relaxant which has proved effective in the treatment of tinnitus, but whose effects on the cochlear nervous system remain poorly understood. The present study attempts to clarify this question through an investigation of tizanidine's effects on the auditory brainstem response (ABR) in guinea pigs.
      A prolongation of the interpeak latencies between waves I-III was observed following the injection of tizanidine. Statistically significant differences between the tizanidine group and a control group were especially evident 3 to 15 minutes following injection. Decreases in the amplitude of wave III were also seen, with statistically significant differences between the tizanidine group and control group being particularly evident 10 to 15 minutes after injection.
      The experiment indicates that tizanidine acts principally upon the central areas of the cochlear nervous system. Comparison of these results with those of other researchers' studies on lidocaine shows that tizanidine's effects on the ABR bear a basic resemblance to those of lidocaine. Hence this agent, like lidocaine, may act to suppress tinnitus principally at the synapses of the central cochlear nervous system.
       
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      • Informative Informative x 1
    7. nebraska_jones
      Conehead

      nebraska_jones Member

      Location:
      Milwaukee, WI
      Tinnitus Since:
      09/2020
      Cause of Tinnitus:
      Unknown
      I just got prescribed Tizanidine today to see if it helps me relax and sleep (which has been difficult with tinnitus and headaches that are most likely TMJ related).

      I will update with my results!
       
      • Helpful Helpful x 1
    8. SaraSuperEars

      SaraSuperEars Member

      Tinnitus Since:
      2001
      Cause of Tinnitus:
      n/a
      I just now came across Tinnitus Talk, and oh boy do I have a lot to see and say, lol.

      But for now, I found myself googling furiously "Zanaflex and ear ringing" because it's just AWFUL. I already have EXTREMELY sensitive hearing - the kind of hearing people think is a blessing but in reality is a loud, overstimulating, exhausting hell.

      I mean now I hear everything but it's muffled, accompanied by the brain numbing shrill squeal. Let my back hurt, for real. I can't do THIS.
       
    9. Pinhead
      Dead

      Pinhead Member

      Location:
      USA
      Tinnitus Since:
      04/2021
      Cause of Tinnitus:
      Unknown
      I wouldn't take that list for much. It's sourced from a guy who has a PhD in Forestry and is not a medical expert. I'm really not sure why that list is so relied upon or why it is supported by the ATA.
       
      • Hug Hug x 1
      • Informative Informative x 1
    10. grate_biff
      In pain

      grate_biff Member Benefactor

      Location:
      Moss, Norway
      Tinnitus Since:
      09/2014
      Cause of Tinnitus:
      Acoustic trauma using headphones
      Would you now?
       
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