Can Trimetazidine (Vastarel) Improve Tinnitus?

Hi guys,

I have had tinnitus for nearly 3 months now and I can honestly say it is driving me crazy. It is a constant, pulsating sound 24/7 in my left ear that does not seem to be getting any better.

A month after it started my ENT doctor prescribed cortisone nasal drops for a month for blocked sinuses, to cut out caffeine and to use some kind of white noise when trying to sleep. 2 months later it hasn't made a difference at all.

I went to another doctor this week who prescribed Vastarel / Trimetazidine.

I just wondered whether any of you have experience with this and what the outcome was.

Thanks in advance.

 

Totally useless unfortunately.

 

According to Wikipedia they give this to tinnitus patients in France.

"Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for tinnitus and dizziness."

Anybody have any experience with this?

Edit:
Unfortunately it also says this "EMA recommends that doctors should no longer prescribe trimetazidine for the treatment of patients with tinnitus, vertigo or disturbances in vision"

 

I confirm, I'm from France and I was prescribed Vastarel when I got my tinnitus. It did not really help unfortunately.

 

Unfortunately all the drugs out there which are supposed to help tinnitus actually it Seems to me that they do nothing for your tinnitus or they make your tinnitus worse.

 

I took it for many years without any positive effect believing stupidly that healing would eventually be triggered. Among side effects there are parkinsonian symptoms and french fda even wanted to discontinue it because there are no proven benefits at all.

 

When you say a "pulsating sound" do you mean you are hearing your heart beat type pulse?

 

Check out
http://otosul.med.br/artigos/medicos/trimetazidina.pdf
It is in Portuguese, but there is a summary that begins at the bottom of page 2.

"Conclusion:
The trimetazidime, an anti-ischemic drug used for many years in Europe as a tinnitus’ treatment alternative, is a safe and successful alternative for neuro-sensorial tinnitus’ treatment."

I searched this forum, and didn't find any results.

Has anyone heard anything about this?!

 

The EMA European Medicines Agency has recommended doctors not to prescribe this for tinnitus. Off-label use of drugs is more common in Europe. Off-label drugs are used for cancer in the USA at end stages.

 

Do we know why? Is that the drug that had permanent visual snow as a common side effect?

 

In France this medication has been officially authorized by the FDA equivalent for the indication "tinnitus of vascular origin". Like the Ginkgo Biloba (Tanakan). This authorization was removed in 2012. Many French people have taken this drug with varying results.

The laboratory that traded the original drug is French (Servier). This laboratory was involved in a judicial scandal related to its lobbying activity with French politicians. This lobbying would have kept ineffective and dangerous drugs on the market without scientific justifications.

 

Hell even the name scares me!!!!!!

 

"Conclusion.
Trimetazidine dihydrochloride therapy was ineffective for relieving chronic tinnitus."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996095/

 

http://www.tinnitusjournal.com/arti...of-tinnitus-an-updated-literature-review.html

90 patients Three months - Results suggest that trimetazidine, betahistine and Ginkgo biloba extract reduce tinnitus symptoms. However, symptomatic relief can be mostly achieved with trimetazidine treatment.

 

I have read that the drug Trimetazidine reduces tinnitus. According to an article, Trimetazidine is more effective than Betahistine.

I bought Trimetazidine today. I already take Betahistine. Would you recommend trying Trimetazidine?

Based on your suggestions, I will immediately start taking it whilst I am still in my acute tinnitus phase.

My sources: ​

• https://atif.sobiad.com/index.jsp?modul=makale-detay&Alan=sosyal&Id=AV497VyBDohDRoFDjGGH
• https://silo.tips/download/tinnitus...betahistin-ve-ginkgo-biloba-ekstresi-etkinlii

 

Why isn't there anyone who has had much experience with this drug?

 

My grandmother has taken Trimetazidine for 20 years and it was the only thing that made her tinnitus better. She takes it twice a day, and if she stos taking it, her tinnitus gets worse again.