Efficacy of Donepezil in Patients with Chronic Tinnitus

Discussion in 'Research News' started by ma7555, Jul 18, 2022.

    1. ma7555
      Doubtful

      ma7555 Member

      Tinnitus Since:
      04/2022
      Cause of Tinnitus:
      Bupropion
      Donepezil is used to treat confusion (dementia) related to Alzheimer's disease. It prevents an enzyme called acetylcholinesterase from breaking down acetylcholine. This means there is a higher concentration of acetylcholine in the brain, which leads to better communication between nerve cells. This may ease some symptoms of Alzheimer's disease for a while.

      It does not have any intel on tinnitus, but there is a clinical trial currently going on in Brazil. I have contacted the researcher and will let you know if I receive any response:

      Efficacy of donepezil in patients with chronic tinnitus

      Some patents are published for it regarding hearing loss and CNS disorders:
      1. Hearing loss
      2. CNS disorders (combined with Memantine)
      Just wanted to share as it seems one of the least known drugs for hearing disorders but who knows, it may help someone.
       
      • Like Like x 4
      • Informative Informative x 2
      • Hug Hug x 1
      ma7555, Jul 18, 2022
      #1
    2. AUTHOR
      AUTHOR
      ma7555
      Doubtful

      ma7555 Member

      Tinnitus Since:
      04/2022
      Cause of Tinnitus:
      Bupropion
      • Informative Informative x 2
      ma7555, Jul 18, 2022
      #2
    3. JPGL
      Frustrated

      JPGL Member Benefactor

      Location:
      Spain
      Tinnitus Since:
      10/2015
      Cause of Tinnitus:
      Hearing loss? Noise? Stress? Unknown
      Has anyone here tried Donepezil?
       
      • Good Question Good Question x 1
      JPGL, Jul 19, 2022
      #3
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