Scientists Discover Method to Potentially Repair Nerve Damage

Discussion in 'Research News' started by PatrickG, Jan 22, 2016.

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    1. PatrickG

      PatrickG Member Benefactor

      Location:
      Stockholm, Sweden
      Tinnitus Since:
      10/2015
      Cause of Tinnitus:
      Punch/kick to the right ear
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    2. Nucleo

      Nucleo Member Benefactor

      Tinnitus Since:
      02/2011
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    3. Nick Pyzik
      Depressed

      Nick Pyzik Member

      Tinnitus Since:
      6/23/15
      Cause of Tinnitus:
      Listening to in-ear headphones & playing in a band
    4. Nick Pyzik
      Depressed

      Nick Pyzik Member

      Tinnitus Since:
      6/23/15
      Cause of Tinnitus:
      Listening to in-ear headphones & playing in a band
      Although it's great to see work being done on sensorineural hearing loss that incorporates damage to the auditory nerve fibers, nt-3 regrowth of neuronal synapses will only work within a 24 hour period. It's been stated by one of the leading researchers in that category whose name is Charles M Liberman.

      Those like myself for example, would not make the cut understandably because of the length of time. Unless of course one continuously keeps feeding their brain neurotrophic factors in hope of keeping those damaged neuronal connections alive. Therefore, research needs to be done on how to reestablish a well working in-going neuronal connection between the inner regions of the brain and to the sensory cells inside the cochlea. Stem cells are basically the only option to allow such a thing.

      My main question that I would still like to understand is when these sensory neurons retract back into the brain after a broken connection takes place from acoustic trauma/exitotoxicity, where exactly do these neurons fall back to? To the thalamus? To the auditory cortex? These neurons play a big role in passing emotional information along to regions of the brain, so what region do they reside in?
       
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    5. Ludwig
      Aggressive

      Ludwig Member

      Tinnitus Since:
      17 february 2016
      Cause of Tinnitus:
      Acoustic trauma
      This question is... for Charles Liberman i think!

      And i write to Charles some days ago. He answer me:

      "Hello Alessandro,

      I am sorry to hear of your troubling condition. You must understand that I am a basic researcher, not a clinical doctor. I don’t see patients, I work on animal models and try to understand the basic biology of the inner ear and how it is damaged by noise and other insults. Yes, we have some new ideas about the possible role of synaptic damage to the cochlear nerve in the generation of tinnitus, and we are working on neurotrophin-based treatments to repair the synaptic damage. The results are encouraging, but we are still some years away from clinical trials.

      I wish you the best of luck in dealing with this debilitating problem.

      M. Charles Liberman, Ph.D.

      Director, Eaton-Peabody Laboratories
      Massachusetts Eye and Ear Infirmary
      243 Charles Street
      Boston, MA 02114

      Tel: 617-573-4233"
       
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