hello I'm new here and io from Portugal and a known Ent doctor here told me to take Sermion 30 twice a day, do anyone know this medicine or have tried? Thanks
Sermion (Nicergoline) — Doctor Prescribed...
- Thread starter BBarbara
- Start date
Member- Jan 1, 2015
- 84
- Tinnitus Since
- 03/2011
- Cause of Tinnitus
- Music, viral? ...
Hi, I'm curious to have more info and opinions about Nicergoline / Sermion.
Any regular users here that could comment?
Any regular users here that could comment?
@davidchampoux
I was prescribed Nicergoline IV therapy and after Sermion 30mg(3x day) for 1month, later reduced to 10mg(3x day) for another month. I'm not sure if it helped, it didn't get worst for sure. Perhaps my hearing loss somewhat stabilized at one level and no significant degradation afterwards, but I also underwent HBO therapy and neck and head massage and some kind of electrical stimulation in the ear canal at the same time so not sure which one really helped or maybe combination of all.
I was prescribed Nicergoline IV therapy and after Sermion 30mg(3x day) for 1month, later reduced to 10mg(3x day) for another month. I'm not sure if it helped, it didn't get worst for sure. Perhaps my hearing loss somewhat stabilized at one level and no significant degradation afterwards, but I also underwent HBO therapy and neck and head massage and some kind of electrical stimulation in the ear canal at the same time so not sure which one really helped or maybe combination of all.
- Jan 1, 2015
- 84
- Tinnitus Since
- 03/2011
- Cause of Tinnitus
- Music, viral? ...
Did you ever try the Sermion? Did it help? You're in Canada, it seems. I suppose it's available there? It isn't available in the US.
A clinical trial of Nicergoline to prevent temporary threshold shift
Background: In Thailand, military personnel attending the annual ring practice are at risk for noise-induced hearing loss (NIHL). Nowadays, hearing protection devices have been approved to prevent NIHL. Furthermore, N-acetyl-cysteine, Vitamin B12 or Magnesium were proved to be effective against temporary threshold shift (TTS). However, limited research regarding the effectiveness of nicergoline on preventing TTS has been reported.
Methods: A randomized controlled trial was conducted. Two hundred twenty-four participants were evaluated for general physical status, hearing threshold levels and blood chemistry. After the inform consent form was explained and signed, the participants were divided into 2 groups. Nicergoline 30 mg twice daily intake was prescribed to the study group (n=119) for 3 weeks. The placebo was prescribed to the control group (n=105) for 3 weeks, as well. At the end of the second week, they had to attend the ring practice. All participants had to wear the silicone ear plugs. In addition, the audiometry was measured within 48 hours after the end of the ring practice. Moreover, aural symptoms (tinnitus and aural fullness) and the side effects of the medication were recorded.
Results: TTS was detected in both groups 14 ears – 10 ears from the control group and 4 ears from the study group (p=0.075). The post-ring practice audiometry showed that the average hearing threshold levels of the study group significantly improved than that of the control group across all frequencies (p<0.05). Moreover, the audiometry from the control group worsened at 250 and 6K Hz (p<0.05). The duration of tinnitus and aural fullness in the study group occurred over a shorter period than that in the control group.
Conclusion: The TTS was found in both groups without statistical significant differences. The effectiveness of nicergoline from the study demonstrated tinnitus reduction after the ring practice. Furthermore, the hearing threshold significantly improved in the study group.
Background: In Thailand, military personnel attending the annual ring practice are at risk for noise-induced hearing loss (NIHL). Nowadays, hearing protection devices have been approved to prevent NIHL. Furthermore, N-acetyl-cysteine, Vitamin B12 or Magnesium were proved to be effective against temporary threshold shift (TTS). However, limited research regarding the effectiveness of nicergoline on preventing TTS has been reported.
Methods: A randomized controlled trial was conducted. Two hundred twenty-four participants were evaluated for general physical status, hearing threshold levels and blood chemistry. After the inform consent form was explained and signed, the participants were divided into 2 groups. Nicergoline 30 mg twice daily intake was prescribed to the study group (n=119) for 3 weeks. The placebo was prescribed to the control group (n=105) for 3 weeks, as well. At the end of the second week, they had to attend the ring practice. All participants had to wear the silicone ear plugs. In addition, the audiometry was measured within 48 hours after the end of the ring practice. Moreover, aural symptoms (tinnitus and aural fullness) and the side effects of the medication were recorded.
Results: TTS was detected in both groups 14 ears – 10 ears from the control group and 4 ears from the study group (p=0.075). The post-ring practice audiometry showed that the average hearing threshold levels of the study group significantly improved than that of the control group across all frequencies (p<0.05). Moreover, the audiometry from the control group worsened at 250 and 6K Hz (p<0.05). The duration of tinnitus and aural fullness in the study group occurred over a shorter period than that in the control group.
Conclusion: The TTS was found in both groups without statistical significant differences. The effectiveness of nicergoline from the study demonstrated tinnitus reduction after the ring practice. Furthermore, the hearing threshold significantly improved in the study group.
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