Steroids: Prednisone / Dexamethasone / Others (Oral and Injections)

Discussion in 'Treatments' started by tweak, Apr 23, 2012.

    1. unknownpleasures
      Tired

      unknownpleasures Member

      Location:
      London UK
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Unknown
      Thanks Chris. Really appreciate your detailed response.

      It's so hard to know what is and what isn't working at any given time as some many factors play a part in tinnitus.

      I think the Prednisolone is making me really depressed and I am having bad thoughts. I just don't feel myself at all at the moment. I have been told to taper down 5mg every two days after this 6 day course of 40 mgs. I really want to quit cold turkey as I am worried sick that the Prednisolone could be making my tinnitus worse or when rational this could be due to my anxiety. I was even thinking of doing a 10 mg reduction each day instead of 5 every two days as I want this out of my system but worried even that could make things worse. If anyone has any further advice that would be great as I am in a very dark place right now.
       
    2. unknownpleasures
      Tired

      unknownpleasures Member

      Location:
      London UK
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Unknown
      I was rushed to the doctor's surgery today by a work colleague. My anxiety went through the roof, I had palpatations, felt generally unwell. The doc said to stop the Prednisolone with no taper as it's such a short course and not the highest dose. I've taken a couple of days off work to rest up and get this stuff off of my system over the weekend.
       
      • Hug Hug x 1
    3. Chriscom

      Chriscom Member Podcast Patron Benefactor

      Location:
      Northern Virginia USA
      Tinnitus Since:
      May 2019
      Cause of Tinnitus:
      Likely infection/ear stress after walking pneumonia
      I'm very sorry to hear you're having a tough time. Speaking only as a fellow-patient, without talking to a doctor I strongly advise against suddenly stopping the prednisolone, which can lead to some serious side effects. At the same time, this drug can absolutely cause depression as well, so you're not imagining that (obviously, you're saying to yourself lol).

      What you should do is contact the doctor or practice that prescribed the drug and let them know what's going on, and they certainly have had patients with this side effect and are your best source for working on how to handle it. I don't know if doing the 10mg reduction would be a better exit--but neither do you. Ask, do not self-prescribe, and I think you may find that even just talking about it will help.

      Depression is nothing to be trifled with, so hang on through this temporary dark moment.
       
      • Like Like x 1
    4. unknownpleasures
      Tired

      unknownpleasures Member

      Location:
      London UK
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Unknown
      Thanks Chris. That's most helpful.

      I was at the doc's today that prescribed as per my earlier post. As it has only been 6 or 7 days on a medium dose the doctor said no taper needed which I did before and was fine apart from some tiredness with.

      I am currently more depressed than I have ever been due to thinking the tinnitus spike I have at the moment won't go now that I'm off the Prednisolone. I'm also panicking in case I do get bad withdrawals.

      Sorry for being so honest above I just don't know what to do.
       
    5. Chriscom

      Chriscom Member Podcast Patron Benefactor

      Location:
      Northern Virginia USA
      Tinnitus Since:
      May 2019
      Cause of Tinnitus:
      Likely infection/ear stress after walking pneumonia
      If you're under the care of a doctor--and it sure sounds you are--you should pay attention to whatever he or she says. Feeling concerned is normal, but if the doctor said no taper is needed, believe it. I know it's very easy for me to say, but try to take it one day at a time. If you--if anyone--contemplates every bad thing that can happen going forward, it gets overwhelming. Focus on the "now."
       
      • Agree Agree x 1
    6. unknownpleasures
      Tired

      unknownpleasures Member

      Location:
      London UK
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Unknown
      Thanks Chris. That's a massive help and very true.

      I slept better last night after a tiny dose of lorazepam and already feel less anxious today. And as you say I have to take this each day and not worry about what might happen. Thanks again mate and hope you are well today.
       
      • Hug Hug x 1
    7. Chriscom

      Chriscom Member Podcast Patron Benefactor

      Location:
      Northern Virginia USA
      Tinnitus Since:
      May 2019
      Cause of Tinnitus:
      Likely infection/ear stress after walking pneumonia
      I'm really happy to hear that! Enjoy a better day!
       
    8. jcm1918

      jcm1918 Member

      Tinnitus Since:
      9/12/2019
      Cause of Tinnitus:
      Left ear high frequency hearing loss
      Hello,

      I recently developed a case of tinnitus in my left ear. It came on suddenly on September 12. Although I have not had obvious exposure to loud noises, my hearing test showed some high frequency hearing loss in both ears, although I've so far had tinnitus only in my left ear. My left ear shows a deficiency to about 35 dB at 4000 Hz, but otherwise my hearing is ok. My right ear has a smaller deficiency to about 30 dB also at 4000 Hz, but no tinnitus. I had extreme stress (work, kids, lack of time) in the weeks leading up to the tinnitus, but no other obvious immediate cause (besides the hearing loss, which I did not know about).

      My question arises because I seem to have had some benefit from recently starting methylprednisolone. The first ENT I saw said steroids would likely not help someone with my profile. A second ENT I saw last week agreed that steroids were a long-shot, but agreed to prescribe a short-course given little downside. The prescribed course is Day 1 - 24 mg, Day 2 - 20 mg, Day 3 - 16 mg, Day 4 - 12 mg, Day 5 - 8 mg, and Day 6 - 4 mg. I am on Day 3 today.

      The steroids definitely seem to be helping the tinnitus, particularly in the morning and afternoon, but seem to wear off by the evening, and then the tinnitus returns.

      Does the fact that the methylprednisolone seems to help suggest anything? Should I ask for a higher dose of steroids? I've read some stories of steroids being taken early after onset of tinnitus making a difference, and I am desperate to take any possible precautions to increase the chances that the tinnitus does not become permanent.

      If it becomes permanent, I will deal with it, but in these early stages I am eager to take all possible steps I can now that might make a long-term difference. Any suggestions would be greatly appreciated!

      Thank you!
       
    9. Trixie2Love

      Trixie2Love Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      SSHL
      I saw an ENT 2+ months into having ear issues as my first doctor gave me Zyrtec and Flonase. He diagnosed me with SSHL & Tinnitus.

      It's a last ditch effort so late in the game but I am on Prednisone to try to save some of the hearing.

      However, I feel like the past few days my tinnitus is unbearably loud and is not fading into the background ever. Is this from the Prednisone?

      I'm considering stopping it as I can live with a hearing aid but the aggravated tinnitus is terrible.
       
    10. Daniel Lion
      Ape-like

      Daniel Lion Member Podcast Patron Benefactor Hall of Fame

      Location:
      SE Asia
      Tinnitus Since:
      2017
      Cause of Tinnitus:
      Noise trauma, hearing loss
      I’d stop, it should be used right away after a hearing trauma.
      2 months in is too late and any change would be placebo, unless your tinnitus is due to inflammation in your neck or jaw, which it sounds like it’s not.

      I’d stop, I don’t know anything about Zyrtec or Flonase, what are they?
      Sorry to hear about your troubles, take care.


      Edit: I just looked up the meds, they are for nasal congestion. Is that something you suffer from?
       
    11. Trixie2Love

      Trixie2Love Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      SSHL
      I am currently feeling the same - depressed due to tinnitus spike and scared to continue taking it. My fear is I now I have it in both ears and that it is indeed worse as I've been taking the Prednisone. I am 3 months in to SSHL so do not believe it is my ears adjusting to the loss of hearing at this point. I wish there was much more research done about this!
       
    12. unknownpleasures
      Tired

      unknownpleasures Member

      Location:
      London UK
      Tinnitus Since:
      2019
      Cause of Tinnitus:
      Unknown
      In all honesty and it's my opinion only. I think prednisone can make some of us jittery and in turn, the anxiety makes tinnitus worse. I am actually feeling calmer today. The lasting side effects I had were anxiety which seems to be lessening each day and have had odd periods where my heart seems to be beating a lot harder and this seems to be decreasing as well. Prednisone seems to be a hard drug for many and some have great benefits from it, for me, I will never take it again as made my anxiety and tinnitus so much worse. Today my tinnitus even feels better as I am calmer and slept better.

      I am also into three months with tinnitus and feel better at handling the spikes and I know it's still early days and there is still some way to go but remain positive. There are good and bad periods but I have learned already that stress and worry make things so much worse. The forum has provided me with so much hope as we are all in this together.
       
    13. Trixie2Love

      Trixie2Love Member

      Tinnitus Since:
      June 2019
      Cause of Tinnitus:
      SSHL
      I am in the EXACT same boat. I was given 5 days of 40mg prednisone. Asked for the full tapered dose and did 2 days 40, 2 days 60, 2 days 40 before stopping due to the horrific Tinnitus. I am now FAR worse off than when I started. I am hoping & praying that it subsides back to what it was before the steroids. Scared this will continue to be this horrific siren
       
      • Hug Hug x 1
    14. Mr.Drop

      Mr.Drop Member

      Tinnitus Since:
      07/2007
      Cause of Tinnitus:
      Ear trauma, ototoxicity
      I got back from the doctor today and since the antibiotics didn't help completely cure my sinus and I still get headaches around the ear and shooting pain in the ear a few times a day he decided to prescribe me Prednisone/Prednisolon. The order is 40mg for 3 days, after that 20mg for 4 more days. He told me I might have difficulty sleeping and hopes it will be worth it. I'm kind of worried about the sleep though as after sleeping my T is a bit easier to cope with. Did any of you who had Prednisone have difficulty sleeping because of it? The T does fluctuate daily however and maybe seen some improvement lately so my hopes are up it will help quiet it a bit more. I will keep you posted what my experience is with Prednisone.
       
    15. Mr.Drop

      Mr.Drop Member

      Tinnitus Since:
      07/2007
      Cause of Tinnitus:
      Ear trauma, ototoxicity
      May I ask did you notice the improvement immediately after the first dose?
       

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