TA 65 — Finding Out More

[Cal18]

I have meaning to post this because I feel it's something to be considered. Back in 2010 I suffered a pretty severe Paxil withdrawal which came with some nasty tinnitus (I thought it was loud then but I don't think I knew what loud was until now). All I know is that the withdrawal came with a lot of neurological issues all which seemed to speed in healing once I started taking TA 65. Now I can't say that the diminishing of the T was helped by taking it, but it did go down to a significantly reasonable volume (almost unnoticeable). It's marketed as an anti-aging/cellular repair supplement and comes with some pretty amazing stories.

The reason I haven't tried it for this T onset is because I suffered a severe reaction from an SSRI and can't take too many supplements. The company is TA Sciences and they are very legit.

They have never claimed it to help T but if it works on neuronal damage as well, I don't see why it wouldn't help - see page 57, second bullet of this presentation.

Now, I don't recommend anyone to jump in and start taking this out of desperation, it's also expensive $600 per bottle, and the last thing I would want is for anyone to get worse. I'm in contact with one of the doctors and have been asking some questions and I will report back.

Note: If you start searching for it, you will find scares that it can cause cancer but this has proven to be untrue. As you know, the media enjoys hanging on to that sort of hype.

 

[Cal18]

Main ingredient of TA 65 (Astragalus Mongholicus). Note that TA 65 is a more purified and potent version of this which is why it is expensive.

https://www.ncbi.nlm.nih.gov/pubmed/19578991

Anti-convulsant effect and mechanism of Astragalus mongholicus extract in vitro and in vivo: protection against oxidative damage and mitochondrial dysfunction.
Aldarmaa J1, Liu Z, Long J, Mo X, Ma J, Liu J.
Author information

Abstract
Astragalus mongholicus (AM) is a traditional medicinal herb used as a neuroprotective agent for its anxiolytic, antidepressant, antiamnestic, and antiaggresive effects. However, the mechanisms underlying its anti-convulsant properties are not well studied. In the present study, we examined the anticonvulsant effects on pentylenetetrazol (PTZ)-induced seizures in mice and the possible mechanisms of protection against oxidative damage and mitochondrial dysfunction in vitro. The behavioral studies showed that the root extract of AM had powerful anticonvulsant effects against seizures induced by PTZ and the biochemical studies showed that root extract of AM inhibited PTZ-induced increase in lipid peroxidation, protein oxidation and reactive oxygen species, and enhanced mitochondrial function. Electron spin resonance spectroscopy studies demonstrated that the extracts from the root and aerial parts of AM possess potent effects on scavenging hydroxyl and lipid free radicals. We found that AM extract significantly protected malondialdehyde-induced oxidative damage by ameliorating activities of the mitochondrial complexes I, II, malate dehydrogenase and mitochondrial membrane potential. These data suggest that the anti-convulsant effects of AM extract may be mediated by its protective actions against oxidative damage and amelioration of mitochondrial dysfunction.

 

[linearb]

worth mentioning that there are a lot of other brands of Cycloastragenol which are less expensive